Motif ID: Gmeb2

Z-value: 0.998


Transcription factors associated with Gmeb2:

Gene SymbolEntrez IDGene Name
Gmeb2 ENSMUSG00000038705.7 Gmeb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb2mm10_v2_chr2_-_181288016_1812880410.272.2e-01Click!


Activity profile for motif Gmeb2.

activity profile for motif Gmeb2


Sorted Z-values histogram for motif Gmeb2

Sorted Z-values for motif Gmeb2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb2

PNG image of the network

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Top targets:


Showing 1 to 20 of 187 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_101419696 2.985 ENSMUST00000131397.1
ENSMUST00000133055.1
 Ak4

adenylate kinase 4

chr4_+_101419277 2.307 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
 Ak4


adenylate kinase 4


chr15_+_82016420 2.071 ENSMUST00000168581.1
ENSMUST00000170630.1
ENSMUST00000164779.1
 Xrcc6


X-ray repair complementing defective repair in Chinese hamster cells 6


chr15_-_78544345 2.023 ENSMUST00000053239.2
 Sstr3
somatostatin receptor 3
chr14_-_45219364 1.884 ENSMUST00000022377.4
ENSMUST00000143609.1
ENSMUST00000139526.1
 Txndc16


thioredoxin domain containing 16


chr1_-_77515048 1.781 ENSMUST00000027451.6
 Epha4
Eph receptor A4
chr7_+_66839726 1.498 ENSMUST00000098382.3
 Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr7_+_66839752 1.476 ENSMUST00000107478.1
 Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr5_-_31291026 1.448 ENSMUST00000041565.7
 Ift172
intraflagellar transport 172
chr15_-_98677451 1.446 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
 Rnd1


Rho family GTPase 1


chr15_+_82016369 1.411 ENSMUST00000069530.6
 Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr15_-_50889691 1.392 ENSMUST00000165201.2
ENSMUST00000184458.1
 Trps1

trichorhinophalangeal syndrome I (human)

chr6_-_39725193 1.352 ENSMUST00000101497.3
 Braf
Braf transforming gene
chr12_+_102554966 1.333 ENSMUST00000021610.5
 Chga
chromogranin A
chr1_+_185454803 1.252 ENSMUST00000061093.6
 Slc30a10
solute carrier family 30, member 10
chr18_+_36281069 1.195 ENSMUST00000051301.3
 Pura
purine rich element binding protein A
chr1_-_161034794 1.134 ENSMUST00000177003.1
ENSMUST00000162226.2
ENSMUST00000159250.2
 Zbtb37


zinc finger and BTB domain containing 37


chr7_-_119896285 1.091 ENSMUST00000106519.1
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr7_+_27591705 1.087 ENSMUST00000167435.1
 Akt2
thymoma viral proto-oncogene 2
chr1_-_91459254 1.064 ENSMUST00000069620.8
 Per2
period circadian clock 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.3 GO:0046033 AMP metabolic process(GO:0046033)
0.9 3.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.7 2.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.4 GO:0010225 response to UV-C(GO:0010225)
0.0 2.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.3 2.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 2.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.6 1.8 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.2 1.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.4 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.4 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.4 1.3 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 1.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.1 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 1.0 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.9 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.6 3.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 2.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.0 GO:0060170 ciliary membrane(GO:0060170)
0.0 2.0 GO:0044295 axonal growth cone(GO:0044295)
0.3 1.8 GO:0000322 storage vacuole(GO:0000322)
0.1 1.4 GO:0097228 sperm principal piece(GO:0097228)
0.3 1.3 GO:0042583 chromaffin granule(GO:0042583)
0.1 1.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.2 0.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.7 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 0.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 5.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 4.7 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 2.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.7 2.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 1.8 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.4 1.8 GO:0042731 PH domain binding(GO:0042731)
0.1 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.1 GO:0043851 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 0.9 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 0.7 GO:0015562 efflux transmembrane transporter activity(GO:0015562) oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.7 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)