Motif ID: Nr1h2

Z-value: 1.126


Transcription factors associated with Nr1h2:

Gene SymbolEntrez IDGene Name
Nr1h2 ENSMUSG00000060601.6 Nr1h2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1h2mm10_v2_chr7_-_44553901_445539550.845.6e-07Click!


Activity profile for motif Nr1h2.

activity profile for motif Nr1h2


Sorted Z-values histogram for motif Nr1h2

Sorted Z-values for motif Nr1h2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_53159885 8.504 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_-_97417730 7.316 ENSMUST00000043077.7
Thrsp
thyroid hormone responsive
chr11_-_60210410 5.313 ENSMUST00000144942.1
Srebf1
sterol regulatory element binding transcription factor 1
chr16_-_37384915 4.772 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr8_-_84773381 4.180 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr3_+_62419668 3.498 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr16_-_37384940 3.427 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr15_+_79895017 2.844 ENSMUST00000023054.7
Apobec3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chrX_-_102644210 2.755 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
Phka1





phosphorylase kinase alpha 1





chr5_-_124327883 2.647 ENSMUST00000031344.6
Mphosph9
M-phase phosphoprotein 9
chr7_+_97453204 2.483 ENSMUST00000050732.7
ENSMUST00000121987.1
Kctd14

potassium channel tetramerisation domain containing 14

chr2_-_113829069 2.470 ENSMUST00000024005.7
Scg5
secretogranin V
chr13_-_12461432 2.418 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
Lgals8



lectin, galactose binding, soluble 8



chr6_+_90462562 2.283 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr11_+_84179792 2.230 ENSMUST00000137500.2
ENSMUST00000130012.2
Acaca

acetyl-Coenzyme A carboxylase alpha

chr10_-_109823585 2.161 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr1_+_58711488 2.145 ENSMUST00000097722.2
ENSMUST00000114313.1
Cflar

CASP8 and FADD-like apoptosis regulator

chr11_+_84179852 2.093 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr13_+_44729794 2.044 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr17_-_79715034 1.887 ENSMUST00000024894.1
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr6_-_134632388 1.747 ENSMUST00000047443.3
Mansc1
MANSC domain containing 1
chr5_+_123015010 1.700 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr3_+_90514435 1.699 ENSMUST00000048138.6
ENSMUST00000181271.1
S100a13

S100 calcium binding protein A13

chr3_-_148989316 1.623 ENSMUST00000098518.2
Lphn2
latrophilin 2
chr7_+_114768736 1.575 ENSMUST00000117543.1
Insc
inscuteable homolog (Drosophila)
chr7_+_81523531 1.549 ENSMUST00000181903.1
2900076A07Rik
RIKEN cDNA 2900076A07 gene
chr2_-_33087169 1.502 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr5_+_76840597 1.405 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr2_+_131491764 1.392 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr18_+_37333853 1.384 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr7_-_133776681 1.379 ENSMUST00000130182.1
ENSMUST00000106139.1
Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chr5_-_136565432 1.370 ENSMUST00000176172.1
Cux1
cut-like homeobox 1
chr5_+_103754154 1.307 ENSMUST00000054979.3
Aff1
AF4/FMR2 family, member 1
chr2_-_26604267 1.269 ENSMUST00000028286.5
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr7_-_80371197 1.260 ENSMUST00000098346.3
Man2a2
mannosidase 2, alpha 2
chr2_+_30266721 1.254 ENSMUST00000113645.1
ENSMUST00000133877.1
ENSMUST00000139719.1
ENSMUST00000113643.1
ENSMUST00000150695.1
Phyhd1




phytanoyl-CoA dioxygenase domain containing 1




chr6_+_124663027 1.222 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr1_+_135729147 1.182 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr2_+_158306493 1.182 ENSMUST00000016168.2
ENSMUST00000109491.1
Lbp

