Motif ID: Hoxb3
Z-value: 1.429
Transcription factors associated with Hoxb3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxb3 | ENSMUSG00000048763.5 | Hoxb3 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.3 | 17.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
1.1 | 5.7 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
1.1 | 4.5 | GO:0032788 | saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789) |
0.9 | 2.6 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.6 | 3.0 | GO:0030091 | protein repair(GO:0030091) |
0.4 | 1.3 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.4 | 1.5 | GO:1900272 | negative regulation of long-term synaptic potentiation(GO:1900272) |
0.3 | 3.5 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
0.3 | 8.7 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.2 | 1.2 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.2 | 0.6 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.2 | 1.8 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.2 | 1.6 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.2 | 0.5 | GO:0090403 | regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) regulation of fermentation(GO:0043465) oxidative stress-induced premature senescence(GO:0090403) negative regulation of fermentation(GO:1901003) |
0.2 | 1.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.2 | 1.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.2 | 1.0 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.2 | 0.5 | GO:0019085 | early viral transcription(GO:0019085) |
0.1 | 1.0 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
0.1 | 2.8 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
0.1 | 0.4 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
0.1 | 2.2 | GO:0048240 | sperm capacitation(GO:0048240) |
0.1 | 1.0 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.1 | 0.5 | GO:0015793 | glycerol transport(GO:0015793) |
0.1 | 2.6 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 1.3 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.1 | 1.1 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.1 | 1.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.6 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
0.1 | 1.7 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.1 | 1.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 0.4 | GO:0040031 | snRNA modification(GO:0040031) |
0.1 | 1.5 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.1 | 2.2 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.1 | 3.6 | GO:0048821 | erythrocyte development(GO:0048821) |
0.1 | 4.8 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
0.1 | 0.6 | GO:1902414 | protein localization to cell junction(GO:1902414) |
0.1 | 0.5 | GO:0060527 | prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527) |
0.1 | 1.1 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.1 | 0.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.2 | GO:0019532 | oxalate transport(GO:0019532) |
0.0 | 0.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.1 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
0.0 | 0.5 | GO:0070831 | basement membrane assembly(GO:0070831) |
0.0 | 3.4 | GO:0098792 | xenophagy(GO:0098792) |
0.0 | 1.6 | GO:0050729 | positive regulation of inflammatory response(GO:0050729) |
0.0 | 0.6 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.5 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 1.1 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
0.0 | 7.6 | GO:0032259 | methylation(GO:0032259) |
0.0 | 0.4 | GO:1901798 | positive regulation of signal transduction by p53 class mediator(GO:1901798) |
0.0 | 0.6 | GO:0006400 | tRNA modification(GO:0006400) |
0.0 | 0.6 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.6 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.0 | 0.1 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.0 | 0.4 | GO:0043330 | response to exogenous dsRNA(GO:0043330) |
0.0 | 1.3 | GO:0045580 | regulation of T cell differentiation(GO:0045580) |
0.0 | 2.1 | GO:0006275 | regulation of DNA replication(GO:0006275) |
0.0 | 0.1 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
0.0 | 1.0 | GO:0051209 | release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 17.3 | GO:0043205 | fibril(GO:0043205) |
0.9 | 3.6 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.2 | 1.0 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 2.0 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 3.1 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 1.6 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
0.1 | 2.8 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.1 | 2.5 | GO:0071565 | nBAF complex(GO:0071565) |
0.1 | 1.3 | GO:0005675 | holo TFIIH complex(GO:0005675) |
0.1 | 1.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.1 | 0.8 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.1 | 13.2 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 2.8 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 1.5 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.4 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.0 | 3.2 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 1.8 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.6 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 2.2 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 1.1 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 0.6 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 1.1 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.1 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.1 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.5 | 17.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.9 | 3.6 | GO:0031720 | haptoglobin binding(GO:0031720) |
0.7 | 8.2 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.7 | 3.5 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
0.3 | 1.0 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.3 | 1.5 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.3 | 3.0 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.3 | 4.5 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.2 | 1.0 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.2 | 2.6 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.2 | 2.6 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.2 | 1.6 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.2 | 1.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 3.5 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 2.2 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.1 | 1.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 1.0 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.1 | 0.5 | GO:0008410 | CoA-transferase activity(GO:0008410) |
0.1 | 0.5 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
0.1 | 2.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.7 | GO:0017040 | ceramidase activity(GO:0017040) |
0.1 | 0.6 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.1 | 0.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.5 | GO:0015265 | urea channel activity(GO:0015265) |
0.1 | 0.6 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
0.1 | 1.5 | GO:0042287 | MHC protein binding(GO:0042287) |
0.1 | 0.4 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
0.1 | 1.0 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.1 | 0.5 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 0.4 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 1.1 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.1 | 0.5 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
0.1 | 1.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 1.0 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 8.0 | GO:0008757 | S-adenosylmethionine-dependent methyltransferase activity(GO:0008757) |
0.0 | 1.3 | GO:0001221 | transcription cofactor binding(GO:0001221) |
0.0 | 1.6 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.0 | 0.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 1.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 1.1 | GO:0044824 | integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824) |
0.0 | 2.6 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 3.2 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 2.3 | GO:0044325 | ion channel binding(GO:0044325) |