Motif ID: Foxc2
Z-value: 0.704
Transcription factors associated with Foxc2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxc2 | ENSMUSG00000046714.6 | Foxc2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxc2 | mm10_v2_chr8_+_121116163_121116177 | 0.07 | 7.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 128 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 56 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.9 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 1.0 | 3.9 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
| 0.3 | 3.4 | GO:0007379 | segment specification(GO:0007379) |
| 1.1 | 3.3 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.1 | 3.3 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 3.2 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.2 | 2.0 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.3 | 1.7 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.2 | 1.6 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.0 | 1.6 | GO:0021766 | hippocampus development(GO:0021766) |
| 0.2 | 1.4 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366) |
| 0.1 | 1.3 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.1 | 1.1 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.1 | 1.1 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) |
| 0.2 | 1.0 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.0 | 1.0 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.3 | 0.9 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 0.3 | 0.9 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.3 | 0.9 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
| 0.2 | 0.8 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
Gene overrepresentation in cellular_component category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 3.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 1.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.6 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 1.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.9 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.8 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.8 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.4 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.4 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.0 | 0.4 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.3 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 30 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.3 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.1 | 2.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.5 | 1.6 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.0 | 1.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.3 | 1.2 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.3 | 1.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.1 | 1.1 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 1.1 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.3 | 1.0 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.2 | 1.0 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.0 | 1.0 | GO:0002039 | p53 binding(GO:0002039) |
| 0.2 | 0.9 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
| 0.1 | 0.9 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 0.7 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.6 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.5 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 0.4 | GO:0008502 | melatonin receptor activity(GO:0008502) |
