Motif ID: Nfe2l1_Mafg

Z-value: 1.262

Transcription factors associated with Nfe2l1_Mafg:

Gene SymbolEntrez IDGene Name
Mafg ENSMUSG00000051510.7 Mafg
Mafg ENSMUSG00000053906.4 Mafg
Nfe2l1 ENSMUSG00000038615.11 Nfe2l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafgmm10_v2_chr11_-_120633594_120633605-0.649.0e-04Click!
Nfe2l1mm10_v2_chr11_-_96829904_96829955-0.097.0e-01Click!


Activity profile for motif Nfe2l1_Mafg.

activity profile for motif Nfe2l1_Mafg


Sorted Z-values histogram for motif Nfe2l1_Mafg

Sorted Z-values for motif Nfe2l1_Mafg



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 27.668 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr7_-_137314394 7.100 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
 Ebf3



early B cell factor 3



chr17_+_93199348 6.189 ENSMUST00000064775.6
 Adcyap1
adenylate cyclase activating polypeptide 1
chr14_+_74640840 4.077 ENSMUST00000036653.3
 Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr9_-_79977782 3.959 ENSMUST00000093811.4
 Filip1
filamin A interacting protein 1
chr2_-_112480817 3.760 ENSMUST00000099589.2
 Chrm5
cholinergic receptor, muscarinic 5
chr8_+_31091593 3.547 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)
chr17_+_43952999 3.465 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr3_+_85915722 3.444 ENSMUST00000054148.7
 Gm9790
predicted gene 9790
chr7_-_74554474 3.201 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
 Slco3a1


solute carrier organic anion transporter family, member 3a1


chr4_+_101507855 3.118 ENSMUST00000038207.5
 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr12_+_38783503 3.001 ENSMUST00000159334.1
 Etv1
ets variant gene 1
chr12_-_10900296 3.000 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr12_+_38783455 2.812 ENSMUST00000161980.1
ENSMUST00000160701.1
 Etv1

ets variant gene 1

chr4_-_63403330 2.796 ENSMUST00000035724.4
 Akna
AT-hook transcription factor
chr18_-_62741387 2.761 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr18_-_47333311 2.593 ENSMUST00000126684.1
ENSMUST00000156422.1
 Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr15_+_101224207 2.459 ENSMUST00000000543.4
 Grasp
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr11_+_44617310 2.449 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr15_+_16778101 2.362 ENSMUST00000026432.6
 Cdh9
cadherin 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.6 27.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 7.5 GO:0007638 mechanosensory behavior(GO:0007638)
2.1 6.2 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.4 5.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
1.4 4.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 3.9 GO:0000077 DNA damage checkpoint(GO:0000077)
1.2 3.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.6 3.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 3.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.5 3.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.6 2.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 2.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 2.0 GO:0060539 diaphragm development(GO:0060539)
0.1 2.0 GO:0080111 DNA demethylation(GO:0080111)
0.4 1.9 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.2 1.9 GO:0031424 keratinization(GO:0031424)
0.1 1.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.6 1.8 GO:1900133 renin secretion into blood stream(GO:0002001) negative regulation of urine volume(GO:0035811) regulation of renin secretion into blood stream(GO:1900133)
0.3 1.8 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.8 GO:0043195 terminal bouton(GO:0043195)
0.1 4.9 GO:1990391 DNA repair complex(GO:1990391)
0.3 4.1 GO:0070852 cell body fiber(GO:0070852)
0.0 4.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 2.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 1.9 GO:0001533 cornified envelope(GO:0001533)
0.4 1.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 1.7 GO:0008623 CHRAC(GO:0008623)
0.1 1.5 GO:0043196 varicosity(GO:0043196)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 1.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 1.1 GO:0097440 apical dendrite(GO:0097440)
0.1 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.0 GO:0000502 proteasome complex(GO:0000502)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 29.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 14.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.4 6.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.7 5.0 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 4.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 4.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
1.0 4.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
1.3 3.8 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 3.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.2 3.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.6 3.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 2.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 2.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 2.0 GO:0015197 peptide transporter activity(GO:0015197)
0.1 2.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 1.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 1.8 GO:0051379 epinephrine binding(GO:0051379)