Motif ID: Hmx1

Z-value: 0.638


Transcription factors associated with Hmx1:

Gene SymbolEntrez IDGene Name
Hmx1 ENSMUSG00000067438.3 Hmx1



Activity profile for motif Hmx1.

activity profile for motif Hmx1


Sorted Z-values histogram for motif Hmx1

Sorted Z-values for motif Hmx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_34005872 0.738 ENSMUST00000182296.1
 Dst
dystonin
chr15_-_13173607 0.568 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr5_-_34288407 0.538 ENSMUST00000114368.1
ENSMUST00000114369.1
 Zfyve28

zinc finger, FYVE domain containing 28

chr8_-_4217459 0.507 ENSMUST00000176227.1
 BC068157
cDNA sequence BC068157
chr15_-_85578070 0.506 ENSMUST00000109424.2
 Wnt7b
wingless-related MMTV integration site 7B
chr7_-_101921186 0.478 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
 Lrrc51


leucine rich repeat containing 51


chr6_-_148444336 0.469 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr15_+_60822947 0.436 ENSMUST00000180730.1
 9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr9_+_21184103 0.431 ENSMUST00000115458.2
 Pde4a
phosphodiesterase 4A, cAMP specific
chr5_+_121220191 0.422 ENSMUST00000119892.2
ENSMUST00000042614.6
 Gm15800

predicted gene 15800

chr6_+_58831456 0.416 ENSMUST00000141600.1
ENSMUST00000122981.1
 Herc3

hect domain and RLD 3

chr17_-_12769605 0.403 ENSMUST00000024599.7
 Igf2r
insulin-like growth factor 2 receptor
chr1_-_172057573 0.398 ENSMUST00000059794.3
 Nhlh1
nescient helix loop helix 1
chr6_-_127151044 0.391 ENSMUST00000000188.8
 Ccnd2
cyclin D2
chr17_+_48932368 0.385 ENSMUST00000046254.2
 Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr8_+_83389878 0.377 ENSMUST00000109831.2
 Clgn
calmegin
chr2_+_92915080 0.368 ENSMUST00000028648.2
 Syt13
synaptotagmin XIII
chr19_+_25610533 0.349 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr7_-_126160992 0.339 ENSMUST00000164741.1
 Xpo6
exportin 6
chr7_-_144939823 0.338 ENSMUST00000093962.4
 Ccnd1
cyclin D1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.2 0.5 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.1 0.5 GO:0070141 response to UV-A(GO:0070141)
0.0 0.5 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.4 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.3 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.7 GO:0031673 H zone(GO:0031673)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0034702 ion channel complex(GO:0034702) transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.2 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 0.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)