Motif ID: Nr4a3

Z-value: 0.599


Transcription factors associated with Nr4a3:

Gene SymbolEntrez IDGene Name
Nr4a3 ENSMUSG00000028341.3 Nr4a3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a3mm10_v2_chr4_+_48045144_480451600.359.9e-02Click!


Activity profile for motif Nr4a3.

activity profile for motif Nr4a3


Sorted Z-values histogram for motif Nr4a3

Sorted Z-values for motif Nr4a3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a3

PNG image of the network

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Top targets:


Showing 1 to 20 of 98 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1245685 3.058 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
 Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chrY_-_1245753 1.856 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr5_+_66968559 1.428 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr8_+_124793061 1.239 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr8_+_124793013 1.144 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr15_+_25773985 0.777 ENSMUST00000125667.1
 Myo10
myosin X
chr7_+_102267795 0.750 ENSMUST00000033289.4
 Stim1
stromal interaction molecule 1
chr7_-_98162318 0.731 ENSMUST00000107112.1
 Capn5
calpain 5
chr11_-_55033398 0.726 ENSMUST00000108883.3
ENSMUST00000102727.2
 Anxa6

annexin A6

chr5_+_66968416 0.700 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr15_-_79804717 0.697 ENSMUST00000023057.8
 Nptxr
neuronal pentraxin receptor
chr19_-_4334001 0.685 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A
chr6_-_138426735 0.639 ENSMUST00000162932.1
 Lmo3
LIM domain only 3
chr4_+_99955715 0.522 ENSMUST00000102783.4
 Pgm2
phosphoglucomutase 2
chr6_-_113531575 0.505 ENSMUST00000032425.5
 Emc3
ER membrane protein complex subunit 3
chr15_-_76918010 0.482 ENSMUST00000048854.7
 Zfp647
zinc finger protein 647
chr2_-_165283599 0.449 ENSMUST00000155289.1
 Slc35c2
solute carrier family 35, member C2
chr7_+_45896941 0.448 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143

chr16_-_4523056 0.442 ENSMUST00000090500.3
ENSMUST00000023161.7
 Srl

sarcalumenin

chr16_+_10545390 0.434 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
 Clec16a


C-type lectin domain family 16, member A



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 2.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 2.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.7 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.1 0.7 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.7 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 0.6 GO:1901524 regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.4 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.3 GO:0030432 peristalsis(GO:0030432)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.2 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.2 0.7 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.2 GO:0044388 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) small protein activating enzyme binding(GO:0044388) cupric ion binding(GO:1903135) cuprous ion binding(GO:1903136) glyoxalase (glycolic acid-forming) activity(GO:1990422)
0.1 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0015288 porin activity(GO:0015288)