Motif ID: Rbpj
Z-value: 0.999
Transcription factors associated with Rbpj:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Rbpj | ENSMUSG00000039191.6 | Rbpj |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Rbpj | mm10_v2_chr5_+_53590453_53590574 | 0.08 | 7.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | GO:0060129 | BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) |
| 0.6 | 1.8 | GO:0046959 | habituation(GO:0046959) |
| 0.6 | 1.7 | GO:0003195 | tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.5 | 2.1 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
| 0.5 | 2.5 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) |
| 0.5 | 2.4 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.5 | 1.4 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 0.4 | 3.2 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.3 | 1.0 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.3 | 0.8 | GO:0031627 | telomeric loop formation(GO:0031627) |
| 0.3 | 2.7 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.3 | 1.1 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.3 | 1.5 | GO:0048597 | post-embryonic camera-type eye morphogenesis(GO:0048597) |
| 0.3 | 1.3 | GO:0015871 | choline transport(GO:0015871) regulation of resting membrane potential(GO:0060075) |
| 0.3 | 1.0 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
| 0.2 | 0.9 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.2 | 1.6 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) |
| 0.2 | 0.6 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 0.2 | 2.8 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.2 | 0.7 | GO:0019042 | viral latency(GO:0019042) |
| 0.1 | 1.8 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.1 | 1.4 | GO:0045056 | transcytosis(GO:0045056) |
| 0.1 | 1.7 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.5 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 0.1 | 0.5 | GO:0033030 | negative regulation of neutrophil apoptotic process(GO:0033030) |
| 0.1 | 1.7 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 1.8 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.1 | 0.4 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
| 0.1 | 0.5 | GO:0089700 | positive regulation of T cell receptor signaling pathway(GO:0050862) protein kinase D signaling(GO:0089700) |
| 0.1 | 0.9 | GO:0032570 | response to progesterone(GO:0032570) |
| 0.1 | 0.3 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.1 | 0.2 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
| 0.1 | 0.2 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) |
| 0.1 | 2.0 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.1 | 0.3 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.1 | 1.8 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.1 | 1.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.6 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 1.1 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.2 | GO:1903772 | regulation of viral budding via host ESCRT complex(GO:1903772) |
| 0.0 | 0.3 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.0 | 0.1 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.0 | 0.2 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.0 | 1.3 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.6 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.0 | 1.4 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.5 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.0 | 0.1 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.0 | 0.2 | GO:0061732 | mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732) |
| 0.0 | 2.7 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 0.2 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 0.7 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.2 | GO:0046477 | glycosylceramide catabolic process(GO:0046477) negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.0 | 0.3 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.6 | GO:0010831 | positive regulation of myotube differentiation(GO:0010831) |
| 0.0 | 0.3 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273) |
| 0.0 | 0.9 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 0.5 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 0.0 | GO:0036015 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) |
| 0.0 | 0.2 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 1.1 | GO:0048524 | positive regulation of viral process(GO:0048524) |
| 0.0 | 0.9 | GO:0050729 | positive regulation of inflammatory response(GO:0050729) |
| 0.0 | 0.0 | GO:0034310 | primary alcohol catabolic process(GO:0034310) |
| 0.0 | 0.0 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.3 | GO:0060632 | regulation of microtubule-based movement(GO:0060632) |
| 0.0 | 0.1 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 0.1 | GO:0051482 | positive regulation of collateral sprouting(GO:0048672) positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.0 | 0.3 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.0 | 0.2 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
| 0.0 | 0.5 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.5 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.4 | 1.3 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.3 | 2.0 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.3 | 1.1 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
| 0.2 | 1.6 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 1.8 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 1.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 3.8 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.2 | 0.7 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
| 0.1 | 0.9 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.1 | 1.7 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 1.2 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 0.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 1.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.7 | GO:0070688 | MLL5-L complex(GO:0070688) |
| 0.1 | 0.3 | GO:0031230 | intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203) |
| 0.1 | 0.2 | GO:0034455 | t-UTP complex(GO:0034455) |
| 0.1 | 0.5 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 0.6 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.9 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.2 | GO:0032127 | dense core granule membrane(GO:0032127) |
| 0.0 | 1.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.5 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.5 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 0.9 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.0 | 0.2 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.0 | 3.5 | GO:0044853 | plasma membrane raft(GO:0044853) |
| 0.0 | 0.2 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 1.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.5 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.3 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 1.3 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.2 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.1 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.0 | 0.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 0.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 2.5 | GO:0030133 | transport vesicle(GO:0030133) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.2 | GO:0038025 | reelin receptor activity(GO:0038025) |
| 0.6 | 1.7 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.5 | 2.7 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.4 | 2.5 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.3 | 1.5 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.3 | 1.4 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.3 | 2.1 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.2 | 2.4 | GO:0052872 | 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014) |
| 0.2 | 1.6 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.2 | 2.5 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 0.9 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.2 | 0.5 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.2 | 1.8 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.2 | 0.7 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.2 | 1.0 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.2 | 2.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.2 | 0.5 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958) |
| 0.1 | 1.1 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
| 0.1 | 1.3 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 0.4 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.1 | 0.8 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 0.7 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.1 | 0.9 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 0.7 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.2 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.1 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 0.9 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 0.4 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.1 | 0.6 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 1.8 | GO:0051119 | sugar transmembrane transporter activity(GO:0051119) |
| 0.0 | 0.2 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.0 | 1.3 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.6 | GO:0010181 | FMN binding(GO:0010181) |
| 0.0 | 0.2 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
| 0.0 | 0.7 | GO:0052890 | oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890) |
| 0.0 | 0.5 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 1.7 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.9 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.2 | GO:0004779 | sulfate adenylyltransferase activity(GO:0004779) |
| 0.0 | 0.5 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.1 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) |
| 0.0 | 0.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 0.3 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.0 | 0.2 | GO:1990188 | euchromatin binding(GO:1990188) |
| 0.0 | 0.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.1 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 0.9 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.3 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 1.0 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 2.9 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.2 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 1.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.0 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
| 0.0 | 0.1 | GO:0035497 | cAMP response element binding(GO:0035497) |
