Motif ID: Vsx2_Dlx3
Z-value: 1.596
Transcription factors associated with Vsx2_Dlx3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dlx3 | ENSMUSG00000001510.7 | Dlx3 |
Vsx2 | ENSMUSG00000021239.6 | Vsx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Vsx2 | mm10_v2_chr12_+_84569762_84569840 | -0.23 | 2.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
7.0 | 55.8 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
6.3 | 37.7 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
1.0 | 2.9 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
1.0 | 8.8 | GO:0050957 | equilibrioception(GO:0050957) |
0.8 | 26.2 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.7 | 12.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.6 | 2.9 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
0.6 | 2.3 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.5 | 1.6 | GO:0090526 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.5 | 4.3 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.5 | 2.3 | GO:2000065 | negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065) |
0.4 | 1.2 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.4 | 5.0 | GO:0031017 | exocrine pancreas development(GO:0031017) |
0.4 | 6.8 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
0.4 | 8.6 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.4 | 1.1 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
0.4 | 1.1 | GO:2000508 | regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.3 | 1.0 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
0.3 | 1.1 | GO:0032512 | regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.3 | 0.8 | GO:0021759 | globus pallidus development(GO:0021759) |
0.3 | 4.4 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.2 | 1.4 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.2 | 3.7 | GO:0007530 | sex determination(GO:0007530) |
0.2 | 3.2 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.2 | 1.8 | GO:0043129 | surfactant homeostasis(GO:0043129) |
0.2 | 9.3 | GO:0019228 | neuronal action potential(GO:0019228) |
0.2 | 2.5 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.2 | 1.0 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.2 | 1.1 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.1 | 0.4 | GO:0007525 | somatic muscle development(GO:0007525) |
0.1 | 1.2 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.1 | 0.9 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
0.1 | 0.9 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 1.6 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.1 | 0.3 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
0.1 | 0.3 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
0.1 | 2.1 | GO:0009409 | response to cold(GO:0009409) |
0.1 | 3.4 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.1 | 1.1 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.1 | 1.4 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.1 | 0.4 | GO:0032782 | urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918) |
0.1 | 0.6 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.0 | 0.3 | GO:0061368 | behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.0 | 1.6 | GO:0061028 | establishment of endothelial barrier(GO:0061028) |
0.0 | 1.7 | GO:0051693 | actin filament capping(GO:0051693) |
0.0 | 1.7 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
0.0 | 1.2 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.0 | 3.4 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
0.0 | 6.0 | GO:1901652 | response to peptide(GO:1901652) |
0.0 | 0.4 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 1.5 | GO:0045786 | negative regulation of cell cycle(GO:0045786) |
0.0 | 0.9 | GO:0022900 | electron transport chain(GO:0022900) |
0.0 | 0.5 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
0.0 | 0.6 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.0 | 0.2 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
0.0 | 0.3 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.0 | 1.2 | GO:0000077 | DNA damage checkpoint(GO:0000077) |
0.0 | 0.9 | GO:0008344 | adult locomotory behavior(GO:0008344) |
0.0 | 0.7 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.7 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.3 | 1.1 | GO:0060187 | cell pole(GO:0060187) |
0.3 | 1.6 | GO:0061689 | paranodal junction(GO:0033010) tricellular tight junction(GO:0061689) |
0.2 | 3.4 | GO:0044292 | dendrite terminus(GO:0044292) |
0.2 | 1.1 | GO:0071437 | invadopodium(GO:0071437) |
0.2 | 8.8 | GO:0032420 | stereocilium(GO:0032420) |
0.2 | 4.3 | GO:0031527 | filopodium membrane(GO:0031527) |
0.2 | 1.2 | GO:0060091 | kinocilium(GO:0060091) |
0.2 | 1.2 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
0.2 | 2.9 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 1.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.1 | 5.0 | GO:0032590 | dendrite membrane(GO:0032590) |
0.1 | 1.1 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
0.1 | 0.7 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.1 | 2.5 | GO:0002102 | podosome(GO:0002102) |
0.1 | 12.8 | GO:0000792 | heterochromatin(GO:0000792) |
0.1 | 0.6 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
0.1 | 1.1 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.1 | 1.5 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.1 | 0.3 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.1 | 0.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 0.5 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 1.2 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.3 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.1 | GO:0045252 | dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 0.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 111.3 | GO:0005634 | nucleus(GO:0005634) |
0.0 | 1.1 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.9 | GO:0070469 | respiratory chain(GO:0070469) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 4.4 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.7 | 4.3 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.5 | 5.0 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
0.3 | 1.6 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.3 | 1.6 | GO:0070728 | leucine binding(GO:0070728) |
0.3 | 3.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.2 | 1.0 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.2 | 2.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.2 | 0.6 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.2 | 1.8 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.2 | 1.7 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.2 | 3.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.2 | 2.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.2 | 1.1 | GO:0034452 | dynactin binding(GO:0034452) |
0.2 | 63.5 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.1 | 3.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 1.1 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 1.4 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.9 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
0.1 | 1.2 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
0.1 | 69.2 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
0.1 | 2.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 1.5 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.1 | 0.4 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.1 | 0.4 | GO:0015265 | urea channel activity(GO:0015265) |
0.1 | 8.8 | GO:0047485 | protein N-terminus binding(GO:0047485) |
0.1 | 11.2 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.1 | 3.4 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.0 | 0.3 | GO:0000150 | recombinase activity(GO:0000150) |
0.0 | 0.9 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 1.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 1.0 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
0.0 | 0.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 0.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.1 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 1.2 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
0.0 | 0.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 2.4 | GO:0000287 | magnesium ion binding(GO:0000287) |