Motif ID: Irx6_Irx2_Irx3

Z-value: 0.756

Transcription factors associated with Irx6_Irx2_Irx3:

Gene SymbolEntrez IDGene Name
Irx2 ENSMUSG00000001504.9 Irx2
Irx3 ENSMUSG00000031734.11 Irx3
Irx6 ENSMUSG00000031738.8 Irx6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Irx2mm10_v2_chr13_+_72632597_72632625-0.369.3e-02Click!
Irx6mm10_v2_chr8_+_92674289_92674289-0.096.8e-01Click!
Irx3mm10_v2_chr8_-_91801547_918015600.038.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Irx6_Irx2_Irx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_124493793 2.612 ENSMUST00000178787.1
Gm21836
predicted gene, 21836
chr1_+_45311538 2.253 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr8_+_84872105 1.805 ENSMUST00000136026.1
ENSMUST00000170296.1
Syce2

synaptonemal complex central element protein 2

chr18_+_35770318 1.699 ENSMUST00000165299.1
Gm16490
predicted gene 16490
chr12_-_74316394 1.464 ENSMUST00000110441.1
Gm11042
predicted gene 11042
chr11_-_26591729 1.232 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr10_+_61171954 1.225 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
Tbata


thymus, brain and testes associated


chr2_+_124089961 1.133 ENSMUST00000103241.1
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr7_-_79386943 1.125 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr17_+_17316078 1.062 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr6_-_48708206 1.016 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr7_-_103827922 1.007 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr14_-_30353468 0.989 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_-_112159034 0.985 ENSMUST00000033036.5
Dkk3
dickkopf homolog 3 (Xenopus laevis)
chr13_+_76579670 0.965 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr13_+_49504774 0.958 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr2_-_98667264 0.835 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr6_+_80019008 0.785 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr2_-_67433181 0.783 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr6_+_58833689 0.751 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr8_+_84908560 0.748 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr18_+_36664060 0.738 ENSMUST00000036765.7
Eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr11_+_43474276 0.687 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr13_+_73330982 0.686 ENSMUST00000022098.8
Mrpl36
mitochondrial ribosomal protein L36
chr16_-_77602094 0.673 ENSMUST00000114231.1
Gm11146
predicted gene 11146
chr10_-_29699379 0.661 ENSMUST00000092620.4
Gm10275
predicted pseudogene 10275
chr3_+_106034661 0.639 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr12_+_69963452 0.628 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr1_-_173942445 0.624 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr3_+_121291725 0.577 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr12_+_55124528 0.574 ENSMUST00000177768.1
Fam177a
family with sequence similarity 177, member A
chr14_-_31001311 0.571 ENSMUST00000161219.1
ENSMUST00000182501.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr6_+_138140521 0.547 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr6_-_56901870 0.546 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr6_-_131247342 0.535 ENSMUST00000032306.8
ENSMUST00000088867.6
Klra2

killer cell lectin-like receptor, subfamily A, member 2

chr13_+_16014457 0.529 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr1_+_194938821 0.496 ENSMUST00000016638.2
ENSMUST00000110815.2
Cd34

CD34 antigen

chr8_+_36489191 0.484 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr4_+_53826014 0.483 ENSMUST00000030127.6
Tmem38b
transmembrane protein 38B
chr4_-_96553617 0.477 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr6_-_3494587 0.441 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr1_-_195092242 0.439 ENSMUST00000162650.1
ENSMUST00000160817.1
ENSMUST00000162614.1
ENSMUST00000016637.6
Cd46



CD46 antigen, complement regulatory protein



chr14_+_31001414 0.439 ENSMUST00000022476.7
Glt8d1
glycosyltransferase 8 domain containing 1
chr16_-_52296924 0.438 ENSMUST00000167115.1
Alcam
activated leukocyte cell adhesion molecule
chr14_+_31001383 0.434 ENSMUST00000168584.1
Glt8d1
glycosyltransferase 8 domain containing 1
chr4_-_108118528 0.424 ENSMUST00000030340.8
Scp2
sterol carrier protein 2, liver
chr13_+_100669481 0.423 ENSMUST00000057325.7
ENSMUST00000170347.2
Ccdc125

coiled-coil domain containing 125

chr4_-_139131058 0.421 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr18_-_31820413 0.413 ENSMUST00000165131.2
Gm6665
predicted gene 6665
chr1_+_60181495 0.412 ENSMUST00000160834.1
Nbeal1
neurobeachin like 1
chr8_+_56551090 0.410 ENSMUST00000040218.5
ENSMUST00000110322.3
Fbxo8

F-box protein 8

chr16_-_36784924 0.397 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr2_+_173000114 0.397 ENSMUST00000029013.3
ENSMUST00000132212.1
Rae1

