Motif ID: Nfil3_Tef

Z-value: 1.466

Transcription factors associated with Nfil3_Tef:

Gene SymbolEntrez IDGene Name
Nfil3 ENSMUSG00000056749.7 Nfil3
Tef ENSMUSG00000022389.8 Tef

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tefmm10_v2_chr15_+_81811414_818114910.852.3e-07Click!
Nfil3mm10_v2_chr13_-_52981027_52981083-0.472.5e-02Click!


Activity profile for motif Nfil3_Tef.

activity profile for motif Nfil3_Tef


Sorted Z-values histogram for motif Nfil3_Tef

Sorted Z-values for motif Nfil3_Tef



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfil3_Tef

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_40346290 7.623 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr16_-_22439570 7.458 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr5_+_117841839 7.153 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr4_+_101419696 6.508 ENSMUST00000131397.1
ENSMUST00000133055.1
 Ak4

adenylate kinase 4

chr14_-_18239053 6.360 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr2_-_25469742 6.207 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr2_-_25470031 5.817 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chrX_-_51681856 5.400 ENSMUST00000114871.1
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr7_+_96211656 5.297 ENSMUST00000107165.1
 Tenm4
teneurin transmembrane protein 4
chrX_-_51681703 5.220 ENSMUST00000088172.5
 Hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr11_-_101785252 4.930 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr13_+_76579670 4.879 ENSMUST00000126960.1
ENSMUST00000109583.2
 Mctp1

multiple C2 domains, transmembrane 1

chr15_-_8710734 4.537 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_14310198 4.022 ENSMUST00000168081.2
ENSMUST00000027066.6
 Eya1

eyes absent 1 homolog (Drosophila)

chr1_-_91459254 4.011 ENSMUST00000069620.8
 Per2
period circadian clock 2
chr15_-_8710409 3.480 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_+_128846163 3.448 ENSMUST00000138291.1
 Gm12968
predicted gene 12968
chr6_-_40436104 3.396 ENSMUST00000039008.6
ENSMUST00000101492.3
 E330009J07Rik

RIKEN cDNA E330009J07 gene

chr7_-_103827922 3.328 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr3_+_51559973 2.920 ENSMUST00000180404.1
 5031434O11Rik
RIKEN cDNA 5031434O11 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 112 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 12.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
2.4 12.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.8 10.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.4 8.6 GO:0046033 AMP metabolic process(GO:0046033)
2.0 8.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.9 7.7 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
1.3 7.5 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.4 6.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 5.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
1.3 5.3 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.7 4.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.5 3.5 GO:0015862 uridine transport(GO:0015862)
0.3 3.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.6 2.9 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.6 2.8 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.5 2.8 GO:0048840 otolith development(GO:0048840)
0.0 2.8 GO:0007623 circadian rhythm(GO:0007623)
0.7 2.6 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.8 2.5 GO:0006116 NADH oxidation(GO:0006116)
0.3 2.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 8.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.5 8.0 GO:0043205 fibril(GO:0043205)
1.1 7.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.7 7.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 5.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 3.9 GO:0032993 protein-DNA complex(GO:0032993)
0.1 3.4 GO:0044298 cell body membrane(GO:0044298)
0.8 3.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 2.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 2.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 2.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 2.0 GO:0000805 X chromosome(GO:0000805)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.6 1.9 GO:0043512 inhibin A complex(GO:0043512)
0.4 1.9 GO:0030314 junctional membrane complex(GO:0030314)
0.2 1.5 GO:0042581 specific granule(GO:0042581)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 12.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.3 10.1 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
2.9 8.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.7 8.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
2.6 7.7 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 7.7 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 7.5 GO:0051787 misfolded protein binding(GO:0051787)
1.1 6.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 6.0 GO:0005509 calcium ion binding(GO:0005509)
0.2 3.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.8 3.3 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 3.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 2.7 GO:0031402 sodium ion binding(GO:0031402)
0.6 2.5 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.1 2.4 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.6 2.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.7 2.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 2.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 2.0 GO:0048487 beta-tubulin binding(GO:0048487)