Motif ID: E2f7

Z-value: 1.225


Transcription factors associated with E2f7:

Gene SymbolEntrez IDGene Name
E2f7 ENSMUSG00000020185.10 E2f7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f7mm10_v2_chr10_+_110745433_1107455720.048.5e-01Click!


Activity profile for motif E2f7.

activity profile for motif E2f7


Sorted Z-values histogram for motif E2f7

Sorted Z-values for motif E2f7



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f7

PNG image of the network

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Top targets:


Showing 1 to 20 of 122 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3013140 6.913 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3037111 6.388 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3025417 5.558 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3017408 5.073 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 4.813 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr19_-_41206774 3.779 ENSMUST00000025986.7
ENSMUST00000169941.1
 Tll2

tolloid-like 2

chr12_+_112146187 2.017 ENSMUST00000128402.2
 Kif26a
kinesin family member 26A
chr10_-_69352886 1.356 ENSMUST00000119827.1
ENSMUST00000020099.5
 Cdk1

cyclin-dependent kinase 1

chr15_+_102296256 1.198 ENSMUST00000064924.4
 Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr12_+_24708241 1.150 ENSMUST00000020980.5
 Rrm2
ribonucleotide reductase M2
chr12_+_24708984 1.061 ENSMUST00000154588.1
 Rrm2
ribonucleotide reductase M2
chr11_+_102248842 0.959 ENSMUST00000100392.4
 BC030867
cDNA sequence BC030867
chr13_-_21716143 0.878 ENSMUST00000091756.1
 Hist1h2bl
histone cluster 1, H2bl
chr8_+_75109528 0.824 ENSMUST00000164309.1
 Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr13_+_21833736 0.804 ENSMUST00000180288.1
ENSMUST00000110467.1
 Hist1h2br

histone cluster 1 H2br

chr13_+_22043189 0.796 ENSMUST00000110452.1
 Hist1h2bj
histone cluster 1, H2bj
chr13_+_22035821 0.791 ENSMUST00000110455.2
 Hist1h2bk
histone cluster 1, H2bk
chr14_+_5071040 0.751 ENSMUST00000163719.1
 Gm8281
predicted gene, 8281
chr3_+_108383829 0.735 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
 Psrc1


proline/serine-rich coiled-coil 1


chr5_+_130448801 0.681 ENSMUST00000111288.2
 Caln1
calneuron 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 3.8 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 2.9 GO:0006342 chromatin silencing(GO:0006342)
0.2 2.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 2.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 2.0 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.9 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.3 GO:0090166 Golgi disassembly(GO:0090166)
0.1 1.2 GO:1901970 positive regulation of mitotic sister chromatid separation(GO:1901970)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 0.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.2 0.6 GO:1904008 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.1 0.6 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.5 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.5 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.5 GO:1902570 protein localization to nucleolus(GO:1902570)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.6 GO:0072686 mitotic spindle(GO:0072686)
0.4 2.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0005915 zonula adherens(GO:0005915)
0.2 0.5 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 2.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.0 GO:0050733 RS domain binding(GO:0050733)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432) phospholipase binding(GO:0043274)
0.1 0.5 GO:0070883 importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)