Motif ID: Pou6f2_Pou4f2

Z-value: 0.834

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f2mm10_v2_chr13_-_18382041_18382041-0.491.8e-02Click!
Pou4f2mm10_v2_chr8_-_78436640_78436649-0.213.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_56296551 7.068 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr5_+_139543889 6.811 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr12_-_112511136 6.023 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr1_+_153665666 4.953 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr1_+_153665274 4.615 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr1_+_153665587 3.460 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 3.391 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr3_+_55782500 3.348 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr7_-_49636847 3.263 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr6_+_88724667 1.867 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr6_+_88724828 1.827 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr12_+_38781093 1.643 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr9_+_53771499 1.531 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr4_-_58499398 1.511 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr12_+_38780817 1.488 ENSMUST00000160856.1
Etv1
ets variant gene 1
chrX_+_114474312 1.487 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4

kelch-like 4

chr7_-_70366735 1.404 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr12_+_38780284 1.380 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_-_168767029 1.351 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr6_-_138426735 1.341 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chr2_-_168767136 1.319 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr10_-_92164666 1.290 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr14_-_69805524 1.182 ENSMUST00000022665.2
Rhobtb2
Rho-related BTB domain containing 2
chr19_+_24875679 1.181 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr4_-_133602168 1.154 ENSMUST00000057311.3
Sfn
stratifin
chr6_-_138422898 1.114 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr8_-_61902669 1.112 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr17_+_34592248 1.031 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr10_-_70655934 1.015 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr16_-_42340595 0.987 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr4_-_14621669 0.960 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr10_+_99263224 0.852 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr1_+_143777263 0.852 ENSMUST00000018333.6
Uchl5
ubiquitin carboxyl-terminal esterase L5
chrX_+_56447965 0.828 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chr4_+_5724304 0.760 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr9_+_15239045 0.727 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr14_+_27039001 0.647 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chrX_+_9885622 0.638 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chrX_-_59166080 0.604 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr9_-_60649793 0.574 ENSMUST00000053171.7
Lrrc49
leucine rich repeat containing 49
chr17_-_3557713 0.554 ENSMUST00000041003.6
Tfb1m
transcription factor B1, mitochondrial
chrX_+_153237748 0.549 ENSMUST00000112574.2
Klf8
Kruppel-like factor 8
chr17_+_85028347 0.537 ENSMUST00000024944.7
Slc3a1
solute carrier family 3, member 1
chr1_+_10993452 0.509 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr2_+_3114220 0.507 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr13_-_102906046 0.496 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr18_+_84851338 0.478 ENSMUST00000160180.1
Cyb5
cytochrome b-5
chr17_+_17402672 0.468 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr10_-_128549102 0.465 ENSMUST00000176906.1
Rpl41
ribosomal protein L41
chr10_-_128549125 0.462 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
Rpl41


ribosomal protein L41


chr4_+_150237694 0.459 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr4_+_150853919 0.451 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr12_-_56535047 0.446 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr13_-_102905740 0.441 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr8_+_25720054 0.436 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr13_+_99100698 0.429 ENSMUST00000181742.1
Gm807
predicted gene 807
chr4_+_150237211 0.429 ENSMUST00000133839.1
Eno1
enolase 1, alpha non-neuron
chr5_-_103211251 0.404 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr16_-_59632520 0.404 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr10_-_95673451 0.370 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr2_-_33718789 0.369 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr7_+_28881656 0.342 ENSMUST00000066880.4
Capn12
calpain 12
chr18_-_88927447 0.336 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr4_+_115088708 0.328 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chr6_+_77242715 0.300 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_77242644 0.298 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chrX_-_53269786 0.295 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr10_+_127420867 0.273 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr4_-_110287479 0.270 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr3_-_88552859 0.262 ENSMUST00000119002.1
ENSMUST00000029698.8
Lamtor2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr3_-_154328634 0.257 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr8_+_107031218 0.249 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr4_-_14621494 0.247 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr6_+_63255971 0.236 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr1_-_172027269 0.233 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr2_-_106002008 0.221 ENSMUST00000155811.1
Dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr16_-_45724600 0.218 ENSMUST00000096057.4
Tagln3
transgelin 3
chrX_+_153237466 0.218 ENSMUST00000143880.1
Klf8
Kruppel-like factor 8
chr12_+_69963452 0.207 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr19_-_19001099 0.186 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr8_-_83458386 0.175 ENSMUST00000081506.3
Scoc
short coiled-coil protein
chr18_-_15063560 0.170 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr12_-_24493656 0.170 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr3_-_130730375 0.166 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr12_-_81532840 0.164 ENSMUST00000166664.1
ENSMUST00000164386.1
ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
Gm20498

Synj2bp


predicted gene 20498

synaptojanin 2 binding protein


chr4_+_117849361 0.159 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr7_-_28338719 0.148 ENSMUST00000003527.8
Supt5
suppressor of Ty 5
chr5_-_120777628 0.147 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr4_+_102589687 0.146 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr19_+_41933464 0.123 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr17_+_46681038 0.108 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr5_+_29195983 0.106 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr2_-_148046896 0.099 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr11_-_89538556 0.096 ENSMUST00000169201.1
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr7_+_5080214 0.095 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr3_-_130730310 0.092 ENSMUST00000062601.7
Rpl34
ribosomal protein L34
chr8_-_92355764 0.090 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr7_+_144175513 0.086 ENSMUST00000105900.1
Shank2
SH3/ankyrin domain gene 2
chr4_-_14621805 0.081 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr8_-_84662841 0.076 ENSMUST00000060427.4
Ier2
immediate early response 2
chr11_+_60537978 0.071 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr3_+_68572245 0.068 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr9_+_32116040 0.063 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr13_-_38635036 0.057 ENSMUST00000035899.6
Bloc1s5
biogenesis of organelles complex-1, subunit 5, muted
chr6_+_29859374 0.057 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chrM_+_7005 0.049 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr12_+_52699297 0.047 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr2_-_92392634 0.047 ENSMUST00000111279.2
Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chr2_-_32431104 0.037 ENSMUST00000127961.1
ENSMUST00000136361.1
ENSMUST00000052119.7
Slc25a25


solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25


chr2_-_67433181 0.033 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr8_-_54724317 0.026 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr10_+_127421124 0.023 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr2_+_132847719 0.022 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chrX_-_51018011 0.015 ENSMUST00000053593.7
Rap2c
RAP2C, member of RAS oncogene family
chr3_-_88456397 0.009 ENSMUST00000141471.1
ENSMUST00000123753.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr7_-_116031047 0.007 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr9_+_113812547 0.006 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
1.3 16.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.9 6.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.5 3.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 0.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.3 1.4 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 1.3 GO:0019532 oxalate transport(GO:0019532)
0.2 3.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.5 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.1 2.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 4.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.2 GO:0031424 keratinization(GO:0031424) establishment of skin barrier(GO:0061436)
0.1 1.0 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.6 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:0046909 intermembrane transport(GO:0046909)
0.1 0.9 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 2.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) prepulse inhibition(GO:0060134)
0.0 0.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.6 GO:0000154 rRNA modification(GO:0000154)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.5 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 16.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 3.7 GO:0043196 varicosity(GO:0043196)
0.1 0.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.6 GO:0070382 exocytic vesicle(GO:0070382)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.7 GO:0000792 heterochromatin(GO:0000792)
0.0 0.0 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.4 17.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 3.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 7.1 GO:0008009 chemokine activity(GO:0008009)
0.2 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 14.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 1.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)