Motif ID: Atf5

Z-value: 0.701


Transcription factors associated with Atf5:

Gene SymbolEntrez IDGene Name
Atf5 ENSMUSG00000038539.8 Atf5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf5mm10_v2_chr7_-_44816586_44816658-0.472.2e-02Click!


Activity profile for motif Atf5.

activity profile for motif Atf5


Sorted Z-values histogram for motif Atf5

Sorted Z-values for motif Atf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf5

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_102529025 2.012 ENSMUST00000096143.1
Atf7
activating transcription factor 7
chr16_+_43503607 1.951 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr13_+_104287855 1.924 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr4_-_82705735 1.893 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr1_-_56971762 1.751 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chrX_+_41401128 1.700 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr14_-_101609033 1.419 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chrX_+_41401304 1.408 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr5_+_149678224 1.155 ENSMUST00000100404.3
B3galtl
beta 1,3-galactosyltransferase-like
chr7_+_51621830 1.140 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chrX_+_41401476 1.083 ENSMUST00000165288.1
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr3_+_114030532 1.051 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chr17_-_46031813 1.034 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr1_-_45503282 0.995 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr4_-_11322109 0.957 ENSMUST00000084892.5
ENSMUST00000128024.1
Dpy19l4

dpy-19-like 4 (C. elegans)

chr16_+_38089001 0.952 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr4_-_91376433 0.902 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chrX_-_41911877 0.871 ENSMUST00000047037.8
Thoc2
THO complex 2
chr4_+_86748526 0.865 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c

DENN/MADD domain containing 4C

chr3_-_18243289 0.855 ENSMUST00000035625.6
Cyp7b1
cytochrome P450, family 7, subfamily b, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 2.1 GO:0060976 coronary vasculature development(GO:0060976)
0.5 1.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.2 GO:0030035 microspike assembly(GO:0030035)
0.2 1.1 GO:0035989 tendon development(GO:0035989)
0.1 1.1 GO:0001504 neurotransmitter uptake(GO:0001504)
0.3 1.0 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 1.0 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 1.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.1 0.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 0.6 GO:0032632 interleukin-3 production(GO:0032632)
0.2 0.6 GO:1990743 protein sialylation(GO:1990743)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.6 GO:0030175 filopodium(GO:0030175)
0.0 1.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.0 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.0 GO:0005604 basement membrane(GO:0005604)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.5 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0032584 growth cone membrane(GO:0032584)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 2.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.3 1.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 1.0 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.1 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)