Motif ID: Sox4

Z-value: 0.839


Transcription factors associated with Sox4:

Gene SymbolEntrez IDGene Name
Sox4 ENSMUSG00000076431.4 Sox4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox4mm10_v2_chr13_-_28953690_289537130.737.5e-05Click!


Activity profile for motif Sox4.

activity profile for motif Sox4


Sorted Z-values histogram for motif Sox4

Sorted Z-values for motif Sox4



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox4

PNG image of the network

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Top targets:


Showing 1 to 20 of 118 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_75005523 4.572 ENSMUST00000001927.5
 Ltbp1
latent transforming growth factor beta binding protein 1
chr8_-_84773381 4.520 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr15_+_3270767 4.313 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr14_+_101840602 4.234 ENSMUST00000159314.1
 Lmo7
LIM domain only 7
chr2_-_33942111 3.726 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
 Gm13403


predicted gene 13403


chr14_+_101840501 3.090 ENSMUST00000159026.1
 Lmo7
LIM domain only 7
chr1_+_59482133 2.724 ENSMUST00000114246.2
ENSMUST00000037105.6
 Fzd7

frizzled homolog 7 (Drosophila)

chr13_-_97747399 2.691 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr13_-_97747373 2.574 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr10_-_17947997 2.149 ENSMUST00000037879.6
 Heca
headcase homolog (Drosophila)
chr18_-_62756275 2.109 ENSMUST00000067450.1
ENSMUST00000048109.5
 2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr1_+_165788681 2.098 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
 Cd247



CD247 antigen



chr5_-_122050102 2.038 ENSMUST00000154139.1
 Cux2
cut-like homeobox 2
chr7_+_99466004 1.818 ENSMUST00000037359.2
 Klhl35
kelch-like 35
chr1_+_165788746 1.771 ENSMUST00000161559.2
 Cd247
CD247 antigen
chrX_-_10117597 1.705 ENSMUST00000115543.2
ENSMUST00000044789.3
ENSMUST00000115544.2
 Srpx


sushi-repeat-containing protein


chr12_-_98577940 1.649 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr10_+_13966268 1.579 ENSMUST00000015645.4
 Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr14_+_54936456 1.520 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr17_-_79020816 1.424 ENSMUST00000168887.1
ENSMUST00000119284.1
 Prkd3

protein kinase D3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 4.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6 4.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 3.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 2.8 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.7 2.7 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 2.3 GO:0007614 short-term memory(GO:0007614)
0.0 2.0 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.6 1.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 1.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 1.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 1.1 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.2 0.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.8 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.2 0.7 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.7 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.3 GO:0005913 cell-cell adherens junction(GO:0005913)
1.5 4.6 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.0 3.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 1.5 GO:0030496 midbody(GO:0030496)
0.0 1.4 GO:0005871 kinesin complex(GO:0005871)
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.0 1.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.7 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.3 GO:0042805 actinin binding(GO:0042805)
1.1 4.6 GO:0050436 microfibril binding(GO:0050436)
0.0 4.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 4.3 GO:0008430 selenium binding(GO:0008430)
0.2 2.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 2.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.5 GO:0005125 cytokine activity(GO:0005125)
0.0 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 0.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.0 0.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)