Motif ID: Vsx2_Dlx3

Z-value: 1.596

Transcription factors associated with Vsx2_Dlx3:

Gene SymbolEntrez IDGene Name
Dlx3 ENSMUSG00000001510.7 Dlx3
Vsx2 ENSMUSG00000021239.6 Vsx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Vsx2mm10_v2_chr12_+_84569762_84569840-0.232.9e-01Click!


Activity profile for motif Vsx2_Dlx3.

activity profile for motif Vsx2_Dlx3


Sorted Z-values histogram for motif Vsx2_Dlx3

Sorted Z-values for motif Vsx2_Dlx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Vsx2_Dlx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 127 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 55.781 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr6_-_23248264 35.864 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr12_+_38780817 10.739 ENSMUST00000160856.1
 Etv1
ets variant gene 1
chr12_+_38780284 10.320 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr10_+_73821857 8.775 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
 Pcdh15



















protocadherin 15



















chr12_+_109545390 8.570 ENSMUST00000146701.1
 Meg3
maternally expressed 3
chr2_-_168767136 8.510 ENSMUST00000029061.5
ENSMUST00000103074.1
 Sall4

sal-like 4 (Drosophila)

chr3_-_116253467 8.258 ENSMUST00000090473.5
 Gpr88
G-protein coupled receptor 88
chr3_+_55782500 7.604 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr7_-_49636847 6.832 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr12_-_31713873 6.326 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
 Gpr22


G protein-coupled receptor 22


chr10_-_6980376 6.183 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr9_-_79977782 5.736 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr12_+_38781093 5.172 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr3_+_159839729 5.001 ENSMUST00000068952.5
 Wls
wntless homolog (Drosophila)
chr16_-_42340595 4.333 ENSMUST00000102817.4
 Gap43
growth associated protein 43
chr2_-_168767029 4.322 ENSMUST00000075044.3
 Sall4
sal-like 4 (Drosophila)
chr1_+_109983737 4.182 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2
chr17_+_43952999 4.152 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr4_+_62583568 3.789 ENSMUST00000098031.3
 Rgs3
regulator of G-protein signaling 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.0 55.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
6.3 37.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.8 26.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.7 12.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 9.3 GO:0019228 neuronal action potential(GO:0019228)
1.0 8.8 GO:0050957 equilibrioception(GO:0050957)
0.4 8.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.4 6.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 6.0 GO:1901652 response to peptide(GO:1901652)
0.4 5.0 GO:0031017 exocrine pancreas development(GO:0031017)
0.3 4.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.5 4.3 GO:0016198 axon choice point recognition(GO:0016198)
0.2 3.7 GO:0007530 sex determination(GO:0007530)
0.1 3.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 3.4 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.2 3.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.0 2.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.6 2.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 2.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.6 2.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 111.3 GO:0005634 nucleus(GO:0005634)
0.1 12.8 GO:0000792 heterochromatin(GO:0000792)
0.2 8.8 GO:0032420 stereocilium(GO:0032420)
0.1 5.0 GO:0032590 dendrite membrane(GO:0032590)
0.2 4.3 GO:0031527 filopodium membrane(GO:0031527)
0.2 3.4 GO:0044292 dendrite terminus(GO:0044292)
0.2 2.9 GO:0031045 dense core granule(GO:0031045)
0.1 2.5 GO:0002102 podosome(GO:0002102)
0.3 1.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.3 1.6 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.1 1.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.2 1.2 GO:0060091 kinocilium(GO:0060091)
0.2 1.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 1.2 GO:1990391 DNA repair complex(GO:1990391)
0.3 1.1 GO:0060187 cell pole(GO:0060187)
0.2 1.1 GO:0071437 invadopodium(GO:0071437)
0.1 1.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 69.2 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 63.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 11.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 8.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.5 5.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.7 4.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.7 4.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 3.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 3.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 3.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 2.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)
0.2 2.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 1.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 1.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 1.6 GO:0070728 leucine binding(GO:0070728)
0.1 1.5 GO:0042056 chemoattractant activity(GO:0042056)