Motif ID: Foxn1

Z-value: 0.466


Transcription factors associated with Foxn1:

Gene SymbolEntrez IDGene Name
Foxn1 ENSMUSG00000002057.4 Foxn1



Activity profile for motif Foxn1.

activity profile for motif Foxn1


Sorted Z-values histogram for motif Foxn1

Sorted Z-values for motif Foxn1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxn1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_86963279 0.668 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr6_+_38433913 0.647 ENSMUST00000160583.1
Ubn2
ubinuclein 2
chrX_-_111463103 0.621 ENSMUST00000137712.2
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chrX_+_151803642 0.549 ENSMUST00000156616.2
Huwe1
HECT, UBA and WWE domain containing 1
chr9_+_70207342 0.543 ENSMUST00000034745.7
Myo1e
myosin IE
chr9_-_119578981 0.476 ENSMUST00000117911.1
ENSMUST00000120420.1
Scn5a

sodium channel, voltage-gated, type V, alpha

chrX_-_111463149 0.472 ENSMUST00000096348.3
ENSMUST00000113428.2
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr11_+_30771726 0.466 ENSMUST00000041231.7
Psme4
proteasome (prosome, macropain) activator subunit 4
chr13_+_77135513 0.392 ENSMUST00000168779.1
2210408I21Rik
RIKEN cDNA 2210408I21 gene
chrX_-_111463043 0.387 ENSMUST00000065976.5
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr17_+_6106464 0.385 ENSMUST00000142030.1
Tulp4
tubby like protein 4
chr3_-_116007399 0.366 ENSMUST00000067485.3
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr8_-_111876661 0.361 ENSMUST00000034431.1
Tmem170
transmembrane protein 170
chr3_-_158562199 0.346 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr14_+_75284343 0.341 ENSMUST00000022577.5
Zc3h13
zinc finger CCCH type containing 13
chr11_-_104550392 0.323 ENSMUST00000106962.2
Cdc27
cell division cycle 27
chr8_-_83332416 0.320 ENSMUST00000177594.1
ENSMUST00000053902.3
Elmod2

ELMO/CED-12 domain containing 2

chr9_-_95750335 0.318 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr6_+_149408973 0.312 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr11_+_93996082 0.297 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr16_-_96082389 0.289 ENSMUST00000099502.2
ENSMUST00000023631.8
ENSMUST00000113829.1
ENSMUST00000153398.1
Brwd1



bromodomain and WD repeat domain containing 1



chr6_-_134792596 0.282 ENSMUST00000100857.3
Dusp16
dual specificity phosphatase 16
chr6_-_32588192 0.267 ENSMUST00000115096.2
Plxna4
plexin A4
chr2_+_110017879 0.260 ENSMUST00000150183.2
Ccdc34
coiled-coil domain containing 34
chr18_-_46525940 0.260 ENSMUST00000036226.5
Fem1c
fem-1 homolog c (C.elegans)
chr9_-_72985344 0.258 ENSMUST00000124565.2
Gm5918
predicted gene 5918
chr13_-_77135416 0.252 ENSMUST00000159462.1
ENSMUST00000151524.2
Ankrd32

ankyrin repeat domain 32

chr1_-_161876656 0.247 ENSMUST00000048377.5
Suco
SUN domain containing ossification factor
chrX_-_74085656 0.243 ENSMUST00000033770.6
Mecp2
methyl CpG binding protein 2
chr19_+_36834215 0.237 ENSMUST00000025729.5
Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr11_-_104550460 0.236 ENSMUST00000106961.1
ENSMUST00000093923.2
Cdc27

cell division cycle 27

chr14_+_63606491 0.224 ENSMUST00000119973.2
Xkr6
X Kell blood group precursor related family member 6 homolog
chr2_+_110017806 0.222 ENSMUST00000028580.5
Ccdc34
coiled-coil domain containing 34
chr7_-_81829431 0.218 ENSMUST00000026093.7
Btbd1
BTB (POZ) domain containing 1
chr4_-_121215071 0.218 ENSMUST00000056635.5
Rlf
rearranged L-myc fusion sequence
chr8_+_60993189 0.216 ENSMUST00000034065.7
ENSMUST00000120689.1
Nek1

NIMA (never in mitosis gene a)-related expressed kinase 1

chr2_-_125858985 0.208 ENSMUST00000110462.1
Cops2
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
chr9_+_72985504 0.205 ENSMUST00000156879.1
Ccpg1
cell cycle progression 1
chrX_-_23285532 0.202 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr12_+_86082555 0.194 ENSMUST00000054565.6
Ift43
intraflagellar transport 43 homolog (Chlamydomonas)
chrX_-_74085586 0.193 ENSMUST00000123362.1
ENSMUST00000140399.1
ENSMUST00000100750.3
Mecp2


methyl CpG binding protein 2


chr8_-_11008458 0.191 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr18_-_10610048 0.184 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr1_+_178405881 0.181 ENSMUST00000027775.7
Efcab2
EF-hand calcium binding domain 2
chr4_+_116558056 0.175 ENSMUST00000106475.1
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr1_+_127868773 0.175 ENSMUST00000037649.5
Rab3gap1
RAB3 GTPase activating protein subunit 1
chr14_+_111675113 0.170 ENSMUST00000042767.7
Slitrk5
SLIT and NTRK-like family, member 5
chr14_-_99099701 0.169 ENSMUST00000042471.9
Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr11_-_69758223 0.167 ENSMUST00000071213.3
Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr7_+_100372224 0.166 ENSMUST00000051777.8
ENSMUST00000098259.4
C2cd3

