Motif ID: Atf5
Z-value: 0.701
Transcription factors associated with Atf5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Atf5 | ENSMUSG00000038539.8 | Atf5 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Atf5 | mm10_v2_chr7_-_44816586_44816658 | -0.47 | 2.2e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.9 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
0.3 | 1.0 | GO:1902336 | neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) |
0.3 | 1.0 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.3 | 1.0 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
0.3 | 1.0 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
0.2 | 1.1 | GO:0035989 | tendon development(GO:0035989) |
0.2 | 0.6 | GO:0032632 | interleukin-3 production(GO:0032632) |
0.2 | 0.6 | GO:1990743 | protein sialylation(GO:1990743) |
0.2 | 1.4 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
0.1 | 1.2 | GO:0030035 | microspike assembly(GO:0030035) |
0.1 | 0.8 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.1 | 0.5 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
0.1 | 1.7 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.1 | 0.3 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
0.1 | 0.4 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.1 | 4.2 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.1 | 0.5 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
0.1 | 0.3 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.1 | 0.8 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
0.1 | 0.6 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
0.1 | 0.8 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.1 | 0.4 | GO:0042701 | progesterone secretion(GO:0042701) |
0.1 | 0.2 | GO:0044333 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.1 | 0.6 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.1 | 1.1 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
0.1 | 0.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.4 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
0.1 | 1.9 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.5 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
0.0 | 0.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.0 | 0.2 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.0 | 0.1 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.0 | 0.8 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.0 | 0.0 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
0.0 | 2.1 | GO:0060976 | coronary vasculature development(GO:0060976) |
0.0 | 0.1 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
0.0 | 0.5 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.0 | 0.3 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
0.0 | 0.4 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.0 | 0.4 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.0 | 0.1 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.0 | 0.4 | GO:0042474 | middle ear morphogenesis(GO:0042474) |
0.0 | 0.1 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.0 | 0.1 | GO:0060536 | cartilage morphogenesis(GO:0060536) |
0.0 | 0.4 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.0 | 0.6 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 4.2 | GO:0043083 | synaptic cleft(GO:0043083) |
0.3 | 1.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.1 | 0.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
0.1 | 0.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.1 | 0.6 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 0.4 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.1 | 0.9 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.1 | 1.9 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.1 | 1.0 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.1 | 0.8 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 0.5 | GO:0044308 | axonal spine(GO:0044308) |
0.1 | 0.6 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 0.9 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.5 | GO:0032584 | growth cone membrane(GO:0032584) |
0.0 | 0.3 | GO:1904949 | ATPase complex(GO:1904949) |
0.0 | 1.1 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.0 | 1.0 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 1.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.9 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 1.6 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 1.9 | GO:0034399 | nuclear periphery(GO:0034399) |
0.0 | 0.1 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.0 | 1.0 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.3 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.1 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 4.2 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.3 | 1.0 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.1 | 0.6 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.1 | 0.6 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.1 | 0.4 | GO:0071532 | ornithine decarboxylase inhibitor activity(GO:0008073) ankyrin repeat binding(GO:0071532) |
0.1 | 0.9 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 1.4 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.1 | 0.3 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
0.1 | 1.1 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.1 | 0.6 | GO:0015299 | solute:proton antiporter activity(GO:0015299) |
0.1 | 1.9 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 0.3 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
0.1 | 1.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.3 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.0 | 2.0 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 0.5 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.2 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.1 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.0 | 0.5 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.0 | 0.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 1.0 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
0.0 | 0.5 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.4 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 1.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |