Motif ID: Tbx15

Z-value: 0.648


Transcription factors associated with Tbx15:

Gene SymbolEntrez IDGene Name
Tbx15 ENSMUSG00000027868.5 Tbx15



Activity profile for motif Tbx15.

activity profile for motif Tbx15


Sorted Z-values histogram for motif Tbx15

Sorted Z-values for motif Tbx15



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_48045144 3.395 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr4_+_125490688 2.280 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr6_+_108213086 1.711 ENSMUST00000032192.6
 Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr16_-_23988852 1.365 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr7_-_78577771 1.364 ENSMUST00000039438.7
 Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr4_-_129121889 1.357 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
 Hpca


hippocalcin


chr7_-_78578308 1.264 ENSMUST00000039431.7
 Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr15_+_103503261 1.207 ENSMUST00000023132.3
 Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr5_+_32136458 1.192 ENSMUST00000031017.9
 Fosl2
fos-like antigen 2
chr19_-_10304867 1.185 ENSMUST00000039327.4
 Dagla
diacylglycerol lipase, alpha
chr4_+_53440388 1.125 ENSMUST00000102911.3
ENSMUST00000107646.2
 Slc44a1

solute carrier family 44, member 1

chr8_-_8639363 1.010 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr17_-_81649607 1.001 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
 Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chrX_+_41401128 0.969 ENSMUST00000115103.2
 Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr8_+_84723003 0.916 ENSMUST00000098571.4
 G430095P16Rik
RIKEN cDNA G430095P16 gene
chr16_-_43979050 0.884 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr7_+_79810727 0.875 ENSMUST00000107394.1
 Mesp2
mesoderm posterior 2
chr6_+_115134899 0.826 ENSMUST00000009538.5
ENSMUST00000169345.1
 Syn2

synapsin II

chr4_+_53440516 0.812 ENSMUST00000107651.2
ENSMUST00000107647.1
 Slc44a1

solute carrier family 44, member 1

chr12_-_78980758 0.778 ENSMUST00000174072.1
 Tmem229b
transmembrane protein 229B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.4 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.9 2.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 2.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 1.9 GO:0015871 choline transport(GO:0015871)
0.6 1.8 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.3 1.7 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 1.6 GO:0001919 regulation of receptor recycling(GO:0001919)
0.7 1.4 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.4 1.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.2 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 1.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 1.0 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.0 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.2 0.9 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.8 GO:0035904 aorta development(GO:0035904)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 1.8 GO:0044327 dendritic spine head(GO:0044327)
0.6 1.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.2 1.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.4 GO:0043196 varicosity(GO:0043196)
0.0 1.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.3 0.9 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.1 0.4 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.5 2.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 2.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.5 1.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.6 1.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.2 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 1.2 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.2 0.9 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.2 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.8 GO:0030276 clathrin binding(GO:0030276)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)