Motif ID: Bcl6b

Z-value: 0.656


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.272.2e-01Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_64046925 2.250 ENSMUST00000107377.3
Tnc
tenascin C
chr1_-_173942445 2.155 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr10_+_57794335 1.756 ENSMUST00000151623.1
ENSMUST00000020022.7
Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr16_-_74411776 1.459 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr9_-_90255927 1.455 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr19_-_5797410 1.274 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_74411292 1.215 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chrX_+_151344171 1.162 ENSMUST00000073364.5
Fam120c
family with sequence similarity 120, member C
chr13_-_98815408 0.995 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr10_-_95417099 0.911 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr12_-_98577940 0.829 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr2_+_119594288 0.800 ENSMUST00000147425.1
ENSMUST00000153581.1
1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr6_+_149309391 0.800 ENSMUST00000130664.1
ENSMUST00000046689.6
2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr6_+_149309444 0.770 ENSMUST00000100765.4
2810474O19Rik
RIKEN cDNA 2810474O19 gene
chr10_-_95416850 0.767 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr16_-_34263179 0.762 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr16_-_34262830 0.726 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr18_-_41951187 0.704 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr15_+_25752860 0.702 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr8_+_13907748 0.688 ENSMUST00000043520.3
Fbxo25
F-box protein 25
chr10_+_81633694 0.591 ENSMUST00000140345.1
ENSMUST00000126323.1
Ankrd24

ankyrin repeat domain 24

chr16_-_34262945 0.590 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr17_-_45592485 0.584 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr8_-_105568298 0.584 ENSMUST00000005849.5
Agrp
agouti related protein
chr5_-_150665560 0.579 ENSMUST00000118316.1
N4bp2l2
NEDD4 binding protein 2-like 2
chr11_+_70764209 0.578 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr17_-_45592569 0.557 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr18_+_37320374 0.550 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr12_-_40134175 0.548 ENSMUST00000078481.7
ENSMUST00000002640.5
Scin

scinderin

chr2_-_180824596 0.537 ENSMUST00000148700.1
Gm14340
predicted gene 14340
chr1_+_82316452 0.494 ENSMUST00000027322.7
Rhbdd1
rhomboid domain containing 1
chr2_-_65567505 0.440 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_+_130079370 0.415 ENSMUST00000040721.8
Tpst1
protein-tyrosine sulfotransferase 1
chr10_-_86705485 0.415 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr2_-_65567465 0.402 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_+_95588990 0.397 ENSMUST00000177399.1
Golph3l
golgi phosphoprotein 3-like
chr2_+_175283298 0.384 ENSMUST00000098998.3
Gm14440
predicted gene 14440
chr6_-_128355826 0.372 ENSMUST00000001562.6
Tulp3
tubby-like protein 3
chr7_+_43579577 0.362 ENSMUST00000058104.7
Zfp719
zinc finger protein 719
chr3_+_95588960 0.353 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
Golph3l


golgi phosphoprotein 3-like


chr6_+_34598500 0.338 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr18_+_42275353 0.320 ENSMUST00000046972.7
ENSMUST00000091920.5
Rbm27

RNA binding motif protein 27

chr6_+_29361410 0.301 ENSMUST00000156163.1
Calu
calumenin
chr3_+_95588928 0.300 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr5_-_123140135 0.298 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr8_+_27042555 0.289 ENSMUST00000033875.8
ENSMUST00000098851.4
Prosc

proline synthetase co-transcribed

chr11_+_58432559 0.284 ENSMUST00000108825.1
Gm12253
predicted gene 12253
chr2_-_28583189 0.279 ENSMUST00000113889.2
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr1_-_136230289 0.269 ENSMUST00000150163.1
ENSMUST00000144464.1
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr6_+_34598530 0.259 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr8_+_25601591 0.243 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr8_+_12915879 0.242 ENSMUST00000110876.2
ENSMUST00000110879.2
Mcf2l

mcf.2 transforming sequence-like

chr5_-_150665315 0.236 ENSMUST00000141857.1
N4bp2l2
NEDD4 binding protein 2-like 2
chr18_+_33794882 0.228 ENSMUST00000146010.2
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr9_+_122923050 0.225 ENSMUST00000051667.7
ENSMUST00000148851.1
Zfp105

zinc finger protein 105

chr18_+_33794915 0.225 ENSMUST00000179138.1
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr6_+_124916863 0.183 ENSMUST00000069553.2
A230083G16Rik
RIKEN cDNA A230083G16 gene
chr7_+_48789003 0.167 ENSMUST00000118927.1
ENSMUST00000125280.1
Zdhhc13

zinc finger, DHHC domain containing 13

chr7_-_16221993 0.159 ENSMUST00000118795.1
ENSMUST00000119102.1
ENSMUST00000094816.2
ENSMUST00000163968.1
ENSMUST00000121123.1
Dhx34




DEAH (Asp-Glu-Ala-His) box polypeptide 34




chr2_-_77946331 0.136 ENSMUST00000111821.2
ENSMUST00000111818.1
Cwc22

CWC22 spliceosome-associated protein homolog (S. cerevisiae)

chr3_+_84925476 0.123 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chrX_+_152233228 0.117 ENSMUST00000112588.2
ENSMUST00000082177.6
Kdm5c

lysine (K)-specific demethylase 5C

chrX_+_74429671 0.110 ENSMUST00000114127.1
ENSMUST00000064407.3
ENSMUST00000156707.1
Ikbkg


inhibitor of kappaB kinase gamma


chr11_+_95712673 0.100 ENSMUST00000107717.1
Zfp652
zinc finger protein 652
chr2_-_77946375 0.091 ENSMUST00000065889.3
Cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr4_+_149485260 0.087 ENSMUST00000030842.7
Lzic
leucine zipper and CTNNBIP1 domain containing
chr11_-_80142123 0.084 ENSMUST00000131601.1
Tefm
transcription elongation factor, mitochondrial
chr3_+_84593547 0.081 ENSMUST00000062623.3
Tigd4
tigger transposable element derived 4
chr6_+_106769120 0.073 ENSMUST00000113247.1
ENSMUST00000113249.1
ENSMUST00000057578.9
ENSMUST00000113248.1
Trnt1



tRNA nucleotidyl transferase, CCA-adding, 1



chr4_+_155562348 0.049 ENSMUST00000030939.7
Nadk
NAD kinase
chr19_-_10555724 0.049 ENSMUST00000145210.1
ENSMUST00000123788.1
ENSMUST00000059582.2
ENSMUST00000154383.1
Tmem216



transmembrane protein 216



chr18_-_3281036 0.040 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr9_+_121938099 0.022 ENSMUST00000063103.4
1700048O20Rik
RIKEN cDNA 1700048O20 gene
chr15_-_54919961 0.009 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr4_+_3574872 0.008 ENSMUST00000052712.5
Tgs1
trimethylguanosine synthase homolog (S. cerevisiae)
chr2_-_73486456 0.008 ENSMUST00000141264.1
Wipf1
WAS/WASL interacting protein family, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 2.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 1.3 GO:0035063 nuclear speck organization(GO:0035063)
0.3 0.8 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.3 2.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 1.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 0.8 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.5 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 1.1 GO:0015862 uridine transport(GO:0015862)
0.1 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.6 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.4 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 1.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 2.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 1.0 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 1.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:0006940 regulation of smooth muscle contraction(GO:0006940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 2.7 GO:0030673 axolemma(GO:0030673)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.5 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0045545 syndecan binding(GO:0045545)
0.3 1.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 2.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.4 GO:0046790 virion binding(GO:0046790)
0.0 0.8 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 1.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)