Motif ID: Foxm1

Z-value: 0.874


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_1283630580.772.0e-05Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 144 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_138842429 3.775 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chrX_-_141725181 3.441 ENSMUST00000067841.7
 Irs4
insulin receptor substrate 4
chr15_+_98167806 3.358 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr2_+_65845767 2.818 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_65845833 2.762 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr4_-_36136463 2.262 ENSMUST00000098151.2
 Lingo2
leucine rich repeat and Ig domain containing 2
chr8_+_34807287 2.245 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4
chr8_+_58912257 2.199 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr2_+_136052180 2.029 ENSMUST00000144403.1
 Lamp5
lysosomal-associated membrane protein family, member 5
chr12_-_40037387 1.807 ENSMUST00000146905.1
 Arl4a
ADP-ribosylation factor-like 4A
chr3_+_134828993 1.806 ENSMUST00000029822.4
 Tacr3
tachykinin receptor 3
chr19_-_58455161 1.779 ENSMUST00000135730.1
ENSMUST00000152507.1
 Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr9_-_100571049 1.735 ENSMUST00000093792.2
 Slc35g2
solute carrier family 35, member G2
chr19_-_58455398 1.692 ENSMUST00000026076.7
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_-_79440039 1.657 ENSMUST00000049972.4
 Scg2
secretogranin II
chr18_-_62741387 1.657 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr17_+_34305883 1.494 ENSMUST00000074557.8
 H2-Eb1
histocompatibility 2, class II antigen E beta
chr10_+_94576254 1.436 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chr19_-_58455903 1.434 ENSMUST00000131877.1
 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr19_+_25672408 1.264 ENSMUST00000053068.5
 Dmrt2
doublesex and mab-3 related transcription factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.9 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.8 3.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 2.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.2 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.2 1.8 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 1.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.3 1.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 1.7 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 1.5 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.3 1.3 GO:0061055 myotome development(GO:0061055)
0.4 1.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:0042551 neuron maturation(GO:0042551)
0.2 1.0 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.2 0.9 GO:0032901 positive regulation of neurotrophin production(GO:0032901)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 2.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 2.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.7 GO:0031045 dense core granule(GO:0031045)
0.2 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.3 GO:0016234 inclusion body(GO:0016234)
0.1 1.2 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0001652 granular component(GO:0001652)
0.1 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 4.0 GO:0005178 integrin binding(GO:0005178)
0.1 3.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 2.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 1.3 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.2 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.2 GO:0015250 water channel activity(GO:0015250)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0001848 complement binding(GO:0001848)
0.1 0.9 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.7 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)