Motif ID: Hif1a

Z-value: 0.615


Transcription factors associated with Hif1a:

Gene SymbolEntrez IDGene Name
Hif1a ENSMUSG00000021109.7 Hif1a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hif1amm10_v2_chr12_+_73907904_73907970-0.612.1e-03Click!


Activity profile for motif Hif1a.

activity profile for motif Hif1a


Sorted Z-values histogram for motif Hif1a

Sorted Z-values for motif Hif1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hif1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_46845832 1.392 ENSMUST00000048209.9
ENSMUST00000092621.4
Ldha

lactate dehydrogenase A

chr16_-_23988852 1.298 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr15_-_44788016 1.253 ENSMUST00000090057.4
ENSMUST00000110269.1
Sybu

syntabulin (syntaxin-interacting)

chr6_+_88724828 1.179 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr6_+_88724412 1.034 ENSMUST00000113585.2
Mgll
monoglyceride lipase
chr6_+_88724667 1.000 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr15_+_44787746 0.995 ENSMUST00000181839.1
2310069G16Rik
RIKEN cDNA 2310069G16 gene
chr6_+_88724489 0.895 ENSMUST00000113581.1
Mgll
monoglyceride lipase
chr6_+_88724462 0.879 ENSMUST00000113582.1
Mgll
monoglyceride lipase
chr13_-_52981027 0.870 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr17_-_27133620 0.590 ENSMUST00000118613.1
Uqcc2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr6_-_101377897 0.589 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr4_-_55532453 0.560 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr1_+_55088132 0.552 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr5_-_135251209 0.536 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr2_+_71873224 0.492 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr5_-_122779278 0.489 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr10_-_85102487 0.488 ENSMUST00000059383.6
Fhl4
four and a half LIM domains 4
chr1_-_153549697 0.472 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr9_+_21165714 0.469 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr14_-_18893749 0.461 ENSMUST00000150727.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr10_-_78009737 0.456 ENSMUST00000020522.8
Pfkl
phosphofructokinase, liver, B-type
chr2_-_14056029 0.418 ENSMUST00000074854.7
Ptpla
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr5_+_146948640 0.416 ENSMUST00000146511.1
ENSMUST00000132102.1
Gtf3a

general transcription factor III A

chr16_-_24393588 0.405 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr6_-_72958465 0.395 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr17_-_27133902 0.393 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr8_-_122551316 0.392 ENSMUST00000067252.7
Piezo1
piezo-type mechanosensitive ion channel component 1
chr2_-_14055963 0.390 ENSMUST00000091429.5
ENSMUST00000114753.1
Ptpla

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a

chr13_+_38345716 0.384 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr19_-_44069690 0.380 ENSMUST00000169092.1
Erlin1
ER lipid raft associated 1
chr12_-_79007276 0.377 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr9_-_35116804 0.376 ENSMUST00000034537.6
St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_+_74771886 0.368 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6
chr17_-_26201363 0.355 ENSMUST00000121959.1
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr4_-_129600642 0.352 ENSMUST00000102593.4
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr9_-_67760208 0.351 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr8_+_83997613 0.350 ENSMUST00000095228.3
Samd1
sterile alpha motif domain containing 1
chr1_+_120602405 0.349 ENSMUST00000079721.7
En1
engrailed 1
chr17_+_28769307 0.348 ENSMUST00000004986.6
Mapk13
mitogen-activated protein kinase 13
chr14_-_18893376 0.338 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr4_+_150236685 0.335 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr7_+_19004047 0.331 ENSMUST00000053713.3
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr13_+_118714678 0.329 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr8_+_64947177 0.328 ENSMUST00000079896.7
ENSMUST00000026595.5
Tmem192

transmembrane protein 192

chr11_+_54100924 0.319 ENSMUST00000093107.5
ENSMUST00000019050.5
ENSMUST00000174616.1
ENSMUST00000129499.1
ENSMUST00000126840.1
P4ha2




procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide




chr4_+_150236816 0.318 ENSMUST00000080926.6
Eno1
enolase 1, alpha non-neuron
chr5_+_100039990 0.317 ENSMUST00000169390.1
ENSMUST00000031268.6
Enoph1

enolase-phosphatase 1

chr14_-_18893623 0.313 ENSMUST00000177259.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr5_+_129020069 0.313 ENSMUST00000031383.7
ENSMUST00000111343.1
Ran

