Motif ID: Nfe2l2

Z-value: 0.533


Transcription factors associated with Nfe2l2:

Gene SymbolEntrez IDGene Name
Nfe2l2 ENSMUSG00000015839.6 Nfe2l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2l2mm10_v2_chr2_-_75704535_757046410.281.9e-01Click!


Activity profile for motif Nfe2l2.

activity profile for motif Nfe2l2


Sorted Z-values histogram for motif Nfe2l2

Sorted Z-values for motif Nfe2l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_118961578 1.413 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr9_-_58313189 1.404 ENSMUST00000061799.8
Loxl1
lysyl oxidase-like 1
chr1_-_172219715 1.318 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr3_-_116968827 1.279 ENSMUST00000119557.1
Palmd
palmdelphin
chr3_-_116968969 0.992 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr1_+_165769392 0.938 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chr18_+_61639542 0.860 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr17_-_25570678 0.826 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr14_-_18239053 0.728 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr1_-_155146755 0.708 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr7_-_105482197 0.685 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr6_+_5725639 0.655 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr11_-_7213897 0.596 ENSMUST00000020702.4
ENSMUST00000135887.2
Igfbp3

insulin-like growth factor binding protein 3

chr14_+_26514554 0.578 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr9_-_116175318 0.564 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chrX_-_51681856 0.548 ENSMUST00000114871.1
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr2_+_155775333 0.540 ENSMUST00000029141.5
Mmp24
matrix metallopeptidase 24
chrX_-_51681703 0.520 ENSMUST00000088172.5
Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr19_+_8929628 0.498 ENSMUST00000096241.4
Eml3
echinoderm microtubule associated protein like 3
chr7_+_139834148 0.493 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr17_-_47834682 0.489 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr2_-_44927161 0.479 ENSMUST00000130991.1
Gtdc1
glycosyltransferase-like domain containing 1
chr19_-_8929323 0.474 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr6_+_17463927 0.471 ENSMUST00000115442.1
Met
met proto-oncogene
chr18_+_61045139 0.470 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr18_-_53418004 0.461 ENSMUST00000025419.7
Ppic
peptidylprolyl isomerase C
chr17_+_86963279 0.447 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr14_+_30825580 0.440 ENSMUST00000006701.5
Tmem110
transmembrane protein 110
chr7_-_102250086 0.425 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr7_+_141468776 0.415 ENSMUST00000058746.5
Cd151
CD151 antigen
chr5_+_128601106 0.415 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr17_-_24644933 0.408 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr13_-_12461432 0.400 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
Lgals8



lectin, galactose binding, soluble 8



chr5_+_137758133 0.387 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chrX_-_52613936 0.365 ENSMUST00000114857.1
Gpc3
glypican 3
chr14_-_20393473 0.363 ENSMUST00000061444.3
Mrps16
mitochondrial ribosomal protein S16
chr4_-_126321669 0.357 ENSMUST00000102617.4
Adprhl2
ADP-ribosylhydrolase like 2
chr1_+_136018062 0.351 ENSMUST00000117950.1
Tmem9
transmembrane protein 9
chr5_-_69592274 0.346 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2


glucosamine-6-phosphate deaminase 2


chr1_+_136017967 0.345 ENSMUST00000063719.8
ENSMUST00000118832.1
Tmem9

transmembrane protein 9

chr11_-_109473598 0.326 ENSMUST00000070152.5
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_+_25395866 0.318 ENSMUST00000028328.2
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr9_+_107578887 0.315 ENSMUST00000149638.1
ENSMUST00000139274.1
ENSMUST00000130053.1
ENSMUST00000122985.1
ENSMUST00000127380.1
ENSMUST00000139581.1
Nat6





