Motif ID: Elf1_Elf2_Etv2_Elf4

Z-value: 1.634

Transcription factors associated with Elf1_Elf2_Etv2_Elf4:

Gene SymbolEntrez IDGene Name
Elf1 ENSMUSG00000036461.9 Elf1
Elf2 ENSMUSG00000037174.12 Elf2
Elf4 ENSMUSG00000031103.6 Elf4
Etv2 ENSMUSG00000006311.8 Etv2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf2mm10_v2_chr3_-_51340555_51340584-0.482.0e-02Click!
Elf1mm10_v2_chr14_+_79481164_79481194-0.311.5e-01Click!
Elf4mm10_v2_chrX_-_48454152_48454193-0.048.7e-01Click!


Activity profile for motif Elf1_Elf2_Etv2_Elf4.

activity profile for motif Elf1_Elf2_Etv2_Elf4


Sorted Z-values histogram for motif Elf1_Elf2_Etv2_Elf4

Sorted Z-values for motif Elf1_Elf2_Etv2_Elf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf1_Elf2_Etv2_Elf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 3.996 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr16_-_22161450 3.576 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr4_-_63403330 2.341 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr1_-_180330550 2.294 ENSMUST00000050581.3
 Gm5069
predicted pseudogene 5069
chr18_+_62548911 2.261 ENSMUST00000055725.4
ENSMUST00000162365.1
 Spink10

serine peptidase inhibitor, Kazal type 10

chr3_-_89418287 2.219 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr13_+_90089705 2.044 ENSMUST00000012566.8
 Tmem167
transmembrane protein 167
chr11_-_20112876 1.981 ENSMUST00000000137.7
 Actr2
ARP2 actin-related protein 2
chr10_-_6980376 1.978 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr11_-_94653964 1.934 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr9_+_66126611 1.899 ENSMUST00000034945.5
 Fam96a
family with sequence similarity 96, member A
chr4_+_124850679 1.876 ENSMUST00000102628.4
 Yrdc
yrdC domain containing (E.coli)
chr1_+_84839833 1.862 ENSMUST00000097672.3
 Fbxo36
F-box protein 36
chr10_+_26229707 1.796 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr9_-_66514567 1.773 ENSMUST00000056890.8
 Fbxl22
F-box and leucine-rich repeat protein 22
chr7_-_118855984 1.764 ENSMUST00000116280.2
ENSMUST00000106550.3
ENSMUST00000063607.5
 Knop1


lysine rich nucleolar protein 1


chr2_+_74825802 1.703 ENSMUST00000028511.7
 Mtx2
metaxin 2
chr1_-_133610215 1.648 ENSMUST00000164574.1
ENSMUST00000166291.1
ENSMUST00000164096.1
 Snrpe


small nuclear ribonucleoprotein E


chr16_+_48994185 1.648 ENSMUST00000117994.1
ENSMUST00000048374.5
 C330027C09Rik

RIKEN cDNA C330027C09 gene

chr17_+_80290206 1.639 ENSMUST00000061703.9
 Morn2
MORN repeat containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 920 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.6 GO:0006412 translation(GO:0006412)
0.2 9.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 9.0 GO:0006413 translational initiation(GO:0006413)
0.4 8.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 7.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 6.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 5.1 GO:0051028 mRNA transport(GO:0051028)
0.1 4.6 GO:1903214 regulation of protein targeting to mitochondrion(GO:1903214)
0.1 4.5 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.7 4.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 4.3 GO:0045116 protein neddylation(GO:0045116)
0.2 4.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 4.3 GO:0006284 base-excision repair(GO:0006284)
0.1 4.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 4.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 3.8 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.2 3.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 3.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 3.7 GO:0032543 mitochondrial translation(GO:0032543)
0.2 3.6 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 351 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 23.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 17.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 13.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 8.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 8.3 GO:0070469 respiratory chain(GO:0070469)
0.2 8.2 GO:0015934 large ribosomal subunit(GO:0015934)
0.5 5.9 GO:0005687 U4 snRNP(GO:0005687)
0.1 5.4 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 5.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 4.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 4.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 4.3 GO:0005681 spliceosomal complex(GO:0005681)
0.1 4.2 GO:0072686 mitotic spindle(GO:0072686)
0.3 4.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 3.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 3.9 GO:0005839 proteasome core complex(GO:0005839)
0.5 3.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.4 3.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 3.5 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.4 3.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 509 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 47.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 14.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 8.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 6.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.7 6.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.4 6.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 6.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 6.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 4.8 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 3.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 3.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.4 3.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 3.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.4 3.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 3.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.3 GO:0019003 GDP binding(GO:0019003)
0.2 3.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 3.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.4 3.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)