Motif ID: Pou6f2_Pou4f2

Z-value: 0.834

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f2mm10_v2_chr13_-_18382041_18382041-0.491.8e-02Click!
Pou4f2mm10_v2_chr8_-_78436640_78436649-0.213.3e-01Click!


Activity profile for motif Pou6f2_Pou4f2.

activity profile for motif Pou6f2_Pou4f2


Sorted Z-values histogram for motif Pou6f2_Pou4f2

Sorted Z-values for motif Pou6f2_Pou4f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 117 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_56296551 7.068 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr5_+_139543889 6.811 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr12_-_112511136 6.023 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr1_+_153665666 4.953 ENSMUST00000111814.1
ENSMUST00000111810.1
 Rgs8

regulator of G-protein signaling 8

chr1_+_153665274 4.615 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr1_+_153665587 3.460 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 3.391 ENSMUST00000147482.1
 Rgs8
regulator of G-protein signaling 8
chr3_+_55782500 3.348 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr7_-_49636847 3.263 ENSMUST00000032717.6
 Dbx1
developing brain homeobox 1
chr6_+_88724667 1.867 ENSMUST00000163271.1
 Mgll
monoglyceride lipase
chr6_+_88724828 1.827 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr12_+_38781093 1.643 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr9_+_53771499 1.531 ENSMUST00000048670.8
 Slc35f2
solute carrier family 35, member F2
chr4_-_58499398 1.511 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr12_+_38780817 1.488 ENSMUST00000160856.1
 Etv1
ets variant gene 1
chrX_+_114474312 1.487 ENSMUST00000113371.1
ENSMUST00000040504.5
 Klhl4

kelch-like 4

chr7_-_70366735 1.404 ENSMUST00000089565.5
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr12_+_38780284 1.380 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr2_-_168767029 1.351 ENSMUST00000075044.3
 Sall4
sal-like 4 (Drosophila)
chr6_-_138426735 1.341 ENSMUST00000162932.1
 Lmo3
LIM domain only 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 16.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
2.4 7.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.9 6.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 4.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.5 3.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 3.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 2.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 2.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.4 1.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.4 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 1.3 GO:0019532 oxalate transport(GO:0019532)
0.1 1.2 GO:0031424 keratinization(GO:0031424) establishment of skin barrier(GO:0061436)
0.1 1.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.0 GO:0016198 axon choice point recognition(GO:0016198)
0.3 0.9 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.9 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.6 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.6 GO:0000154 rRNA modification(GO:0000154)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 16.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 3.7 GO:0043196 varicosity(GO:0043196)
0.0 2.7 GO:0000792 heterochromatin(GO:0000792)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.1 GO:0002102 podosome(GO:0002102)
0.0 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.9 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:0044302 dentate gyrus mossy fiber(GO:0044302)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 17.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 14.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 7.1 GO:0008009 chemokine activity(GO:0008009)
0.3 3.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.5 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)