RAE1 RNA export 1 homolog (S. pombe)

chr5_-_117389029 0.393 ENSMUST00000111953.1
ENSMUST00000086461.6
Rfc5

replication factor C (activator 1) 5

chr7_+_19212521 0.391 ENSMUST00000060225.4
Gpr4
G protein-coupled receptor 4
chr9_+_50575273 0.389 ENSMUST00000059081.6
ENSMUST00000180021.1
Il18

interleukin 18

chr17_-_21933022 0.380 ENSMUST00000074295.7
Zfp942
zinc finger protein 942
chr1_+_140246216 0.372 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2



chr4_-_108118504 0.367 ENSMUST00000149106.1
Scp2
sterol carrier protein 2, liver
chr10_-_39122277 0.364 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chrX_+_106920618 0.363 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr18_+_37447641 0.362 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr6_+_41546730 0.360 ENSMUST00000103299.1
Trbc2
T cell receptor beta, constant 2
chr7_-_130547358 0.356 ENSMUST00000160289.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr2_-_52335134 0.355 ENSMUST00000075301.3
Neb
nebulin
chr2_+_133552159 0.347 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr15_-_35938186 0.346 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr9_-_108428484 0.327 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chr17_+_91236787 0.326 ENSMUST00000057074.8
Gm6741
predicted gene 6741
chr13_+_67779754 0.316 ENSMUST00000164936.2
ENSMUST00000181319.1
Zfp493

zinc finger protein 493

chr2_-_86347764 0.308 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr8_+_84908680 0.308 ENSMUST00000145292.1
Dnase2a
deoxyribonuclease II alpha
chr19_-_28967794 0.305 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr5_-_43981757 0.302 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr3_-_123672321 0.301 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr1_+_159737510 0.297 ENSMUST00000111669.3
Tnr
tenascin R
chr14_+_123659971 0.294 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr9_+_64173364 0.289 ENSMUST00000034966.7
Rpl4
ribosomal protein L4
chr14_+_53324632 0.281 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr8_+_53511695 0.280 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr19_-_12765447 0.278 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr5_+_110330697 0.272 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr9_+_115909455 0.269 ENSMUST00000119291.1
ENSMUST00000069651.6
Gadl1

glutamate decarboxylase-like 1

chr10_+_29313500 0.265 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr2_+_177768044 0.264 ENSMUST00000108942.3
Gm14322
predicted gene 14322
chr7_+_120842824 0.261 ENSMUST00000047875.8
Eef2k
eukaryotic elongation factor-2 kinase
chr6_-_28397999 0.257 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr8_+_84908731 0.255 ENSMUST00000134569.1
Dnase2a
deoxyribonuclease II alpha
chr6_-_136941887 0.253 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr15_-_3979432 0.249 ENSMUST00000022791.8
Fbxo4
F-box protein 4
chr10_+_63243785 0.249 ENSMUST00000020258.8
Herc4
hect domain and RLD 4
chr19_-_57118981 0.248 ENSMUST00000111528.1
ENSMUST00000111529.1
ENSMUST00000104902.2
Ablim1


actin-binding LIM protein 1


chr10_-_125328957 0.239 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr7_-_80324115 0.237 ENSMUST00000123189.1
Rccd1
RCC1 domain containing 1
chrX_-_139714481 0.231 ENSMUST00000183728.1
Gm15013
predicted gene 15013
chr7_+_140763739 0.229 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr17_-_25785533 0.228 ENSMUST00000140738.1
ENSMUST00000145053.1
ENSMUST00000138759.1
ENSMUST00000133071.1
ENSMUST00000077938.3
Haghl




hydroxyacylglutathione hydrolase-like




chr4_-_136898803 0.221 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr16_-_36784784 0.219 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr10_+_39732099 0.218 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr18_+_51117754 0.215 ENSMUST00000116639.2
Prr16
proline rich 16
chr6_-_88875035 0.213 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr2_-_169405435 0.212 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr15_+_99006056 0.210 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr10_-_58718210 0.208 ENSMUST00000169859.1
Gm17542
predicted gene, 17542
chr12_+_55199533 0.205 ENSMUST00000177978.1
1700047I17Rik2
RIKEN cDNA 1700047I17 gene 2
chrX_+_82948861 0.204 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr13_-_27582168 0.204 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chr11_-_109472611 0.202 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chrM_+_7759 0.202 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr6_-_106800051 0.201 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr13_+_63282142 0.198 ENSMUST00000159152.1
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr2_+_68117713 0.196 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr10_+_11609256 0.196 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr3_-_113577743 0.195 ENSMUST00000067980.5
Amy1
amylase 1, salivary
chr9_-_112232449 0.192 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr11_-_102897123 0.188 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr10_-_30655859 0.188 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chrM_+_8600 0.186 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr4_+_99194124 0.186 ENSMUST00000180278.1
Atg4c
autophagy related 4C, cysteine peptidase
chr16_+_38742254 0.183 ENSMUST00000023482.6
ENSMUST00000114712.1
B4galt4

UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4

chr8_+_129118043 0.179 ENSMUST00000108744.1
1700008F21Rik
RIKEN cDNA 1700008F21 gene
chr3_-_120886691 0.179 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr11_-_68927049 0.177 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr5_-_134614953 0.177 ENSMUST00000036362.6
ENSMUST00000077636.4
Lat2

linker for activation of T cells family, member 2

chrX_+_56454871 0.175 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr10_-_100589205 0.172 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr2_-_169587745 0.168 ENSMUST00000109160.2
Gm11011
predicted gene 11011
chr3_+_105973711 0.167 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chrM_+_3906 0.166 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr13_-_77131276 0.164 ENSMUST00000159300.1
Ankrd32
ankyrin repeat domain 32
chr8_+_88697022 0.164 ENSMUST00000043526.8
Cyld
cylindromatosis (turban tumor syndrome)
chr12_+_17924294 0.163 ENSMUST00000169657.1
B430203G13Rik
RIKEN cDNA B430203G13 gene
chr10_-_19907545 0.163 ENSMUST00000134220.1
Pex7
peroxisomal biogenesis factor 7
chr12_-_48559971 0.162 ENSMUST00000169406.1
Gm1818
predicted gene 1818
chr1_+_52630692 0.162 ENSMUST00000165859.1
Tmem194b
transmembrane protein 194B
chr5_+_75152274 0.160 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr8_+_34154563 0.160 ENSMUST00000033933.5
Tmem66
transmembrane protein 66
chr8_-_105938384 0.158 ENSMUST00000034369.8
Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr18_-_12819842 0.158 ENSMUST00000119043.1
Osbpl1a
oxysterol binding protein-like 1A
chr3_+_97628804 0.155 ENSMUST00000107050.1
ENSMUST00000029729.8
ENSMUST00000107049.1
Fmo5


flavin containing monooxygenase 5


chr10_-_95324072 0.154 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr6_-_136941694 0.153 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr9_+_65346066 0.153 ENSMUST00000048184.2
Pdcd7
programmed cell death 7
chr10_+_24595623 0.152 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr3_-_36613285 0.151 ENSMUST00000108155.1
Bbs7
Bardet-Biedl syndrome 7 (human)
chr11_-_46166397 0.149 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chr18_-_67724560 0.148 ENSMUST00000120934.1
ENSMUST00000025420.7
ENSMUST00000122412.1
Ptpn2


protein tyrosine phosphatase, non-receptor type 2


chr7_+_110221697 0.148 ENSMUST00000033325.7
Swap70
SWA-70 protein
chr16_-_19706365 0.147 ENSMUST00000081880.5
Lamp3
lysosomal-associated membrane protein 3
chr10_+_84576626 0.147 ENSMUST00000020223.7
Tcp11l2
t-complex 11 (mouse) like 2
chr7_+_28350652 0.145 ENSMUST00000082134.4
Rps16
ribosomal protein S16
chr8_+_4625840 0.142 ENSMUST00000073201.5
Zfp958
zinc finger protein 958
chr4_-_98823840 0.141 ENSMUST00000097964.2
I0C0044D17Rik
RIKEN cDNA I0C0044D17 gene
chr10_+_127849917 0.140 ENSMUST00000077530.2
Rdh19
retinol dehydrogenase 19
chr2_-_93849921 0.138 ENSMUST00000111246.1
Accs
1-aminocyclopropane-1-carboxylate synthase (non-functional)
chr2_+_175283298 0.138 ENSMUST00000098998.3
Gm14440
predicted gene 14440
chr15_-_35938009 0.137 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr5_-_129623655 0.137 ENSMUST00000076842.5
Gm6139
predicted gene 6139
chr12_-_84617326 0.137 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr17_+_40811089 0.136 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr10_+_82378593 0.134 ENSMUST00000165906.1
Gm4924
predicted gene 4924
chr1_+_4857760 0.134 ENSMUST00000081551.7
Tcea1
transcription elongation factor A (SII) 1
chr4_+_129335593 0.134 ENSMUST00000141235.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chrX_+_56346390 0.130 ENSMUST00000101560.3
Zfp449
zinc finger protein 449
chr16_+_32419696 0.129 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1d2