lipopolysaccharide binding protein

chr7_+_81523555 1.165 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr16_+_96205719 1.121 ENSMUST00000129904.1
Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr4_-_141538562 1.102 ENSMUST00000105786.2
Spen
SPEN homolog, transcriptional regulator (Drosophila)
chr12_-_87147883 1.084 ENSMUST00000037788.4
Pomt2
protein-O-mannosyltransferase 2
chr2_-_126876209 1.072 ENSMUST00000103224.3
Trpm7
transient receptor potential cation channel, subfamily M, member 7
chr12_+_87147703 1.066 ENSMUST00000063117.8
Gstz1
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr1_+_57377593 1.040 ENSMUST00000042734.2
1700066M21Rik
RIKEN cDNA 1700066M21 gene
chr4_-_141538434 0.977 ENSMUST00000078886.3
Spen
SPEN homolog, transcriptional regulator (Drosophila)
chr7_+_27862557 0.970 ENSMUST00000053722.8
Zfp607
zinc finger proten 607
chr2_+_155382186 0.925 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr11_-_69948145 0.901 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr3_-_39359128 0.882 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chr7_+_112953955 0.851 ENSMUST00000182858.1
Rassf10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr1_+_6214627 0.825 ENSMUST00000027040.6
Rb1cc1
RB1-inducible coiled-coil 1
chr9_-_42472198 0.820 ENSMUST00000128959.1
ENSMUST00000066148.5
ENSMUST00000138506.1
Tbcel


tubulin folding cofactor E-like


chr5_+_124194894 0.799 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chr1_+_132506230 0.798 ENSMUST00000058167.1
Tmem81
transmembrane protein 81
chr17_-_56716788 0.769 ENSMUST00000067931.5
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr11_+_93996082 0.718 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr3_-_116424007 0.701 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr3_-_116423930 0.676 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr5_+_124328083 0.669 ENSMUST00000111477.1
ENSMUST00000077376.2
2810006K23Rik

RIKEN cDNA 2810006K23 gene

chr15_+_65787023 0.661 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
Efr3a



EFR3 homolog A (S. cerevisiae)



chr11_-_102556122 0.658 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr14_-_20730327 0.655 ENSMUST00000047490.5
Ndst2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr4_-_42168603 0.655 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr19_-_5845471 0.653 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr10_-_53638269 0.638 ENSMUST00000164393.1
Fam184a
family with sequence similarity 184, member A
chr5_-_120588613 0.609 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr8_+_4238815 0.602 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr10_+_18845071 0.594 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr4_+_123859651 0.594 ENSMUST00000097896.2
4933427I04Rik
Riken cDNA 4933427I04 gene
chr8_-_36249292 0.584 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr5_-_100159261 0.569 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr9_+_77941274 0.545 ENSMUST00000134072.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr15_-_89425795 0.531 ENSMUST00000168376.1
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr6_-_119544282 0.529 ENSMUST00000119369.1
ENSMUST00000178696.1
Wnt5b

wingless-related MMTV integration site 5B

chr4_-_119422355 0.529 ENSMUST00000106316.1
ENSMUST00000030385.6
Ppcs

phosphopantothenoylcysteine synthetase

chr11_-_30025915 0.523 ENSMUST00000058902.5
Eml6
echinoderm microtubule associated protein like 6
chr2_+_61593125 0.520 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chrX_-_155216338 0.513 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr12_-_111813834 0.507 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr8_+_71592158 0.506 ENSMUST00000034264.4
ENSMUST00000138742.1
ENSMUST00000143441.1
Pgls


6-phosphogluconolactonase


chr17_+_49428359 0.498 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
Mocs1


molybdenum cofactor synthesis 1


chr11_+_82952095 0.461 ENSMUST00000108158.2
ENSMUST00000067443.2
Slfn5

schlafen 5

chr8_+_4238733 0.458 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr2_+_154548888 0.457 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr10_-_81600857 0.442 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
Tle6


transducin-like enhancer of split 6, homolog of Drosophila E(spl)


chr15_+_85832301 0.433 ENSMUST00000146088.1
Ttc38
tetratricopeptide repeat domain 38
chr9_+_37208291 0.420 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr5_+_107331157 0.412 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr2_+_102658640 0.411 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_+_16870736 0.395 ENSMUST00000139740.1
ENSMUST00000119787.2
ENSMUST00000130650.1
ENSMUST00000156502.1
ENSMUST00000023465.7
ENSMUST00000124960.1
ENSMUST00000144513.1
Top3b






topoisomerase (DNA) III beta






chr1_-_164458345 0.388 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chrX_-_155216444 0.383 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr16_+_13940630 0.364 ENSMUST00000141971.1
ENSMUST00000124947.1
ENSMUST00000023360.7
ENSMUST00000143697.1
Mpv17l



