Motif ID: Hmga1

Z-value: 1.031


Transcription factors associated with Hmga1:

Gene SymbolEntrez IDGene Name
Hmga1 ENSMUSG00000046711.9 Hmga1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga1mm10_v2_chr17_+_27556613_275566350.612.0e-03Click!


Activity profile for motif Hmga1.

activity profile for motif Hmga1


Sorted Z-values histogram for motif Hmga1

Sorted Z-values for motif Hmga1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 24.108 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr15_-_56694525 5.866 ENSMUST00000050544.7
 Has2
hyaluronan synthase 2
chr16_-_26989974 4.674 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr1_+_107511416 4.058 ENSMUST00000009356.4
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr3_+_134236483 3.466 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr17_+_43953191 3.258 ENSMUST00000044792.4
 Rcan2
regulator of calcineurin 2
chr12_-_108003594 3.063 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr13_+_5861489 2.981 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6
chr3_+_102010138 2.943 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr10_+_88091070 2.914 ENSMUST00000048621.7
 Pmch
pro-melanin-concentrating hormone
chr9_-_100506844 2.844 ENSMUST00000112874.3
 Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr10_-_92165159 2.712 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
 Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr8_-_87959560 2.707 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr4_-_97584605 2.706 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_36056726 2.548 ENSMUST00000108124.3
 Lingo2
leucine rich repeat and Ig domain containing 2
chr19_-_24861828 2.514 ENSMUST00000047666.4
 Pgm5
phosphoglucomutase 5
chr17_+_85620816 2.444 ENSMUST00000175898.2
 Six3
sine oculis-related homeobox 3
chr10_-_33624587 2.438 ENSMUST00000160299.1
ENSMUST00000019920.6
 Clvs2

clavesin 2

chr17_+_43952999 2.183 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr1_-_158814469 2.035 ENSMUST00000161589.2
 Pappa2
pappalysin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 122 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 26.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 7.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.5 5.9 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 5.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 4.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 4.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
1.2 3.7 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.5 3.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 3.1 GO:0007052 mitotic spindle organization(GO:0007052)
1.0 2.9 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 2.9 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.7 2.8 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 2.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 2.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 2.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 2.0 GO:0006012 galactose metabolic process(GO:0006012)
0.1 2.0 GO:0060065 uterus development(GO:0060065)
0.0 2.0 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.3 1.9 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.5 3.2 GO:0031262 Ndc80 complex(GO:0031262)
0.2 2.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.2 GO:0043034 costamere(GO:0043034)
0.4 2.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 2.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.6 GO:0070852 cell body fiber(GO:0070852)
0.1 1.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.4 GO:0098803 respiratory chain complex(GO:0098803)
0.0 1.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.4 1.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 1.1 GO:0008290 F-actin capping protein complex(GO:0008290)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 19.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
2.0 5.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 5.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 4.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 3.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 3.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.5 2.8 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.5 2.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 2.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.1 2.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 2.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.7 2.0 GO:0004335 galactokinase activity(GO:0004335)
0.0 2.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 1.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.1 1.6 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)