Tctex1 domain containing 2

chr4_+_21727695 0.129 ENSMUST00000065928.4
Ccnc
cyclin C
chr9_-_54950954 0.128 ENSMUST00000054018.5
AY074887
cDNA sequence AY074887
chr1_+_59684949 0.127 ENSMUST00000027174.3
Nop58
NOP58 ribonucleoprotein
chr1_+_171840607 0.127 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr7_+_143052739 0.126 ENSMUST00000037941.9
Cd81
CD81 antigen
chr17_-_25785324 0.124 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr6_-_86684510 0.123 ENSMUST00000001186.4
ENSMUST00000113683.1
Snrnp27

small nuclear ribonucleoprotein 27 (U4/U6.U5)

chr2_-_175327598 0.123 ENSMUST00000109050.2
Gm4631
predicted gene 4631
chr1_-_179546261 0.122 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr4_+_119195496 0.122 ENSMUST00000097908.3
Ccdc23
coiled-coil domain containing 23
chr2_+_69790968 0.121 ENSMUST00000180290.1
Phospho2
phosphatase, orphan 2
chr4_-_116075022 0.121 ENSMUST00000050580.4
ENSMUST00000078676.5
Uqcrh

ubiquinol-cytochrome c reductase hinge protein

chr18_-_79109391 0.119 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chr8_+_104250869 0.119 ENSMUST00000034342.5
Cklf
chemokine-like factor
chr6_+_142414012 0.118 ENSMUST00000141548.1
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr2_-_175131864 0.113 ENSMUST00000108929.2
Gm14399
predicted gene 14399
chr5_-_148928619 0.111 ENSMUST00000149169.1
ENSMUST00000047257.8
Katnal1

katanin p60 subunit A-like 1

chr9_-_124311750 0.109 ENSMUST00000177714.1
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr6_+_79818031 0.109 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chrX_-_113185485 0.108 ENSMUST00000026607.8
ENSMUST00000113388.2
Chm

choroidermia

chr9_-_22071345 0.107 ENSMUST00000179605.1
ENSMUST00000043922.6
Zfp653

zinc finger protein 653

chr2_+_176431829 0.106 ENSMUST00000172025.1
Gm14435
predicted gene 14435
chr17_+_21733704 0.106 ENSMUST00000183192.1
ENSMUST00000065871.7
Zfp229

zinc finger protein 229

chr6_+_6863269 0.106 ENSMUST00000160937.2
ENSMUST00000171311.1
Dlx6

distal-less homeobox 6

chr5_-_100674230 0.106 ENSMUST00000031262.7
Coq2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr4_+_129336012 0.106 ENSMUST00000119480.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr14_+_44102654 0.105 ENSMUST00000074839.6
Ear2
eosinophil-associated, ribonuclease A family, member 2
chr1_+_10039762 0.105 ENSMUST00000122156.1
ENSMUST00000118263.1
ENSMUST00000119714.1
Cspp1


centrosome and spindle pole associated protein 1


chr19_-_32466575 0.105 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr6_-_118139094 0.104 ENSMUST00000049344.8
Csgalnact2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr19_+_53140430 0.102 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr4_+_119195353 0.102 ENSMUST00000106345.2
Ccdc23
coiled-coil domain containing 23
chr5_+_137758133 0.101 ENSMUST00000141733.1
ENSMUST00000110985.1
Tsc22d4

TSC22 domain family, member 4

chr18_+_37518341 0.100 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.3 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.2 0.8 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.2 0.5 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 0.6 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.4 GO:0043379 memory T cell differentiation(GO:0043379)
0.1 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.1 0.4 GO:0001866 NK T cell proliferation(GO:0001866) regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819)
0.1 0.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 1.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.5 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.3 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 1.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.3 GO:0048143 astrocyte activation(GO:0048143)
0.1 1.0 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus vasculature development(GO:0072239)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0038161 interleukin-4-mediated signaling pathway(GO:0035771) prolactin signaling pathway(GO:0038161) tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.0 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.8 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.7 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 1.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.7 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629) regulation of cell-cell adhesion mediated by integrin(GO:0033632) positive regulation of mast cell chemotaxis(GO:0060754) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.4 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.2 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) cellular response to copper ion(GO:0071280)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.1 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0061684 chaperone-mediated autophagy(GO:0061684)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0000801 central element(GO:0000801)
0.3 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.2 0.5 GO:0043512 inhibin A complex(GO:0043512)
0.2 2.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0072534 perineuronal net(GO:0072534)
0.1 0.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.3 1.0 GO:0070052 collagen V binding(GO:0070052)
0.3 1.0 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.8 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.2 1.1 GO:0019841 retinol binding(GO:0019841)
0.2 1.0 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 2.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.6 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.3 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.1 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 1.0 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.0 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)