N-acetyltransferase 6





chr7_-_44849075 0.314 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr2_-_130397525 0.304 ENSMUST00000028897.7
Cpxm1
carboxypeptidase X 1 (M14 family)
chr19_-_4037910 0.300 ENSMUST00000169613.1
Gstp1
glutathione S-transferase, pi 1
chr2_+_164948219 0.294 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr17_-_25868727 0.290 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr2_+_25428699 0.290 ENSMUST00000102919.3
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr14_+_62292475 0.282 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr13_-_54611332 0.270 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr5_+_19907502 0.269 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_+_127800604 0.252 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr7_+_19181159 0.250 ENSMUST00000120595.1
ENSMUST00000048502.8
Eml2

echinoderm microtubule associated protein like 2

chr2_+_71453276 0.247 ENSMUST00000037210.8
Metap1d
methionyl aminopeptidase type 1D (mitochondrial)
chr5_+_31697960 0.247 ENSMUST00000114515.2
Bre
brain and reproductive organ-expressed protein
chr16_+_90220742 0.243 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr7_+_127800844 0.242 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr1_-_121332571 0.238 ENSMUST00000071064.6
Insig2
insulin induced gene 2
chrX_-_52613913 0.238 ENSMUST00000069360.7
Gpc3
glypican 3
chr5_+_31698050 0.236 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
Bre



brain and reproductive organ-expressed protein



chr2_-_44927206 0.234 ENSMUST00000100127.2
Gtdc1
glycosyltransferase-like domain containing 1
chr18_+_73863672 0.225 ENSMUST00000134847.1
Mro
maestro
chr2_+_112261926 0.212 ENSMUST00000028553.3
Nop10
NOP10 ribonucleoprotein
chr8_+_65967157 0.206 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chr7_-_104315455 0.201 ENSMUST00000106837.1
ENSMUST00000106839.2
ENSMUST00000070943.6
Trim12a


tripartite motif-containing 12A


chr7_+_45639964 0.200 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr9_-_42461414 0.196 ENSMUST00000066179.7
Tbcel
tubulin folding cofactor E-like
chr4_+_102421518 0.196 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr8_+_105326354 0.193 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr11_+_120673018 0.186 ENSMUST00000106158.2
ENSMUST00000103016.1
ENSMUST00000168714.1
Aspscr1


alveolar soft part sarcoma chromosome region, candidate 1 (human)


chr6_-_8259098 0.184 ENSMUST00000012627.4
Rpa3
replication protein A3
chr13_-_54611274 0.181 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr5_-_139484420 0.178 ENSMUST00000150992.1
Zfand2a
zinc finger, AN1-type domain 2A
chr2_+_120609383 0.173 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr3_-_146781351 0.173 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr14_-_37135310 0.165 ENSMUST00000165649.2
Ghitm
growth hormone inducible transmembrane protein
chr10_+_60277627 0.165 ENSMUST00000105465.1
ENSMUST00000177779.1
ENSMUST00000179238.1
ENSMUST00000004316.8
Psap



prosaposin



chr19_-_4042165 0.160 ENSMUST00000042700.9
Gstp2
glutathione S-transferase, pi 2
chr14_-_37135126 0.156 ENSMUST00000042564.9
Ghitm
growth hormone inducible transmembrane protein
chr5_-_45450121 0.153 ENSMUST00000127562.1
Qdpr
quinoid dihydropteridine reductase
chr1_-_33907721 0.153 ENSMUST00000115161.1
ENSMUST00000062289.8
Bend6

BEN domain containing 6

chr7_+_4460687 0.152 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr5_-_45450221 0.150 ENSMUST00000015950.5
Qdpr
quinoid dihydropteridine reductase
chr16_+_20548577 0.148 ENSMUST00000003319.5
Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chr16_+_58727910 0.148 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr1_-_120074023 0.144 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr5_-_45450143 0.144 ENSMUST00000154962.1
Qdpr
quinoid dihydropteridine reductase
chr4_+_123016590 0.141 ENSMUST00000102649.3
Trit1
tRNA isopentenyltransferase 1
chr11_-_59809774 0.141 ENSMUST00000047706.2
ENSMUST00000102697.3
Flcn

folliculin

chr1_-_168431695 0.141 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr3_-_89402650 0.140 ENSMUST00000168325.1
ENSMUST00000057431.5
Lenep

lens epithelial protein

chr11_+_60537978 0.139 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr2_-_26910569 0.139 ENSMUST00000015920.5
ENSMUST00000139815.1
ENSMUST00000102899.3
Med22


mediator complex subunit 22


chr8_-_105326252 0.139 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr2_-_163419508 0.136 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chr2_-_167043494 0.134 ENSMUST00000067584.6
Znfx1
zinc finger, NFX1-type containing 1
chr4_+_136357423 0.132 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr5_-_108675569 0.122 ENSMUST00000051757.7
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr7_+_44468020 0.121 ENSMUST00000117324.1
ENSMUST00000120852.1
ENSMUST00000118628.1
Josd2


