Motif ID: Hif1a
Z-value: 0.615

Transcription factors associated with Hif1a:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hif1a | ENSMUSG00000021109.7 | Hif1a |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hif1a | mm10_v2_chr12_+_73907904_73907970 | -0.61 | 2.1e-03 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 71 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 5.0 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.3 | 1.4 | GO:0019659 | lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
0.4 | 1.3 | GO:0043379 | memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.2 | 1.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.0 | 1.3 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
0.1 | 1.0 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 1.0 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
0.2 | 0.7 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.1 | 0.7 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.0 | 0.7 | GO:0045214 | sarcomere organization(GO:0045214) |
0.0 | 0.7 | GO:0007528 | neuromuscular junction development(GO:0007528) |
0.2 | 0.6 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.0 | 0.5 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.0 | 0.5 | GO:0030388 | fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.0 | 0.5 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.0 | 0.5 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.1 | 0.4 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
0.1 | 0.4 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
0.1 | 0.4 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) |
0.0 | 0.4 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 27 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 5.0 | GO:0043196 | varicosity(GO:0043196) |
0.1 | 1.4 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 1.4 | GO:0005657 | replication fork(GO:0005657) |
0.2 | 1.3 | GO:0097433 | dense body(GO:0097433) |
0.0 | 1.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.8 | GO:0043034 | costamere(GO:0043034) |
0.1 | 0.7 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.7 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.0 | 0.6 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.2 | 0.5 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
0.1 | 0.5 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
0.0 | 0.5 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.5 | GO:0031527 | filopodium membrane(GO:0031527) |
0.1 | 0.3 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.1 | 0.3 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.1 | 0.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.3 | GO:0097452 | GAIT complex(GO:0097452) |
0.0 | 0.3 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
0.1 | 0.2 | GO:0034455 | t-UTP complex(GO:0034455) |
0.0 | 0.2 | GO:0030314 | junctional membrane complex(GO:0030314) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 49 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 5.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.3 | 1.4 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.2 | 1.3 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 1.3 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.1 | 1.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 0.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.0 | 0.9 | GO:0015485 | cholesterol binding(GO:0015485) |
0.2 | 0.7 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.1 | 0.6 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.1 | 0.6 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
0.1 | 0.5 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.1 | 0.5 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
0.0 | 0.5 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 0.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.5 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.5 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.5 | GO:0030552 | cAMP binding(GO:0030552) |
0.1 | 0.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.4 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.4 | GO:0070700 | BMP receptor binding(GO:0070700) |