Motif ID: Nr1h2
Z-value: 1.126
Transcription factors associated with Nr1h2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr1h2 | ENSMUSG00000060601.6 | Nr1h2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr1h2 | mm10_v2_chr7_-_44553901_44553955 | 0.84 | 5.6e-07 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.1 | 8.5 | GO:0055099 | regulation of Cdc42 protein signal transduction(GO:0032489) response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155) |
1.1 | 4.3 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
0.8 | 1.7 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
0.7 | 2.1 | GO:0014891 | striated muscle atrophy(GO:0014891) |
0.7 | 5.3 | GO:0003062 | regulation of heart rate by chemical signal(GO:0003062) |
0.6 | 1.9 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
0.6 | 1.2 | GO:0097006 | regulation of plasma lipoprotein particle levels(GO:0097006) |
0.5 | 2.8 | GO:0010528 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
0.5 | 2.3 | GO:0046208 | spermine catabolic process(GO:0046208) |
0.4 | 2.4 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.4 | 1.2 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
0.4 | 1.4 | GO:0070589 | cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554) |
0.4 | 1.1 | GO:0006558 | L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) |
0.3 | 4.2 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.3 | 7.3 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
0.3 | 1.1 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
0.2 | 0.7 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
0.2 | 2.0 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.2 | 1.4 | GO:0000022 | mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256) |
0.2 | 8.2 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
0.2 | 0.5 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
0.2 | 0.7 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.2 | 2.3 | GO:0072010 | renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
0.2 | 3.5 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.2 | 1.3 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.1 | 0.4 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
0.1 | 0.5 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) resolution of recombination intermediates(GO:0071139) |
0.1 | 2.5 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.1 | 1.7 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.1 | 1.1 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
0.1 | 0.7 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.5 | GO:0051189 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.1 | 0.6 | GO:0002934 | desmosome organization(GO:0002934) |
0.1 | 1.3 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
0.1 | 0.6 | GO:0006265 | DNA topological change(GO:0006265) |
0.1 | 0.4 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.1 | 0.4 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.1 | 0.3 | GO:0006689 | ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313) |
0.1 | 0.3 | GO:0001575 | globoside metabolic process(GO:0001575) |
0.0 | 0.5 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.3 | GO:0040016 | embryonic cleavage(GO:0040016) |
0.0 | 0.8 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.7 | GO:0030575 | nuclear body organization(GO:0030575) |
0.0 | 0.5 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.2 | GO:0048318 | axial mesoderm development(GO:0048318) |
0.0 | 1.6 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.4 | GO:0007141 | male meiosis I(GO:0007141) |
0.0 | 1.6 | GO:0060487 | lung epithelial cell differentiation(GO:0060487) |
0.0 | 0.7 | GO:0071470 | cellular response to osmotic stress(GO:0071470) |
0.0 | 2.8 | GO:0006073 | glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042) |
0.0 | 0.2 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
0.0 | 0.1 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.0 | 0.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 1.5 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
0.0 | 1.2 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.5 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 8.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.4 | 2.8 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.4 | 1.4 | GO:0031502 | dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502) |
0.4 | 2.1 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.2 | 0.8 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.2 | 0.8 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.2 | 0.5 | GO:0097447 | dendritic tree(GO:0097447) |
0.2 | 0.7 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 7.4 | GO:0031201 | SNARE complex(GO:0031201) |
0.1 | 0.5 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.1 | 2.0 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 0.7 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 1.1 | GO:0043196 | varicosity(GO:0043196) |
0.1 | 0.4 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.1 | 0.9 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 2.6 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 1.3 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 1.4 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.1 | GO:0008091 | spectrin(GO:0008091) |
0.0 | 2.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 1.6 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.4 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.4 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.2 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 8.5 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) |
1.4 | 4.3 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.7 | 2.8 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
0.5 | 2.1 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.5 | 1.4 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
0.4 | 2.8 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
0.4 | 1.9 | GO:0070330 | aromatase activity(GO:0070330) |
0.3 | 0.9 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.3 | 1.2 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
0.3 | 1.7 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.2 | 0.9 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.2 | 1.4 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
0.2 | 1.2 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
0.2 | 0.6 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
0.2 | 0.5 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.1 | 1.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.1 | 0.7 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.1 | 0.6 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
0.1 | 0.5 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
0.1 | 0.4 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 0.7 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.1 | 0.5 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.1 | 0.2 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
0.1 | 8.2 | GO:0019905 | syntaxin binding(GO:0019905) |
0.1 | 0.3 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.1 | 0.7 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.1 | 1.1 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.1 | 2.0 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.1 | 1.3 | GO:0044653 | trehalase activity(GO:0015927) dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859) |
0.1 | 0.6 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 0.8 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 1.1 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.5 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.0 | 0.4 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.0 | 1.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
0.0 | 2.5 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 1.4 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 2.1 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 6.3 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 0.3 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 1.1 | GO:0005262 | calcium channel activity(GO:0005262) |
0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 2.4 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.0 | 0.5 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |