Motif ID: Nr4a3
Z-value: 0.599
Transcription factors associated with Nr4a3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr4a3 | ENSMUSG00000028341.3 | Nr4a3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr4a3 | mm10_v2_chr4_+_48045144_48045160 | 0.35 | 9.9e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 4.2 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.1 | 0.7 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) |
0.1 | 0.4 | GO:0014873 | response to muscle activity involved in regulation of muscle adaptation(GO:0014873) |
0.1 | 0.4 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.1 | 0.5 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.1 | 0.4 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.1 | 0.6 | GO:1901524 | regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525) |
0.1 | 0.3 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.1 | 2.4 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.1 | 0.7 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.1 | 0.3 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.1 | 0.2 | GO:0070973 | COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.1 | 0.2 | GO:0070375 | ERK5 cascade(GO:0070375) |
0.1 | 0.2 | GO:0050787 | glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) glyoxal catabolic process(GO:1903190) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284) positive regulation of androgen receptor activity(GO:2000825) |
0.1 | 0.3 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
0.0 | 0.2 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.0 | 0.7 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
0.0 | 0.3 | GO:0030432 | peristalsis(GO:0030432) |
0.0 | 0.2 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
0.0 | 0.2 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.0 | 0.4 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.0 | 0.3 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
0.0 | 0.1 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.0 | 0.2 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.2 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
0.0 | 0.2 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
0.0 | 0.2 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 2.3 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.8 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.0 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
0.0 | 0.2 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.0 | 0.6 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 0.1 | GO:0010155 | regulation of proton transport(GO:0010155) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.7 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.1 | 1.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.0 | 0.3 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.2 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.0 | 0.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 0.7 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.3 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.2 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.2 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.2 | 0.7 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.1 | 0.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.1 | 0.3 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.1 | 0.4 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.1 | 0.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.1 | 0.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.1 | 0.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.1 | 0.2 | GO:0044388 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422) |
0.1 | 0.2 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.0 | 0.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.1 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
0.0 | 0.7 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.2 | GO:0015288 | porin activity(GO:0015288) |
0.0 | 0.3 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.0 | 0.3 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.0 | 0.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.8 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.1 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
0.0 | 0.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.2 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.0 | 0.1 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |