Motif ID: Six3_Six1_Six2
Z-value: 0.825
Transcription factors associated with Six3_Six1_Six2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Six1 | ENSMUSG00000051367.8 | Six1 |
| Six2 | ENSMUSG00000024134.10 | Six2 |
| Six3 | ENSMUSG00000038805.9 | Six3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Six1 | mm10_v2_chr12_-_73047179_73047179 | 0.60 | 2.7e-03 | Click! |
| Six3 | mm10_v2_chr17_+_85613432_85613608 | -0.32 | 1.3e-01 | Click! |
| Six2 | mm10_v2_chr17_-_85688252_85688275 | 0.31 | 1.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 64 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 24 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 6.2 | GO:0051923 | sulfation(GO:0051923) |
| 0.8 | 2.5 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.2 | 1.9 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.3 | 1.8 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.0 | 1.6 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.1 | 1.5 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 1.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 1.3 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 1.0 | GO:0001706 | endoderm formation(GO:0001706) |
| 0.3 | 0.8 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
| 0.1 | 0.6 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.1 | 0.5 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.1 | 0.5 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.1 | 0.4 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.0 | 0.4 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.1 | 0.3 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.0 | 0.3 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.1 | 0.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.1 | 0.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.2 | GO:0015670 | carbon dioxide transport(GO:0015670) |
Gene overrepresentation in cellular_component category:
Showing 1 to 12 of 12 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.5 | GO:0044327 | dendritic spine membrane(GO:0032591) dendritic spine head(GO:0044327) |
| 0.0 | 2.0 | GO:0031513 | nonmotile primary cilium(GO:0031513) |
| 0.2 | 1.8 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.4 | 1.4 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.0 | 1.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.8 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 0.4 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.1 | 0.4 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.0 | 0.4 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.2 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.1 | GO:0070939 | Dsl1p complex(GO:0070939) |
Gene overrepresentation in molecular_function category:
Showing 1 to 18 of 18 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.2 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.4 | 2.5 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.0 | 1.9 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 1.8 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 1.4 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.0 | 1.1 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
| 0.0 | 1.1 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
| 0.0 | 0.8 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.2 | 0.6 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
| 0.0 | 0.5 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 0.4 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.0 | 0.4 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 0.3 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.1 | 0.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.0 | 0.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.1 | GO:0008410 | CoA-transferase activity(GO:0008410) |
| 0.0 | 0.1 | GO:0034452 | dynactin binding(GO:0034452) |
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