Josephin domain containing 2


chr10_-_34418465 0.120 ENSMUST00000099973.3
ENSMUST00000105512.1
ENSMUST00000047885.7
Nt5dc1


5'-nucleotidase domain containing 1


chr7_+_44468051 0.120 ENSMUST00000118493.1
Josd2
Josephin domain containing 2
chr11_-_98438941 0.120 ENSMUST00000002655.7
Mien1
migration and invasion enhancer 1
chr11_-_50210765 0.115 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
Sqstm1


sequestosome 1


chr18_+_35598607 0.113 ENSMUST00000041314.8
ENSMUST00000115737.1
ENSMUST00000115736.1
ENSMUST00000115735.1
Paip2



polyadenylate-binding protein-interacting protein 2



chr5_+_19907774 0.112 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_-_167209149 0.111 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr16_+_18812286 0.109 ENSMUST00000005394.6
Ufd1l
ubiquitin fusion degradation 1 like
chr5_-_139484475 0.106 ENSMUST00000110851.1
ENSMUST00000079996.6
Zfand2a

zinc finger, AN1-type domain 2A

chr7_+_44848991 0.099 ENSMUST00000107885.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr2_+_25272475 0.097 ENSMUST00000028341.4
Anapc2
anaphase promoting complex subunit 2
chr8_+_106510853 0.096 ENSMUST00000080797.6
Cdh3
cadherin 3
chr17_+_34032348 0.095 ENSMUST00000173354.1
ENSMUST00000116612.2
Rxrb

retinoid X receptor beta

chr17_-_70998010 0.089 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr1_+_136131382 0.088 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr2_+_69647208 0.087 ENSMUST00000074963.2
ENSMUST00000112286.2
Bbs5

Bardet-Biedl syndrome 5 (human)

chr3_+_137623672 0.087 ENSMUST00000053855.7
Ddit4l
DNA-damage-inducible transcript 4-like
chr19_+_8839298 0.086 ENSMUST00000160556.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr9_-_9239052 0.085 ENSMUST00000093893.5
Arhgap42
Rho GTPase activating protein 42
chr3_+_108256926 0.084 ENSMUST00000090569.5
Psma5
proteasome (prosome, macropain) subunit, alpha type 5
chr6_-_30509738 0.080 ENSMUST00000115160.3
Tmem209
transmembrane protein 209
chr16_+_20694908 0.078 ENSMUST00000056518.6
Fam131a
family with sequence similarity 131, member A
chr18_+_37320374 0.077 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr12_-_85288419 0.072 ENSMUST00000121930.1
Acyp1
acylphosphatase 1, erythrocyte (common) type
chr18_-_34954302 0.071 ENSMUST00000025217.8
Hspa9
heat shock protein 9
chr14_-_20794009 0.070 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr7_-_44997221 0.068 ENSMUST00000152341.1
Bcl2l12
BCL2-like 12 (proline rich)
chr2_-_80581380 0.067 ENSMUST00000111760.2
Nckap1
NCK-associated protein 1
chr11_+_120673359 0.067 ENSMUST00000135346.1
ENSMUST00000127269.1
ENSMUST00000131727.2
ENSMUST00000149389.1
ENSMUST00000153346.1
Aspscr1




alveolar soft part sarcoma chromosome region, candidate 1 (human)




chr11_+_78178105 0.064 ENSMUST00000147819.1
Tlcd1
TLC domain containing 1
chr7_+_24271568 0.056 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr4_-_155863362 0.055 ENSMUST00000030949.3
Tas1r3
taste receptor, type 1, member 3
chr17_+_26933070 0.055 ENSMUST00000073724.5
Phf1
PHD finger protein 1
chr19_-_4839286 0.051 ENSMUST00000037246.5
Ccs
copper chaperone for superoxide dismutase
chr9_-_122310921 0.051 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr17_-_26939464 0.050 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr16_-_17531019 0.044 ENSMUST00000142666.1
ENSMUST00000100125.3
Thap7

