Motif ID: Tfap4

Z-value: 0.902


Transcription factors associated with Tfap4:

Gene SymbolEntrez IDGene Name
Tfap4 ENSMUSG00000005718.7 Tfap4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap4mm10_v2_chr16_-_4559720_45597470.472.3e-02Click!


Activity profile for motif Tfap4.

activity profile for motif Tfap4


Sorted Z-values histogram for motif Tfap4

Sorted Z-values for motif Tfap4



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_40346290 4.608 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr16_+_91269759 4.187 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr3_+_90537242 3.730 ENSMUST00000098911.3
 S100a16
S100 calcium binding protein A16
chr16_+_43510267 3.622 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr7_-_97417730 3.535 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr5_-_28210022 2.838 ENSMUST00000118882.1
 Cnpy1
canopy 1 homolog (zebrafish)
chr13_+_29014399 2.778 ENSMUST00000146336.1
ENSMUST00000130109.1
 A330102I10Rik

RIKEN cDNA A330102I10 gene

chr1_-_14310198 2.663 ENSMUST00000168081.2
ENSMUST00000027066.6
 Eya1

eyes absent 1 homolog (Drosophila)

chr3_+_90537306 2.492 ENSMUST00000107335.1
 S100a16
S100 calcium binding protein A16
chr4_+_119814495 2.461 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr2_+_170731807 2.345 ENSMUST00000029075.4
 Dok5
docking protein 5
chr7_-_120202104 2.174 ENSMUST00000033198.5
 Crym
crystallin, mu
chr8_+_66386292 2.047 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr5_+_90772435 2.042 ENSMUST00000031320.6
 Pf4
platelet factor 4
chrY_+_90843934 2.006 ENSMUST00000178550.1
 Gm21742
predicted gene, 21742
chr5_+_91517615 1.963 ENSMUST00000040576.9
 Parm1
prostate androgen-regulated mucin-like protein 1
chrX_+_169685191 1.751 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr19_-_8929323 1.676 ENSMUST00000096242.3
 Rom1
rod outer segment membrane protein 1
chr1_-_97977233 1.673 ENSMUST00000161567.1
 Pam
peptidylglycine alpha-amidating monooxygenase
chr3_+_5218516 1.615 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.0 GO:0051592 response to calcium ion(GO:0051592)
0.1 3.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 3.5 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 3.4 GO:0048663 neuron fate commitment(GO:0048663)
0.7 2.7 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 2.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 2.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.4 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 2.1 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.4 2.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of cytolysis(GO:0045918)
0.1 2.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 2.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 2.0 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.2 1.7 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.7 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.5 1.6 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.3 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.2 GO:0005770 late endosome(GO:0005770)
0.5 2.1 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.2 2.0 GO:0031091 platelet alpha granule(GO:0031091)
0.1 2.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.3 GO:0071564 npBAF complex(GO:0071564)
0.3 1.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.3 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.2 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.5 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 4.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 2.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 2.6 GO:0005158 insulin receptor binding(GO:0005158)
0.3 2.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 2.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.7 2.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 2.0 GO:0042287 MHC protein binding(GO:0042287)
0.6 1.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 1.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.5 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1 1.5 GO:0016151 nickel cation binding(GO:0016151)
0.3 1.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 1.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.0 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)