Motif ID: Wrnip1_Mta3_Rcor1

Z-value: 3.604

Transcription factors associated with Wrnip1_Mta3_Rcor1:

Gene SymbolEntrez IDGene Name
Mta3 ENSMUSG00000055817.11 Mta3
Rcor1 ENSMUSG00000037896.11 Rcor1
Wrnip1 ENSMUSG00000021400.6 Wrnip1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rcor1mm10_v2_chr12_+_111039334_111039400-0.812.2e-06Click!
Wrnip1mm10_v2_chr13_+_32802007_328021520.116.1e-01Click!
Mta3mm10_v2_chr17_+_83706137_83706169-0.048.6e-01Click!


Activity profile for motif Wrnip1_Mta3_Rcor1.

activity profile for motif Wrnip1_Mta3_Rcor1


Sorted Z-values histogram for motif Wrnip1_Mta3_Rcor1

Sorted Z-values for motif Wrnip1_Mta3_Rcor1



Network of associatons between targets according to the STRING database.



First level regulatory network of Wrnip1_Mta3_Rcor1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_115994953 17.448 ENSMUST00000015511.8
 Plxnd1
plexin D1
chr2_+_180499893 11.198 ENSMUST00000029084.2
 Ntsr1
neurotensin receptor 1
chr4_-_68954351 10.569 ENSMUST00000030036.5
 Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr4_+_138454305 9.670 ENSMUST00000050918.3
 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_+_36698002 9.447 ENSMUST00000021641.6
 Tshz3
teashirt zinc finger family member 3
chr7_+_123982799 9.354 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr7_+_43797567 7.676 ENSMUST00000085461.2
 Klk8
kallikrein related-peptidase 8
chr11_-_95587691 7.521 ENSMUST00000000122.6
 Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr15_-_66948419 7.460 ENSMUST00000167817.1
 Ndrg1
N-myc downstream regulated gene 1
chr7_-_34812677 7.390 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr18_-_38211957 7.356 ENSMUST00000159405.1
ENSMUST00000160721.1
 Pcdh1

protocadherin 1

chr12_+_112146187 7.027 ENSMUST00000128402.2
 Kif26a
kinesin family member 26A
chr9_-_110742577 6.932 ENSMUST00000006005.7
 Pth1r
parathyroid hormone 1 receptor
chr1_-_171196229 6.603 ENSMUST00000111332.1
 Pcp4l1
Purkinje cell protein 4-like 1
chr11_-_4746778 6.490 ENSMUST00000009219.2
 Cabp7
calcium binding protein 7
chr2_-_181156993 6.421 ENSMUST00000055990.7
 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr5_+_30588078 6.349 ENSMUST00000066295.2
 Kcnk3
potassium channel, subfamily K, member 3
chr2_-_151632471 6.182 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
 Snph






syntaphilin






chr7_-_31042078 6.061 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
 Fxyd5






FXYD domain-containing ion transport regulator 5






chr2_-_164857542 5.932 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
 Pltp



phospholipid transfer protein




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,324 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 21.2 GO:0009060 aerobic respiration(GO:0009060)
0.5 19.7 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.3 19.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.4 18.9 GO:0006414 translational elongation(GO:0006414)
0.7 18.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.9 16.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.6 16.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.8 15.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.4 14.8 GO:0022900 electron transport chain(GO:0022900)
1.3 14.0 GO:1900121 negative regulation of receptor binding(GO:1900121)
1.0 13.4 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.7 13.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
3.1 12.5 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
1.1 12.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8 12.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.6 12.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
2.0 12.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.2 12.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
2.3 11.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.4 11.7 GO:0033014 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 485 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 132.8 GO:1903561 extracellular vesicle(GO:1903561)
0.0 87.5 GO:0016021 integral component of membrane(GO:0016021)
0.1 65.4 GO:0005615 extracellular space(GO:0005615)
0.2 53.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.7 51.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 42.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 37.4 GO:0043204 perikaryon(GO:0043204)
0.0 35.9 GO:0005739 mitochondrion(GO:0005739)
0.7 35.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.6 29.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 27.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 26.6 GO:0005576 extracellular region(GO:0005576)
0.4 26.3 GO:0072562 blood microparticle(GO:0072562)
0.3 25.5 GO:0043195 terminal bouton(GO:0043195)
0.1 24.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.7 21.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.6 19.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.3 18.5 GO:0034705 potassium channel complex(GO:0034705)
0.5 18.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 17.5 GO:0043209 myelin sheath(GO:0043209)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 693 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 136.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 40.1 GO:0005525 GTP binding(GO:0005525)
0.3 36.4 GO:0016247 channel regulator activity(GO:0016247)
0.6 25.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 25.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.9 24.5 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.5 23.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
1.2 23.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.5 22.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 22.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.5 22.3 GO:0048487 beta-tubulin binding(GO:0048487)
1.0 18.3 GO:0015026 coreceptor activity(GO:0015026)
0.6 17.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 16.5 GO:0035254 glutamate receptor binding(GO:0035254)
0.7 16.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.7 15.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 15.7 GO:0030276 clathrin binding(GO:0030276)
0.5 15.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
1.1 14.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 14.2 GO:0030507 spectrin binding(GO:0030507)