RAN, member RAS oncogene family

chr4_-_129600586 0.310 ENSMUST00000135055.1
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr7_-_68749170 0.294 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4

chr6_+_29272488 0.289 ENSMUST00000115289.1
ENSMUST00000054445.8
Hilpda

hypoxia inducible lipid droplet associated

chr14_+_5501674 0.284 ENSMUST00000181562.1
Gm3488
predicted gene, 3488
chr4_-_139352538 0.279 ENSMUST00000102503.3
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr19_+_18713225 0.276 ENSMUST00000055792.7
D030056L22Rik
RIKEN cDNA D030056L22 gene
chr2_-_163419508 0.274 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chr11_-_120348513 0.268 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr14_+_21052574 0.267 ENSMUST00000045376.9
Adk
adenosine kinase
chr4_-_139352298 0.266 ENSMUST00000030513.6
ENSMUST00000155257.1
Mrto4

MRT4, mRNA turnover 4, homolog (S. cerevisiae)

chr8_-_124949165 0.265 ENSMUST00000034469.5
Egln1
EGL nine homolog 1 (C. elegans)
chr17_-_46752170 0.265 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3

canopy 3 homolog (zebrafish)

chr4_+_152325831 0.260 ENSMUST00000103191.4
ENSMUST00000139685.1
Rpl22

ribosomal protein L22

chr2_+_30807826 0.260 ENSMUST00000041830.3
ENSMUST00000152374.1
Ntmt1

N-terminal Xaa-Pro-Lys N-methyltransferase 1

chr2_+_124089961 0.259 ENSMUST00000103241.1
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_+_31887262 0.249 ENSMUST00000138325.1
ENSMUST00000028187.6
Lamc3

laminin gamma 3

chr4_+_150237211 0.248 ENSMUST00000133839.1
Eno1
enolase 1, alpha non-neuron
chr3_-_58692391 0.248 ENSMUST00000070368.7
Siah2
seven in absentia 2
chr10_-_59951753 0.246 ENSMUST00000020308.3
Ddit4
DNA-damage-inducible transcript 4
chr11_+_78178651 0.242 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr8_+_106893616 0.238 ENSMUST00000047629.5
Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr6_-_125165707 0.237 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr11_-_96065350 0.232 ENSMUST00000100528.4
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
chr1_+_16665189 0.231 ENSMUST00000177501.1
ENSMUST00000065373.5
Tmem70

transmembrane protein 70

chr8_-_45999860 0.228 ENSMUST00000053558.9
Ankrd37
ankyrin repeat domain 37
chr12_+_105032638 0.223 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr11_-_120348475 0.222 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr4_-_133967953 0.222 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr11_-_89302545 0.212 ENSMUST00000061728.3
Nog
noggin
chrX_+_135993820 0.212 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr5_-_149051300 0.210 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr3_-_101110278 0.207 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr2_+_180119301 0.206 ENSMUST00000040668.8
Osbpl2
oxysterol binding protein-like 2
chr7_-_45466894 0.197 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr12_+_49385174 0.196 ENSMUST00000110746.1
3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr5_+_108694222 0.193 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr8_-_106893581 0.190 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
Chtf8



CTF8, chromosome transmission fidelity factor 8



chr14_+_4182576 0.190 ENSMUST00000164512.1
Gm2974
predicted gene 2974
chr5_+_125441546 0.187 ENSMUST00000049040.9
Bri3bp
Bri3 binding protein
chr6_+_125131869 0.187 ENSMUST00000044200.8
Nop2
NOP2 nucleolar protein
chr1_-_17097839 0.186 ENSMUST00000038382.4
Jph1
junctophilin 1
chr5_-_135064063 0.186 ENSMUST00000111205.1
ENSMUST00000141309.1
Wbscr22

