Motif ID: Foxd2

Z-value: 0.804


Transcription factors associated with Foxd2:

Gene SymbolEntrez IDGene Name
Foxd2 ENSMUSG00000055210.3 Foxd2



Activity profile for motif Foxd2.

activity profile for motif Foxd2


Sorted Z-values histogram for motif Foxd2

Sorted Z-values for motif Foxd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd2

PNG image of the network

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Top targets:


Showing 1 to 20 of 110 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_101840602 5.256 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr16_+_43508118 4.767 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chr3_+_89520152 4.301 ENSMUST00000000811.7
 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr14_+_101840501 4.199 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr13_-_97747373 3.687 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr16_+_43235856 3.047 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr10_+_67096456 2.814 ENSMUST00000174317.1
 Jmjd1c
jumonji domain containing 1C
chr14_+_80000292 2.730 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr5_-_104114088 2.730 ENSMUST00000031249.3
 Sparcl1
SPARC-like 1
chr4_-_82850721 2.597 ENSMUST00000139401.1
 Zdhhc21
zinc finger, DHHC domain containing 21
chr14_-_30353468 2.419 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr1_-_157256682 2.307 ENSMUST00000134543.1
 Rasal2
RAS protein activator like 2
chr15_+_3270767 2.281 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chrX_-_105929333 2.088 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
 Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chrX_-_105929206 2.024 ENSMUST00000134381.1
ENSMUST00000154866.1
 Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr18_+_37504264 1.832 ENSMUST00000052179.6
 Pcdhb20
protocadherin beta 20
chr7_-_61982348 1.696 ENSMUST00000181804.1
ENSMUST00000181187.1
 A330076H08Rik

RIKEN cDNA A330076H08 gene

chr15_-_98607611 1.603 ENSMUST00000096224.4
 Adcy6
adenylate cyclase 6
chr1_-_165934900 1.600 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
 Pou2f1


POU domain, class 2, transcription factor 1


chr13_+_16014457 1.398 ENSMUST00000164993.1
 Inhba
inhibin beta-A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.3 5.2 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.0 4.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.4 2.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 2.7 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.3 2.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.8 2.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 2.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 2.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.5 1.6 GO:0035811 negative regulation of urine volume(GO:0035811)
0.2 1.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 1.4 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 1.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 1.0 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 1.0 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.9 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.7 GO:0005913 cell-cell adherens junction(GO:0005913)
1.3 5.2 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 4.3 GO:0031594 neuromuscular junction(GO:0031594)
0.2 2.7 GO:0042581 specific granule(GO:0042581)
0.2 2.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 2.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.6 GO:0031528 microvillus membrane(GO:0031528)
0.5 1.4 GO:0043512 inhibin A complex(GO:0043512)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 1.0 GO:0097342 ripoptosome(GO:0097342)
0.0 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 9.5 GO:0042805 actinin binding(GO:0042805)
0.1 7.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.7 5.2 GO:0015616 DNA translocase activity(GO:0015616)
1.1 4.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 3.3 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.8 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.1 2.7 GO:0045296 cadherin binding(GO:0045296)
0.1 2.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.4 2.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 2.3 GO:0008430 selenium binding(GO:0008430)
0.3 1.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.4 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)