THAP domain containing 7

chr19_+_29251748 0.041 ENSMUST00000065796.3
ENSMUST00000025705.6
Jak2

Janus kinase 2

chr1_-_136260873 0.038 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr2_-_120609283 0.038 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr19_-_6080311 0.037 ENSMUST00000159832.1
Vps51
vacuolar protein sorting 51 homolog (S. cerevisiae)
chr12_+_17544873 0.036 ENSMUST00000171737.1
Odc1
ornithine decarboxylase, structural 1
chr7_+_28881656 0.035 ENSMUST00000066880.4
Capn12
calpain 12
chr7_-_18616498 0.033 ENSMUST00000057810.6
Psg23
pregnancy-specific glycoprotein 23
chr9_-_27030010 0.033 ENSMUST00000034470.9
Vps26b
vacuolar protein sorting 26 homolog B (yeast)
chr5_+_30013141 0.033 ENSMUST00000026845.7
Il6
interleukin 6
chr9_+_65214690 0.033 ENSMUST00000069000.7
Parp16
poly (ADP-ribose) polymerase family, member 16
chr8_+_33653238 0.032 ENSMUST00000033992.8
Gsr
glutathione reductase
chr2_-_181691771 0.032 ENSMUST00000108778.1
ENSMUST00000165416.1
Rgs19

regulator of G-protein signaling 19

chr11_+_78178651 0.030 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr13_+_14613242 0.029 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr9_-_21239310 0.029 ENSMUST00000164812.1
ENSMUST00000049567.4
Keap1

kelch-like ECH-associated protein 1

chr19_+_23675839 0.028 ENSMUST00000056396.5
Gm6563
predicted pseudogene 6563
chr7_-_141429433 0.024 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr1_+_125676969 0.016 ENSMUST00000027581.6
Gpr39
G protein-coupled receptor 39
chr4_+_116685544 0.016 ENSMUST00000135573.1
ENSMUST00000151129.1
Prdx1

peroxiredoxin 1

chr8_+_69822429 0.015 ENSMUST00000164890.1
ENSMUST00000034325.4
Lpar2

lysophosphatidic acid receptor 2

chr4_+_5644084 0.014 ENSMUST00000054857.6
Fam110b
family with sequence similarity 110, member B
chr7_-_44997535 0.011 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr3_+_28805436 0.008 ENSMUST00000043867.5
Rpl22l1
ribosomal protein L22 like 1
chr19_-_4334001 0.008 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr5_+_138187485 0.005 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr3_+_122245625 0.005 ENSMUST00000178826.1
Gclm
glutamate-cysteine ligase, modifier subunit
chr11_+_97362396 0.002 ENSMUST00000045540.3
Socs7
suppressor of cytokine signaling 7
chr4_+_116685859 0.002 ENSMUST00000129315.1
ENSMUST00000106470.1
Prdx1

peroxiredoxin 1

chr7_+_102225812 0.000 ENSMUST00000142873.1
Pgap2
post-GPI attachment to proteins 2
chr2_+_91054054 0.000 ENSMUST00000002171.7
ENSMUST00000111441.3
Psmc3

proteasome (prosome, macropain) 26S subunit, ATPase 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 0.8 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.7 GO:0043465 regulation of fermentation(GO:0043465) negative regulation of fermentation(GO:1901003)
0.2 0.6 GO:0072180 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.2 1.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1 0.6 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.1 0.6 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.3 GO:0070488 neutrophil aggregation(GO:0070488)
0.1 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.3 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.4 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.4 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.5 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) phospholipid efflux(GO:0033700)
0.0 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.7 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.3 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.4 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 1.4 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.4 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.0 GO:0002295 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) T-helper 17 cell differentiation(GO:0072539)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.0 GO:0097296 response to interleukin-12(GO:0070671) activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.6 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.0 0.1 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0014802 terminal cisterna(GO:0014802)
0.2 0.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.0 0.1 GO:0036501 UFD1-NPL4 complex(GO:0036501)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 2.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 2.1 GO:0043197 dendritic spine(GO:0043197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.5 1.4 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.1 0.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.7 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0010181 FMN binding(GO:0010181)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 1.1 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)