Motif ID: Mzf1

Z-value: 1.235


Transcription factors associated with Mzf1:

Gene SymbolEntrez IDGene Name
Mzf1 ENSMUSG00000030380.10 Mzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mzf1mm10_v2_chr7_-_13054665_13054764-0.511.3e-02Click!


Activity profile for motif Mzf1.

activity profile for motif Mzf1


Sorted Z-values histogram for motif Mzf1

Sorted Z-values for motif Mzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Mzf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 8.382 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_+_139543889 7.023 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr17_+_28142267 4.206 ENSMUST00000043503.3
 Scube3
signal peptide, CUB domain, EGF-like 3
chr11_-_100759942 4.199 ENSMUST00000107363.2
 Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr4_-_68954351 4.175 ENSMUST00000030036.5
 Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr7_-_34812677 4.118 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr9_-_97018823 4.066 ENSMUST00000055433.4
 Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr1_+_167001457 3.705 ENSMUST00000126198.1
 Fam78b
family with sequence similarity 78, member B
chr2_+_121295437 3.690 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr8_-_87959560 3.500 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr3_+_96596628 3.476 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr1_-_138842429 3.361 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr11_-_89302545 3.276 ENSMUST00000061728.3
 Nog
noggin
chr12_+_3891728 3.009 ENSMUST00000172689.1
ENSMUST00000111186.1
 Dnmt3a

DNA methyltransferase 3A

chr11_+_32276893 2.989 ENSMUST00000145569.1
 Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_-_100759740 2.943 ENSMUST00000107361.2
 Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr7_+_4925802 2.921 ENSMUST00000057612.7
 Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr9_+_119402444 2.903 ENSMUST00000035093.8
ENSMUST00000165044.1
 Acvr2b

activin receptor IIB

chr10_-_109010955 2.716 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr7_-_31051431 2.650 ENSMUST00000073892.4
 Fxyd7
FXYD domain-containing ion transport regulator 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 279 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 11.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 6.9 GO:2000821 regulation of grooming behavior(GO:2000821)
0.5 5.6 GO:0042711 maternal behavior(GO:0042711)
0.1 5.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
1.1 5.3 GO:0015671 oxygen transport(GO:0015671)
0.9 5.1 GO:0048318 axial mesoderm development(GO:0048318)
0.6 5.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 4.3 GO:0006284 base-excision repair(GO:0006284)
0.2 4.1 GO:0016486 peptide hormone processing(GO:0016486)
0.2 3.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 3.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.7 3.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.5 3.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 3.0 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.6 2.9 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 2.9 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 2.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 2.8 GO:0043171 peptide catabolic process(GO:0043171)
0.5 2.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.3 2.7 GO:0005513 detection of calcium ion(GO:0005513)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.1 GO:0005875 microtubule associated complex(GO:0005875)
0.3 6.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.6 4.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 4.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 3.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 3.5 GO:0005833 hemoglobin complex(GO:0005833)
0.0 3.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 3.4 GO:0005642 annulate lamellae(GO:0005642)
0.2 3.4 GO:0031045 dense core granule(GO:0031045)
0.1 3.2 GO:0071565 nBAF complex(GO:0071565)
0.1 3.0 GO:0001741 XY body(GO:0001741)
0.0 3.0 GO:0034399 nuclear periphery(GO:0034399)
0.1 2.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.9 GO:0005581 collagen trimer(GO:0005581)
0.3 2.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.5 GO:1990391 DNA repair complex(GO:1990391)
0.1 2.2 GO:0002102 podosome(GO:0002102)
0.2 2.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.6 1.9 GO:0044302 dentate gyrus mossy fiber(GO:0044302)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 193 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 7.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 5.8 GO:0005096 GTPase activator activity(GO:0005096)
0.1 5.4 GO:0045499 chemorepellent activity(GO:0045499)
1.1 5.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 4.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.5 4.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 4.2 GO:0005518 collagen binding(GO:0005518)
0.1 3.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.3 3.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 3.5 GO:0003779 actin binding(GO:0003779)
0.2 3.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 3.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.3 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 3.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.4 3.0 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 3.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 2.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 2.8 GO:0017070 U6 snRNA binding(GO:0017070)