Motif ID: Erg

Z-value: 1.217


Transcription factors associated with Erg:

Gene SymbolEntrez IDGene Name
Erg ENSMUSG00000040732.12 Erg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ergmm10_v2_chr16_-_95459245_954593840.602.3e-03Click!


Activity profile for motif Erg.

activity profile for motif Erg


Sorted Z-values histogram for motif Erg

Sorted Z-values for motif Erg



Network of associatons between targets according to the STRING database.



First level regulatory network of Erg

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 8.327 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893077 6.466 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893127 5.462 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr7_-_27181149 5.111 ENSMUST00000071986.6
ENSMUST00000121848.1
 Mia

melanoma inhibitory activity

chr13_-_41487306 5.037 ENSMUST00000021794.6
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr16_+_43363855 4.989 ENSMUST00000156367.1
 Zbtb20
zinc finger and BTB domain containing 20
chr1_-_56969864 4.325 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_56972437 4.202 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr16_+_43364145 4.172 ENSMUST00000148775.1
 Zbtb20
zinc finger and BTB domain containing 20
chr12_+_75308308 3.675 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr1_-_56969827 3.628 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr9_+_70207342 3.530 ENSMUST00000034745.7
 Myo1e
myosin IE
chr5_+_111733924 3.334 ENSMUST00000180627.1
 Gm26897
predicted gene, 26897
chr12_-_34528844 3.072 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9
chr2_+_32646586 2.946 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr18_+_5593566 2.910 ENSMUST00000160910.1
 Zeb1
zinc finger E-box binding homeobox 1
chr11_-_55419898 2.826 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr1_+_16688405 2.773 ENSMUST00000026881.4
 Ly96
lymphocyte antigen 96
chr1_+_165788681 2.669 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
 Cd247



CD247 antigen



chr16_+_17797282 2.591 ENSMUST00000012161.3
 Scarf2
scavenger receptor class F, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 213 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 20.3 GO:0042572 retinol metabolic process(GO:0042572)
0.8 12.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 9.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 4.5 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.4 3.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 3.6 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)
0.7 3.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.2 3.0 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 3.0 GO:0045026 plasma membrane fusion(GO:0045026)
1.0 2.9 GO:0003032 detection of oxygen(GO:0003032)
0.3 2.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 2.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.6 2.8 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 2.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.8 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 2.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 2.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.5 2.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.7 2.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.5 2.2 GO:0050904 diapedesis(GO:0050904)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 19.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 5.5 GO:0000922 spindle pole(GO:0000922)
1.2 4.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 4.8 GO:0043235 receptor complex(GO:0043235)
0.1 3.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 3.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.3 3.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.7 2.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.5 2.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.7 2.2 GO:0097443 sorting endosome(GO:0097443)
0.4 2.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 2.0 GO:0030139 endocytic vesicle(GO:0030139)
0.2 2.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.9 GO:0001739 sex chromatin(GO:0001739)
0.1 1.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 1.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 20.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 16.5 GO:0003682 chromatin binding(GO:0003682)
0.1 10.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 5.3 GO:0005516 calmodulin binding(GO:0005516)
0.2 4.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 4.6 GO:0005518 collagen binding(GO:0005518)
0.0 4.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.9 GO:0017124 SH3 domain binding(GO:0017124)
0.2 3.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.7 3.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 3.5 GO:0008083 growth factor activity(GO:0008083)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.3 3.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 3.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 3.0 GO:0017154 semaphorin receptor activity(GO:0017154)
1.0 2.9 GO:0005534 galactose binding(GO:0005534)
0.2 2.9 GO:0017166 vinculin binding(GO:0017166)
0.9 2.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 2.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 2.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)