Williams Beuren syndrome chromosome region 22

chr7_-_122067263 0.184 ENSMUST00000033159.3
Ears2
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr11_-_72489904 0.183 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr10_-_127180579 0.177 ENSMUST00000095270.2
Slc26a10
solute carrier family 26, member 10
chr1_+_9545397 0.177 ENSMUST00000072079.7
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr2_+_127336152 0.176 ENSMUST00000028846.6
Dusp2
dual specificity phosphatase 2
chr6_-_29212240 0.176 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chrX_-_93832106 0.174 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr11_-_120348091 0.172 ENSMUST00000106215.4
Actg1
actin, gamma, cytoplasmic 1
chr14_+_3572023 0.168 ENSMUST00000178728.1
Gm3005
predicted gene 3005
chr11_+_60537978 0.168 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr19_+_4510472 0.168 ENSMUST00000068004.6
Pcx
pyruvate carboxylase
chr15_-_93336800 0.166 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr6_-_70792155 0.164 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr11_-_87359011 0.163 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr15_-_31453564 0.162 ENSMUST00000110408.1
Ropn1l
ropporin 1-like
chr1_-_180256294 0.161 ENSMUST00000111108.3
Psen2
presenilin 2
chr8_-_116993459 0.160 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr14_-_18894255 0.158 ENSMUST00000124353.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr11_+_121259983 0.156 ENSMUST00000106113.1
Foxk2
forkhead box K2
chr6_-_101377342 0.155 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr5_-_124249758 0.155 ENSMUST00000162812.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr14_+_3332627 0.153 ENSMUST00000177786.1
Gm2956
predicted gene 2956
chr19_-_44069526 0.152 ENSMUST00000170801.1
Erlin1
ER lipid raft associated 1
chr17_+_46681038 0.147 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr7_+_16310412 0.142 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr13_+_90923122 0.141 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr7_+_3704025 0.140 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr14_+_3652030 0.140 ENSMUST00000167430.1
Gm3020
predicted gene 3020
chr11_-_102819663 0.139 ENSMUST00000092567.4
Gjc1
gap junction protein, gamma 1
chr3_+_108186332 0.137 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
Amigo1



adhesion molecule with Ig like domain 1



chr2_+_27515157 0.136 ENSMUST00000113952.3
Wdr5
WD repeat domain 5
chr19_-_44069736 0.136 ENSMUST00000172041.1
ENSMUST00000071698.6
ENSMUST00000112028.3
Erlin1


ER lipid raft associated 1


chr14_+_4726775 0.134 ENSMUST00000165619.1
Gm3252
predicted gene 3252
chr4_-_62519885 0.134 ENSMUST00000107444.1
ENSMUST00000030090.3
Alad

aminolevulinate, delta-, dehydratase

chr5_+_124112297 0.133 ENSMUST00000024470.6
ENSMUST00000119269.1
Ogfod2

2-oxoglutarate and iron-dependent oxygenase domain containing 2

chr10_+_80115779 0.129 ENSMUST00000003152.7
Stk11
serine/threonine kinase 11
chr7_-_100371889 0.125 ENSMUST00000032963.8
Ppme1
protein phosphatase methylesterase 1
chr6_+_85451488 0.124 ENSMUST00000032078.6
Cct7
chaperonin containing Tcp1, subunit 7 (eta)
chr1_-_75180349 0.123 ENSMUST00000027396.8
Abcb6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr5_-_149051604 0.122 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr14_+_4334763 0.120 ENSMUST00000165466.1
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr4_-_21685782 0.120 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr17_-_23677432 0.118 ENSMUST00000167059.1
ENSMUST00000024698.8
Tnfrsf12a

tumor necrosis factor receptor superfamily, member 12a

chr13_+_73604002 0.115 ENSMUST00000022102.7
Clptm1l
CLPTM1-like
chr5_-_33657889 0.115 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr14_-_6287250 0.115 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr1_+_120340569 0.112 ENSMUST00000037286.8
C1ql2
complement component 1, q subcomponent-like 2
chr11_+_117115133 0.112 ENSMUST00000021177.8
Sec14l1
SEC14-like 1 (S. cerevisiae)
chr8_-_69974367 0.109 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr7_-_109752210 0.106 ENSMUST00000128043.1
ENSMUST00000033333.6
Tmem9b

TMEM9 domain family, member B

chr15_+_101174096 0.106 ENSMUST00000000544.9
Acvr1b
activin A receptor, type 1B
chr8_-_106893515 0.105 ENSMUST00000176090.1
Chtf8
CTF8, chromosome transmission fidelity factor 8
chr15_-_75909289 0.103 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr6_+_49073795 0.102 ENSMUST00000128616.1
ENSMUST00000031839.6
ENSMUST00000114500.1
Malsu1


mitochondrial assembly of ribosomal large subunit 1


chr14_-_7174533 0.098 ENSMUST00000172431.1
Gm3512
predicted gene 3512
chr6_-_85451248 0.093 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr5_-_34187670 0.093 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr7_-_138909492 0.093 ENSMUST00000106112.1
Bnip3
BCL2/adenovirus E1B interacting protein 3
chr3_+_122245625 0.092 ENSMUST00000178826.1
Gclm
glutamate-cysteine ligase, modifier subunit
chr11_-_115491796 0.092 ENSMUST00000106530.1
ENSMUST00000021082.6
Nt5c