C2 calcium-dependent domain containing 3

chr19_+_46152505 0.166 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr11_+_88068242 0.166 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr4_+_116557658 0.164 ENSMUST00000030460.8
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr2_-_125859139 0.162 ENSMUST00000110463.1
ENSMUST00000028635.5
Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr9_+_72985410 0.160 ENSMUST00000037977.8
Ccpg1
cell cycle progression 1
chrX_+_151803313 0.154 ENSMUST00000026292.8
Huwe1
HECT, UBA and WWE domain containing 1
chr9_+_72985568 0.149 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
Ccpg1


cell cycle progression 1


chr12_-_105685235 0.144 ENSMUST00000041055.7
Atg2b
autophagy related 2B
chr13_-_64274879 0.140 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr1_-_178337774 0.131 ENSMUST00000037748.7
Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr5_+_130171798 0.124 ENSMUST00000119797.1
ENSMUST00000148264.1
Rabgef1

RAB guanine nucleotide exchange factor (GEF) 1

chr6_-_39725448 0.121 ENSMUST00000002487.8
Braf
Braf transforming gene
chrX_+_99136119 0.114 ENSMUST00000052839.6
Efnb1
ephrin B1
chr1_+_95313607 0.114 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr13_-_64274962 0.113 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr18_-_37935378 0.110 ENSMUST00000025337.7
Diap1
diaphanous homolog 1 (Drosophila)
chr7_+_126847908 0.104 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr4_+_40722461 0.103 ENSMUST00000030118.3
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr11_-_116131073 0.100 ENSMUST00000106440.2
ENSMUST00000067632.3
Trim65

tripartite motif-containing 65

chr4_+_40722912 0.097 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr7_-_133776681 0.078 ENSMUST00000130182.1
ENSMUST00000106139.1
Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chr2_-_127788854 0.077 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr17_-_80062333 0.077 ENSMUST00000061331.7
Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr11_-_50210765 0.075 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
Sqstm1


sequestosome 1


chr2_+_125859134 0.075 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chrX_-_74249819 0.075 ENSMUST00000114299.1
Flna
filamin, alpha
chr14_-_57746044 0.075 ENSMUST00000173990.1
ENSMUST00000022531.7
Lats2

large tumor suppressor 2

chr2_+_181497223 0.070 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr19_-_36919606 0.069 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr6_-_30896735 0.068 ENSMUST00000048774.6
ENSMUST00000166192.1
ENSMUST00000135230.1
Copg2


coatomer protein complex, subunit gamma 2


chr9_-_75683992 0.068 ENSMUST00000034699.6
Scg3
secretogranin III
chr9_+_69989466 0.068 ENSMUST00000034754.5
ENSMUST00000085393.6
ENSMUST00000117450.1
Bnip2


BCL2/adenovirus E1B interacting protein 2


chr9_-_106199253 0.066 ENSMUST00000140761.1
Ppm1m
protein phosphatase 1M
chr12_+_105685352 0.065 ENSMUST00000051934.5
Gskip
GSK3B interacting protein
chr7_-_133776772 0.060 ENSMUST00000033290.5
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr11_-_69758630 0.054 ENSMUST00000058470.9
Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr8_+_105636509 0.052 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr2_+_181497165 0.047 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr4_+_122836236 0.046 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
Ppt1


palmitoyl-protein thioesterase 1


chr2_-_44927206 0.041 ENSMUST00000100127.2
Gtdc1
glycosyltransferase-like domain containing 1
chr15_-_101054399 0.040 ENSMUST00000178140.1
Fignl2
fidgetin-like 2
chr10_+_88379127 0.040 ENSMUST00000127615.1
Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr10_+_19934472 0.039 ENSMUST00000095806.3
ENSMUST00000120259.1
Map3k5

mitogen-activated protein kinase kinase kinase 5

chr9_-_45984816 0.023 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr19_+_43612299 0.018 ENSMUST00000057178.9
Nkx2-3
NK2 homeobox 3
chr2_+_131210501 0.017 ENSMUST00000110206.1
Ap5s1
adaptor-related protein 5 complex, sigma 1 subunit
chr11_-_120348475 0.010 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr6_+_28480337 0.006 ENSMUST00000001460.7
ENSMUST00000167201.1
Snd1

staphylococcal nuclease and tudor domain containing 1

chr3_+_103020546 0.005 ENSMUST00000029446.8
Csde1
cold shock domain containing E1, RNA binding
chr3_+_116007457 0.005 ENSMUST00000029575.5
ENSMUST00000106501.1
Extl2

exostoses (multiple)-like 2

chrX_+_101429555 0.005 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chr5_-_115300957 0.002 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr7_+_133776857 0.002 ENSMUST00000065359.5
ENSMUST00000151031.1
ENSMUST00000121560.1
Fank1


fibronectin type 3 and ankyrin repeat domains 1


chr10_+_88379217 0.001 ENSMUST00000130301.1
ENSMUST00000020251.8
Gnptab

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

chr9_-_64737623 0.001 ENSMUST00000169058.1
Rab11a
RAB11a, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0086017 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) Purkinje myocyte action potential(GO:0086017) membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.4 GO:0009405 pathogenesis(GO:0009405)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.3 GO:1900275 negative regulation of phospholipase C activity(GO:1900275) regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 0.3 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:1903061 glutamate secretion, neurotransmission(GO:0061535) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.1 0.2 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.4 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 0.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0006284 base-excision repair(GO:0006284)
0.0 0.0 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.2 GO:0021756 striatum development(GO:0021756)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)