Motif ID: Foxl1

Z-value: 0.490


Transcription factors associated with Foxl1:

Gene SymbolEntrez IDGene Name
Foxl1 ENSMUSG00000097084.1 Foxl1
Foxl1 ENSMUSG00000043867.5 Foxl1



Activity profile for motif Foxl1.

activity profile for motif Foxl1


Sorted Z-values histogram for motif Foxl1

Sorted Z-values for motif Foxl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_122289297 1.185 ENSMUST00000064989.5
ENSMUST00000064921.4
 Prkcb

protein kinase C, beta

chr10_+_26229707 1.034 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr17_-_91092715 0.979 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr6_-_23248264 0.935 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr13_-_23622502 0.756 ENSMUST00000062045.2
 Hist1h1e
histone cluster 1, H1e
chr4_+_11191726 0.755 ENSMUST00000029866.9
ENSMUST00000108324.3
 Ccne2

cyclin E2

chr18_-_25753852 0.710 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr6_-_147264124 0.651 ENSMUST00000052296.6
 Pthlh
parathyroid hormone-like peptide
chr15_+_43477213 0.641 ENSMUST00000022962.6
 Emc2
ER membrane protein complex subunit 2
chrX_+_112604274 0.604 ENSMUST00000071814.6
 Zfp711
zinc finger protein 711
chr10_-_102490418 0.580 ENSMUST00000020040.3
 Nts
neurotensin
chr13_+_23763660 0.552 ENSMUST00000055770.1
 Hist1h1a
histone cluster 1, H1a
chr9_+_71215779 0.520 ENSMUST00000034723.5
 Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr2_+_119325784 0.507 ENSMUST00000102517.3
 Dll4
delta-like 4 (Drosophila)
chr11_+_31872100 0.494 ENSMUST00000020543.6
ENSMUST00000109412.2
 Cpeb4

cytoplasmic polyadenylation element binding protein 4

chrM_+_2743 0.436 ENSMUST00000082392.1
 mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr9_-_101198999 0.411 ENSMUST00000066773.7
 Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr16_+_45093611 0.382 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chr17_+_40811089 0.323 ENSMUST00000024721.7
 Rhag
Rhesus blood group-associated A glycoprotein
chr13_+_23575753 0.322 ENSMUST00000105105.1
 Hist1h3d
histone cluster 1, H3d
chr1_-_170110491 0.304 ENSMUST00000027985.2
 Ddr2
discoidin domain receptor family, member 2
chr12_+_69963452 0.295 ENSMUST00000110560.1
 Gm3086
predicted gene 3086
chr16_+_30065333 0.290 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr18_+_34409415 0.284 ENSMUST00000166156.1
ENSMUST00000014647.7
 Pkd2l2

polycystic kidney disease 2-like 2

chrX_+_18162575 0.240 ENSMUST00000044484.6
ENSMUST00000052368.8
 Kdm6a

lysine (K)-specific demethylase 6A

chr9_+_44069421 0.229 ENSMUST00000114830.2
 Usp2
ubiquitin specific peptidase 2
chr2_+_18055203 0.228 ENSMUST00000028076.8
 Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr2_-_147186389 0.190 ENSMUST00000109970.3
ENSMUST00000067075.5
 Nkx2-2

NK2 homeobox 2

chr2_-_94264713 0.183 ENSMUST00000129661.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene
chr13_+_23555023 0.158 ENSMUST00000045301.6
 Hist1h1d
histone cluster 1, H1d
chr2_+_65620829 0.144 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr2_-_94264745 0.140 ENSMUST00000134563.1
 E530001K10Rik
RIKEN cDNA E530001K10 gene
chr10_+_56377300 0.108 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr6_+_42286676 0.090 ENSMUST00000031894.6
 Clcn1
chloride channel 1
chr4_-_134853294 0.070 ENSMUST00000030628.8
 Tmem57
transmembrane protein 57
chr2_+_91255954 0.064 ENSMUST00000134699.1
 Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chrX_-_94123087 0.063 ENSMUST00000113925.1
 Zfx
zinc finger protein X-linked
chr15_-_11905609 0.061 ENSMUST00000066529.3
 Npr3
natriuretic peptide receptor 3
chr6_-_134887783 0.053 ENSMUST00000066107.6
 Gpr19
G protein-coupled receptor 19
chr18_-_15151427 0.032 ENSMUST00000025992.6
 Kctd1
potassium channel tetramerisation domain containing 1
chr6_+_42286709 0.002 ENSMUST00000163936.1
 Clcn1
chloride channel 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.2 1.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 1.0 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 0.5 GO:0035799 ureter maturation(GO:0035799)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.7 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:0021557 oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.5 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)