Motif ID: Sox4
Z-value: 0.839
Transcription factors associated with Sox4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Sox4 | ENSMUSG00000076431.4 | Sox4 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox4 | mm10_v2_chr13_-_28953690_28953713 | 0.73 | 7.5e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.7 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.6 | 4.3 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.6 | 1.7 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.4 | 1.6 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.3 | 4.5 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.2 | 0.7 | GO:1904049 | regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 0.2 | 0.9 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.2 | 0.8 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.2 | 1.5 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.2 | 4.6 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.2 | 1.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 0.4 | GO:0048496 | maintenance of organ identity(GO:0048496) |
| 0.1 | 0.5 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.1 | 0.3 | GO:0071544 | diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.1 | 0.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 1.1 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.1 | 2.3 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 0.4 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.1 | 0.7 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.1 | 1.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 0.3 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.1 | 0.5 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.1 | 3.9 | GO:0050852 | T cell receptor signaling pathway(GO:0050852) |
| 0.0 | 0.7 | GO:0046697 | decidualization(GO:0046697) |
| 0.0 | 2.8 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.0 | 0.4 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
| 0.0 | 0.2 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.0 | 0.5 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.5 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.0 | 0.1 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.0 | 0.1 | GO:0046671 | negative regulation of retinal cell programmed cell death(GO:0046671) |
| 0.0 | 0.5 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.0 | 0.5 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.1 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.0 | 0.2 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.0 | 0.1 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.0 | 0.2 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 0.1 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.0 | 0.7 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
| 0.0 | 0.3 | GO:0007143 | female meiotic division(GO:0007143) |
| 0.0 | 1.1 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
| 0.0 | 2.0 | GO:0030705 | cytoskeleton-dependent intracellular transport(GO:0030705) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.6 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 1.0 | 3.9 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.3 | 1.2 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.1 | 0.4 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.1 | 0.7 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.1 | 0.5 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 7.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.4 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.5 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 1.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 1.7 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.8 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 1.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 1.1 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.7 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 1.5 | GO:0030496 | midbody(GO:0030496) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 4.6 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.3 | 4.3 | GO:0008430 | selenium binding(GO:0008430) |
| 0.2 | 7.3 | GO:0042805 | actinin binding(GO:0042805) |
| 0.2 | 2.8 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.2 | 0.7 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.1 | 1.6 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 2.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 1.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.4 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 0.5 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 0.5 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 0.5 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 0.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 1.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 0.3 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.3 | GO:0008486 | diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) |
| 0.1 | 0.5 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.7 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.0 | 1.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 1.4 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 1.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.7 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 1.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.3 | GO:0030235 | nitric-oxide synthase regulator activity(GO:0030235) |
| 0.0 | 1.5 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 4.5 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
