Motif ID: Ppara

Z-value: 1.560


Transcription factors associated with Ppara:

Gene SymbolEntrez IDGene Name
Ppara ENSMUSG00000022383.7 Ppara



Activity profile for motif Ppara.

activity profile for motif Ppara


Sorted Z-values histogram for motif Ppara

Sorted Z-values for motif Ppara



Network of associatons between targets according to the STRING database.



First level regulatory network of Ppara

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_61523889 9.738 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr13_-_9878998 7.135 ENSMUST00000063093.9
 Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr2_-_13011747 5.808 ENSMUST00000061545.5
 C1ql3
C1q-like 3
chr1_+_6487231 5.265 ENSMUST00000140079.1
ENSMUST00000131494.1
 St18

suppression of tumorigenicity 18

chr1_+_6734827 5.081 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr7_-_74554474 4.841 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
 Slco3a1


solute carrier organic anion transporter family, member 3a1


chr1_-_84696182 4.740 ENSMUST00000049126.6
 Dner
delta/notch-like EGF-related receptor
chrX_-_72656135 4.688 ENSMUST00000055966.6
 Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr18_+_77185815 4.486 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr2_+_121295437 4.414 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr8_+_118283719 4.124 ENSMUST00000117160.1
 Cdh13
cadherin 13
chr7_-_25005895 4.015 ENSMUST00000102858.3
ENSMUST00000080882.6
 Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr4_+_13751297 4.000 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_94875600 3.938 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr17_+_28142267 3.873 ENSMUST00000043503.3
 Scube3
signal peptide, CUB domain, EGF-like 3
chr17_+_43952999 3.868 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr9_-_119578981 3.812 ENSMUST00000117911.1
ENSMUST00000120420.1
 Scn5a

sodium channel, voltage-gated, type V, alpha

chr15_-_45114926 3.757 ENSMUST00000022967.5
 Kcnv1
potassium channel, subfamily V, member 1
chr1_+_90203980 3.446 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr12_+_109545390 3.221 ENSMUST00000146701.1
 Meg3
maternally expressed 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 305 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 9.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.6 8.3 GO:0015732 prostaglandin transport(GO:0015732)
0.2 8.0 GO:0014003 oligodendrocyte development(GO:0014003)
0.5 5.7 GO:0060539 diaphragm development(GO:0060539)
0.2 5.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 5.5 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1 5.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.2 5.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.4 4.7 GO:0007220 Notch receptor processing(GO:0007220)
0.3 4.3 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 4.3 GO:0050807 regulation of synapse organization(GO:0050807)
1.0 4.1 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 3.9 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.3 3.8 GO:0086017 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) Purkinje myocyte action potential(GO:0086017) membrane depolarization during SA node cell action potential(GO:0086046)
0.5 3.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.4 3.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.2 3.6 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 3.5 GO:0051017 actin filament bundle assembly(GO:0051017)
0.2 3.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.6 3.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 11.0 GO:0009986 cell surface(GO:0009986)
0.1 9.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 9.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 9.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.4 8.7 GO:0032279 asymmetric synapse(GO:0032279)
0.4 7.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 7.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 4.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.2 GO:0005884 actin filament(GO:0005884)
0.1 4.1 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.7 3.7 GO:0032426 stereocilium tip(GO:0032426)
0.0 3.7 GO:0005604 basement membrane(GO:0005604)
0.6 3.6 GO:0097427 microtubule bundle(GO:0097427)
0.5 3.5 GO:0044326 dendritic spine neck(GO:0044326)
0.1 3.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 3.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.4 2.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 214 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 9.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 8.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
1.1 7.9 GO:0015198 oligopeptide transporter activity(GO:0015198)
1.3 7.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 6.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.4 6.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.8 5.7 GO:0015197 peptide transporter activity(GO:0015197)
0.9 5.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.2 4.9 GO:0005112 Notch binding(GO:0005112)
0.1 4.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.3 4.5 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 4.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 4.3 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 4.2 GO:0002039 p53 binding(GO:0002039)
0.8 4.1 GO:0055100 adiponectin binding(GO:0055100)
0.8 4.0 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.6 3.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 3.9 GO:0005096 GTPase activator activity(GO:0005096)
0.5 3.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 3.7 GO:0008266 poly(U) RNA binding(GO:0008266)