5',3'-nucleotidase, cytosolic

chr9_+_106203108 0.092 ENSMUST00000024047.5
Twf2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr7_+_122067164 0.092 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr10_+_36974536 0.092 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr5_+_135064206 0.089 ENSMUST00000071263.5
Dnajc30
DnaJ (Hsp40) homolog, subfamily C, member 30
chr2_+_27886416 0.089 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr15_-_75909319 0.088 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr19_+_45006475 0.084 ENSMUST00000026227.2
Peo1
progressive external ophthalmoplegia 1 (human)
chr10_-_80387642 0.081 ENSMUST00000062946.6
ENSMUST00000105350.1
Mex3d

mex3 homolog D (C. elegans)

chr18_+_35553401 0.080 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr16_+_20498817 0.080 ENSMUST00000003320.6
Eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr18_+_52465676 0.076 ENSMUST00000025406.7
Srfbp1
serum response factor binding protein 1
chr7_+_105736565 0.076 ENSMUST00000033182.3
Ilk
integrin linked kinase
chr15_-_75909543 0.074 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr4_-_11386757 0.073 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr14_-_70443219 0.072 ENSMUST00000180358.1
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr2_+_121140498 0.069 ENSMUST00000119031.1
ENSMUST00000110662.2
Adal

adenosine deaminase-like

chr1_+_63176818 0.068 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr7_+_105736702 0.067 ENSMUST00000163389.1
ENSMUST00000136687.1
Ilk

integrin linked kinase

chr14_-_7027449 0.060 ENSMUST00000170738.2
Gm10406
predicted gene 10406
chr11_-_77489666 0.058 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr14_-_89898466 0.057 ENSMUST00000081204.4
Gm10110
predicted gene 10110
chr17_-_46680870 0.049 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chr1_+_42952872 0.048 ENSMUST00000179766.1
Gpr45
G protein-coupled receptor 45
chr15_+_86058727 0.047 ENSMUST00000138134.1
Gramd4
GRAM domain containing 4
chr9_+_107569112 0.047 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr11_+_97315716 0.046 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr6_-_125165576 0.045 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr14_-_6889962 0.042 ENSMUST00000171906.1
Gm3667
predicted gene 3667
chr7_-_105736781 0.041 ENSMUST00000033179.6
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr10_+_17723220 0.040 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr5_-_144965793 0.035 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr2_+_121140407 0.035 ENSMUST00000028702.3
ENSMUST00000110665.1
Adal

adenosine deaminase-like

chr5_+_110653444 0.033 ENSMUST00000031478.5
Ddx51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr2_-_148875452 0.033 ENSMUST00000028938.6
ENSMUST00000144845.1
Cst3

cystatin C

chr19_-_45006385 0.031 ENSMUST00000097715.2
Mrpl43
mitochondrial ribosomal protein L43
chr7_+_28693032 0.029 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27

F-box protein 27

chr4_+_131873608 0.026 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr3_+_94954075 0.024 ENSMUST00000107260.2
ENSMUST00000142311.1
ENSMUST00000137088.1
ENSMUST00000152869.1
ENSMUST00000107254.1
ENSMUST00000107253.1
Rfx5





regulatory factor X, 5 (influences HLA class II expression)





chr11_+_3332426 0.024 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr14_-_19585135 0.022 ENSMUST00000170694.1
Gm2237
predicted gene 2237
chr10_-_79766872 0.022 ENSMUST00000047203.8
Rnf126
ring finger protein 126
chr10_+_43479140 0.021 ENSMUST00000167488.1
ENSMUST00000040147.7
Bend3

BEN domain containing 3

chr2_+_156840966 0.021 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr14_-_29721835 0.021 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr7_-_99182681 0.018 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr9_+_108347827 0.012 ENSMUST00000035237.6
Usp4
ubiquitin specific peptidase 4 (proto-oncogene)
chr11_-_72411695 0.012 ENSMUST00000108500.1
ENSMUST00000050226.6
Smtnl2

smoothelin-like 2

chr3_+_122245557 0.011 ENSMUST00000029769.7
Gclm
glutamate-cysteine ligase, modifier subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.3 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.3 1.4 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.3 0.3 GO:0033122 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.2 0.6 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.2 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 1.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 1.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.1 0.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.2 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1 0.4 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.1 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.5 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025)
0.0 0.1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206)
0.0 0.3 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0 0.2 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.7 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.0 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0014002 astrocyte development(GO:0014002)
0.0 1.3 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.3 GO:0018208 peptidyl-proline modification(GO:0018208)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 GO:0043196 varicosity(GO:0043196)
0.2 0.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.3 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 1.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.8 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.4 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 1.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 1.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0070883 importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883)
0.1 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0034547 GTP cyclohydrolase activity(GO:0003933) N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.0 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)