Motif ID: Sox5_Sry

Z-value: 1.482

Transcription factors associated with Sox5_Sry:

Gene SymbolEntrez IDGene Name
Sox5 ENSMUSG00000041540.10 Sox5
Sry ENSMUSG00000069036.3 Sry

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox5mm10_v2_chr6_-_143947061_1439470880.291.9e-01Click!


Activity profile for motif Sox5_Sry.

activity profile for motif Sox5_Sry


Sorted Z-values histogram for motif Sox5_Sry

Sorted Z-values for motif Sox5_Sry



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox5_Sry

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_17491216 5.335 ENSMUST00000080469.5
 Met
met proto-oncogene
chr11_+_94044111 4.896 ENSMUST00000132079.1
 Spag9
sperm associated antigen 9
chr1_+_34005872 4.627 ENSMUST00000182296.1
 Dst
dystonin
chr2_-_6722187 4.595 ENSMUST00000182657.1
 Celf2
CUGBP, Elav-like family member 2
chr7_-_115824699 3.312 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr4_-_82505707 3.109 ENSMUST00000107248.1
ENSMUST00000107247.1
 Nfib

nuclear factor I/B

chr5_+_66968559 2.987 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr2_-_60125651 2.919 ENSMUST00000112550.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr10_+_69706326 2.746 ENSMUST00000182992.1
 Ank3
ankyrin 3, epithelial
chr12_-_99393010 2.715 ENSMUST00000177451.1
 Foxn3
forkhead box N3
chr1_-_64121389 2.645 ENSMUST00000055001.3
 Klf7
Kruppel-like factor 7 (ubiquitous)
chr1_-_119837613 2.569 ENSMUST00000064091.5
 Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr18_+_69593361 2.210 ENSMUST00000114978.2
ENSMUST00000114977.1
 Tcf4

transcription factor 4

chr19_-_4334001 2.177 ENSMUST00000176653.1
 Kdm2a
lysine (K)-specific demethylase 2A
chr11_-_50292302 2.159 ENSMUST00000059458.4
 Maml1
mastermind like 1 (Drosophila)
chr2_-_6721890 2.133 ENSMUST00000114927.2
 Celf2
CUGBP, Elav-like family member 2
chr11_+_94044194 2.103 ENSMUST00000092777.4
ENSMUST00000075695.6
 Spag9

sperm associated antigen 9

chr3_+_101377074 1.914 ENSMUST00000043983.5
 Igsf3
immunoglobulin superfamily, member 3
chr7_-_37770757 1.806 ENSMUST00000176680.1
 Zfp536
zinc finger protein 536
chr3_+_127633134 1.768 ENSMUST00000029587.7
 Neurog2
neurogenin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 152 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 10.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.8 8.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 7.5 GO:0006376 mRNA splice site selection(GO:0006376)
1.6 6.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 6.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 4.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 4.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 3.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.3 3.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 3.4 GO:0042118 endothelial cell activation(GO:0042118)
0.2 3.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.4 3.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 2.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 2.3 GO:0048813 dendrite morphogenesis(GO:0048813)
0.7 2.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.7 2.2 GO:0003162 atrioventricular node development(GO:0003162)
0.3 2.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 2.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 2.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 1.9 GO:0032808 lacrimal gland development(GO:0032808)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 9.4 GO:0005667 transcription factor complex(GO:0005667)
0.4 8.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.3 6.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.2 4.6 GO:0031673 H zone(GO:0031673)
0.1 4.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 3.1 GO:0016459 myosin complex(GO:0016459)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.4 2.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 2.1 GO:0031430 M band(GO:0031430)
0.0 2.1 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 1.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.3 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.2 GO:0030478 actin cap(GO:0030478)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 82 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 11.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.8 10.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 9.4 GO:0003779 actin binding(GO:0003779)
0.2 6.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
1.3 5.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.7 5.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 4.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.9 4.3 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 3.8 GO:0018602 sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635)
0.2 3.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.4 2.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 2.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.2 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.9 GO:0070888 E-box binding(GO:0070888)
0.3 1.8 GO:0070697 activin receptor binding(GO:0070697)
0.1 1.8 GO:0030275 LRR domain binding(GO:0030275)
0.1 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 1.8 GO:0017091 AU-rich element binding(GO:0017091)