Motif ID: Nfe2l2

Z-value: 0.533


Transcription factors associated with Nfe2l2:

Gene SymbolEntrez IDGene Name
Nfe2l2 ENSMUSG00000015839.6 Nfe2l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2l2mm10_v2_chr2_-_75704535_757046410.281.9e-01Click!


Activity profile for motif Nfe2l2.

activity profile for motif Nfe2l2


Sorted Z-values histogram for motif Nfe2l2

Sorted Z-values for motif Nfe2l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l2

PNG image of the network

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Top targets:


Showing 1 to 20 of 167 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_118961578 1.413 ENSMUST00000058651.4
 Lao1
L-amino acid oxidase 1
chr9_-_58313189 1.404 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr1_-_172219715 1.318 ENSMUST00000170700.1
ENSMUST00000003554.4
 Casq1

calsequestrin 1

chr3_-_116968827 1.279 ENSMUST00000119557.1
 Palmd
palmdelphin
chr3_-_116968969 0.992 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr1_+_165769392 0.938 ENSMUST00000040298.4
 Creg1
cellular repressor of E1A-stimulated genes 1
chr18_+_61639542 0.860 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr17_-_25570678 0.826 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr14_-_18239053 0.728 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr1_-_155146755 0.708 ENSMUST00000027744.8
 Mr1
major histocompatibility complex, class I-related
chr7_-_105482197 0.685 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr6_+_5725639 0.655 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr11_-_7213897 0.596 ENSMUST00000020702.4
ENSMUST00000135887.2
 Igfbp3

insulin-like growth factor binding protein 3

chr14_+_26514554 0.578 ENSMUST00000104927.1
 Gm2178
predicted gene 2178
chr9_-_116175318 0.564 ENSMUST00000061101.4
ENSMUST00000035014.6
 Tgfbr2

transforming growth factor, beta receptor II

chrX_-_51681856 0.548 ENSMUST00000114871.1
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr2_+_155775333 0.540 ENSMUST00000029141.5
 Mmp24
matrix metallopeptidase 24
chrX_-_51681703 0.520 ENSMUST00000088172.5
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr19_+_8929628 0.498 ENSMUST00000096241.4
 Eml3
echinoderm microtubule associated protein like 3
chr7_+_139834148 0.493 ENSMUST00000026548.7
 Gpr123
G protein-coupled receptor 123

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.4 1.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 1.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 0.8 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.7 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.0 0.7 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.2 0.6 GO:0072180 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.1 0.6 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.1 0.6 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.6 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.2 0.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.5 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 0.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.1 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 2.1 GO:0043197 dendritic spine(GO:0043197)
0.4 1.3 GO:0014802 terminal cisterna(GO:0014802)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 1.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.5 1.4 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 1.1 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 0.9 GO:0010181 FMN binding(GO:0010181)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)