Motif ID: Creb1

Z-value: 1.244


Transcription factors associated with Creb1:

Gene SymbolEntrez IDGene Name
Creb1 ENSMUSG00000025958.8 Creb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1mm10_v2_chr1_+_64532790_645328150.223.1e-01Click!


Activity profile for motif Creb1.

activity profile for motif Creb1


Sorted Z-values histogram for motif Creb1

Sorted Z-values for motif Creb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_4907705 2.075 ENSMUST00000020962.5
 Ubxn2a
UBX domain protein 2A
chr12_-_4907229 1.302 ENSMUST00000142867.1
 Ubxn2a
UBX domain protein 2A
chr15_+_66577536 1.251 ENSMUST00000048188.8
 Phf20l1
PHD finger protein 20-like 1
chr6_+_41605482 1.185 ENSMUST00000114732.2
 Ephb6
Eph receptor B6
chr1_+_185363076 1.150 ENSMUST00000046514.7
 Eprs
glutamyl-prolyl-tRNA synthetase
chr1_-_58973421 1.138 ENSMUST00000173590.1
ENSMUST00000027186.5
 Trak2

trafficking protein, kinesin binding 2

chr10_-_7792795 1.093 ENSMUST00000065124.1
 6530403G13Rik
RIKEN cDNA 6530403G13 gene
chr13_-_29984219 1.011 ENSMUST00000146092.1
 E2f3
E2F transcription factor 3
chr4_+_100776664 0.981 ENSMUST00000030257.8
ENSMUST00000097955.2
 Cachd1

cache domain containing 1

chr2_-_162661075 0.943 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
 Ptprt



protein tyrosine phosphatase, receptor type, T



chr19_-_55099417 0.903 ENSMUST00000061856.5
 Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr10_-_31609184 0.893 ENSMUST00000081989.6
 Rnf217
ring finger protein 217
chr12_+_116281180 0.876 ENSMUST00000100986.2
 Esyt2
extended synaptotagmin-like protein 2
chr11_+_116918844 0.869 ENSMUST00000103027.3
 Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr4_-_58553553 0.850 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
 Lpar1


lysophosphatidic acid receptor 1


chr11_-_83302586 0.814 ENSMUST00000176374.1
 Pex12
peroxisomal biogenesis factor 12
chr10_-_30618436 0.784 ENSMUST00000161074.1
 Hint3
histidine triad nucleotide binding protein 3
chr7_-_47008397 0.765 ENSMUST00000061639.7
 Spty2d1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr2_+_27886416 0.737 ENSMUST00000028280.7
 Col5a1
collagen, type V, alpha 1
chr4_-_58553311 0.732 ENSMUST00000107571.1
ENSMUST00000055018.4
 Lpar1

lysophosphatidic acid receptor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.5 1.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 1.4 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.3 1.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 1.2 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.4 1.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.2 1.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 0.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.9 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.3 0.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.0 0.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.7 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.2 0.6 GO:0070428 granuloma formation(GO:0002432) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 0.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.8 GO:0030139 endocytic vesicle(GO:0030139)
0.2 1.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.2 GO:0035869 ciliary transition zone(GO:0035869)
0.3 0.8 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 1.9 GO:0008374 O-acyltransferase activity(GO:0008374)
0.3 1.8 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.2 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.3 1.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 0.9 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.9 GO:0045294 alpha-catenin binding(GO:0045294) delta-catenin binding(GO:0070097)
0.1 0.8 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.7 GO:0097001 sphingolipid transporter activity(GO:0046624) ceramide binding(GO:0097001)
0.1 0.7 GO:0000182 rDNA binding(GO:0000182)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0005030 neurotrophin receptor activity(GO:0005030)