Motif ID: Hoxb3

Z-value: 1.429


Transcription factors associated with Hoxb3:

Gene SymbolEntrez IDGene Name
Hoxb3 ENSMUSG00000048763.5 Hoxb3



Activity profile for motif Hoxb3.

activity profile for motif Hoxb3


Sorted Z-values histogram for motif Hoxb3

Sorted Z-values for motif Hoxb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 132 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_8710734 9.814 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_85722474 9.071 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr15_-_8710409 7.445 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_134932351 6.086 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
 Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr2_+_116067213 5.755 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr13_+_94083490 5.057 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr9_-_54661870 4.900 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr12_+_84069325 4.498 ENSMUST00000046422.4
ENSMUST00000072505.4
 Acot5

acyl-CoA thioesterase 5

chrX_+_170009892 4.070 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chr11_+_101665541 3.946 ENSMUST00000039388.2
 Arl4d
ADP-ribosylation factor-like 4D
chrY_+_90785442 3.586 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr11_+_32283511 3.562 ENSMUST00000093209.3
 Hba-a1
hemoglobin alpha, adult chain 1
chr19_+_3323301 3.483 ENSMUST00000025835.4
 Cpt1a
carnitine palmitoyltransferase 1a, liver
chr2_-_116067391 3.425 ENSMUST00000140185.1
 2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr12_-_83487708 3.422 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr9_-_54661666 3.298 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr14_-_64455903 3.193 ENSMUST00000067927.7
 Msra
methionine sulfoxide reductase A
chr12_-_25096080 3.139 ENSMUST00000020974.6
 Id2
inhibitor of DNA binding 2
chr10_-_83648631 2.834 ENSMUST00000146876.2
ENSMUST00000176294.1
 Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr8_+_66386292 2.768 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.3 17.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 8.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 7.6 GO:0032259 methylation(GO:0032259)
1.1 5.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 4.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
1.1 4.5 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 3.6 GO:0048821 erythrocyte development(GO:0048821)
0.3 3.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 3.4 GO:0098792 xenophagy(GO:0098792)
0.6 3.0 GO:0030091 protein repair(GO:0030091)
0.1 2.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.9 2.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 2.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.2 GO:0048240 sperm capacitation(GO:0048240)
0.1 2.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.1 GO:0006275 regulation of DNA replication(GO:0006275)
0.2 1.8 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 1.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 1.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 17.3 GO:0043205 fibril(GO:0043205)
0.1 13.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.9 3.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 3.2 GO:0072562 blood microparticle(GO:0072562)
0.1 3.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.8 GO:0031902 late endosome membrane(GO:0031902)
0.1 2.5 GO:0071565 nBAF complex(GO:0071565)
0.0 2.2 GO:0030496 midbody(GO:0030496)
0.1 2.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.8 GO:0070469 respiratory chain(GO:0070469)
0.1 1.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.2 1.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.5 17.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.7 8.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 8.0 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.3 4.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.9 3.6 GO:0031720 haptoglobin binding(GO:0031720)
0.7 3.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 3.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.2 GO:0004386 helicase activity(GO:0004386)
0.3 3.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2 2.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 2.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 2.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.3 GO:0044325 ion channel binding(GO:0044325)
0.1 2.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 1.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.3 1.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)