Mpv17 transgene, kidney disease mutant-like



chr11_+_78245743 0.346 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr15_+_78877172 0.345 ENSMUST00000041587.7
Gga1
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr6_+_88902251 0.332 ENSMUST00000055022.8
Tpra1
transmembrane protein, adipocyte asscociated 1
chr11_+_55098104 0.318 ENSMUST00000000608.7
Gm2a
GM2 ganglioside activator protein
chr11_-_103697898 0.274 ENSMUST00000021329.7
Gosr2
golgi SNAP receptor complex member 2
chr7_+_67647405 0.271 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr17_-_25985641 0.266 ENSMUST00000041641.8
Capn15
calpain 15
chr15_-_83251720 0.255 ENSMUST00000164614.1
ENSMUST00000049530.6
A4galt

alpha 1,4-galactosyltransferase

chr16_-_38550173 0.247 ENSMUST00000036210.6
Poglut1
protein O-glucosyltransferase 1
chr16_+_16870829 0.242 ENSMUST00000131063.1
Top3b
topoisomerase (DNA) III beta
chr2_+_30266513 0.227 ENSMUST00000091132.6
Phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr19_+_53142756 0.208 ENSMUST00000050096.7
Add3
adducin 3 (gamma)
chr12_+_21286297 0.172 ENSMUST00000067284.8
Cpsf3
cleavage and polyadenylation specificity factor 3
chr15_+_76879232 0.160 ENSMUST00000023179.5
Zfp7
zinc finger protein 7
chrX_-_8175890 0.155 ENSMUST00000143984.1
Tbc1d25
TBC1 domain family, member 25
chr7_-_27446599 0.148 ENSMUST00000011895.7
Sptbn4
spectrin beta, non-erythrocytic 4
chr16_+_10835046 0.145 ENSMUST00000037913.8
Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr14_-_72602945 0.138 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr5_+_67306941 0.106 ENSMUST00000162372.1
ENSMUST00000113676.2
Slc30a9

solute carrier family 30 (zinc transporter), member 9

chr2_-_164911586 0.081 ENSMUST00000041361.7
Zfp335
zinc finger protein 335
chr5_+_130219706 0.072 ENSMUST00000065329.6
Tmem248
transmembrane protein 248
chr17_-_35897073 0.069 ENSMUST00000150056.1
ENSMUST00000156817.1
ENSMUST00000146451.1
ENSMUST00000148482.1
2310061I04Rik



RIKEN cDNA 2310061I04 gene



chr2_+_61593077 0.064 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr1_+_33719863 0.033 ENSMUST00000088287.3
Rab23
RAB23, member RAS oncogene family
chr7_-_19770509 0.020 ENSMUST00000003061.7
Bcam
basal cell adhesion molecule

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:0055099 regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
1.1 4.3 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.8 1.7 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.7 2.1 GO:0014891 striated muscle atrophy(GO:0014891)
0.7 5.3 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.6 1.9 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.6 1.2 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.5 2.8 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.5 2.3 GO:0046208 spermine catabolic process(GO:0046208)
0.4 2.4 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 1.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.4 1.4 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.4 1.1 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.3 4.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 7.3 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.3 1.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.2 0.7 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.2 2.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.4 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.2 8.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 0.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 0.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 2.3 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.2 3.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 1.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.4 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139)
0.1 2.5 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.6 GO:0002934 desmosome organization(GO:0002934)
0.1 1.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.6 GO:0006265 DNA topological change(GO:0006265)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.3 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.7 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 1.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0007141 male meiosis I(GO:0007141)
0.0 1.6 GO:0060487 lung epithelial cell differentiation(GO:0060487)
0.0 0.7 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 2.8 GO:0006073 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.5 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 2.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 1.4 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.4 2.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.8 GO:0045098 type III intermediate filament(GO:0045098)
0.2 0.5 GO:0097447 dendritic tree(GO:0097447)
0.2 0.7 GO:0001533 cornified envelope(GO:0001533)
0.1 7.4 GO:0031201 SNARE complex(GO:0031201)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 2.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.6 GO:0005776 autophagosome(GO:0005776)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188)
1.4 4.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.7 2.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.5 2.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 1.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.4 2.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 1.9 GO:0070330 aromatase activity(GO:0070330)
0.3 0.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 1.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.3 1.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 1.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 1.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.5 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 1.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 8.2 GO:0019905 syntaxin binding(GO:0019905)
0.1 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 2.0 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.3 GO:0044653 trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 2.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 6.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 2.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)