Motif ID: Tgif1_Meis3

Z-value: 1.262

Transcription factors associated with Tgif1_Meis3:

Gene SymbolEntrez IDGene Name
Meis3 ENSMUSG00000041420.12 Meis3
Tgif1 ENSMUSG00000047407.11 Tgif1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis3mm10_v2_chr7_+_16175275_16175438-0.736.8e-05Click!
Tgif1mm10_v2_chr17_-_70853482_70853546-0.711.5e-04Click!


Activity profile for motif Tgif1_Meis3.

activity profile for motif Tgif1_Meis3


Sorted Z-values histogram for motif Tgif1_Meis3

Sorted Z-values for motif Tgif1_Meis3



Network of associatons between targets according to the STRING database.



First level regulatory network of Tgif1_Meis3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_49246131 7.266 ENSMUST00000064395.6
 Nav2
neuron navigator 2
chr15_-_58076456 5.555 ENSMUST00000070143.6
ENSMUST00000110168.1
 Zhx1

zinc fingers and homeoboxes 1

chr4_-_82705735 5.153 ENSMUST00000155821.1
 Nfib
nuclear factor I/B
chr15_+_18818895 4.636 ENSMUST00000166873.2
 Cdh10
cadherin 10
chr8_-_84800024 4.367 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr17_+_83215271 4.297 ENSMUST00000170794.1
 Pkdcc
protein kinase domain containing, cytoplasmic
chr4_-_64046925 4.154 ENSMUST00000107377.3
 Tnc
tenascin C
chr13_-_97747399 3.913 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_+_49246812 3.696 ENSMUST00000184945.1
 Nav2
neuron navigator 2
chr7_-_97417730 3.670 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr2_-_77519565 3.645 ENSMUST00000111830.2
 Zfp385b
zinc finger protein 385B
chr3_-_58885212 3.547 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
 Clrn1


clarin 1


chr13_-_97747373 3.409 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_-_116968827 3.357 ENSMUST00000119557.1
 Palmd
palmdelphin
chr3_-_116968969 3.104 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr7_+_112225856 3.032 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
 Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr2_-_113758638 2.881 ENSMUST00000099575.3
 Grem1
gremlin 1
chr15_-_58076183 2.791 ENSMUST00000177276.1
ENSMUST00000175805.2
ENSMUST00000177504.2
ENSMUST00000176076.1
ENSMUST00000177176.1
 Zhx1

9130401M01Rik


zinc fingers and homeoboxes 1

RIKEN cDNA 9130401M01 gene


chr15_-_8710734 2.595 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_67974567 2.594 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
 Psd3


pleckstrin and Sec7 domain containing 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 525 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 11.0 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
1.3 5.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 4.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.1 4.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.9 4.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
1.0 4.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 4.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
1.3 4.0 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.2 3.6 GO:0097090 presynaptic membrane organization(GO:0097090)
0.2 3.6 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.3 3.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 3.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.3 3.0 GO:0050957 equilibrioception(GO:0050957)
1.0 2.9 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.6 2.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.6 2.9 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.4 2.9 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 2.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.2 2.8 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.2 2.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 180 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 15.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 6.9 GO:0005802 trans-Golgi network(GO:0005802)
0.4 5.2 GO:0043205 fibril(GO:0043205)
0.2 4.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 4.5 GO:0090544 BAF-type complex(GO:0090544)
0.1 4.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
1.3 4.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 3.7 GO:0030175 filopodium(GO:0030175)
0.1 3.6 GO:0033268 node of Ranvier(GO:0033268)
0.3 2.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.7 2.8 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 2.8 GO:0031526 brush border membrane(GO:0031526)
0.7 2.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 2.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.6 GO:0043197 dendritic spine(GO:0043197)
0.8 2.4 GO:0071953 elastic fiber(GO:0071953)
0.0 2.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 2.2 GO:0097449 astrocyte projection(GO:0097449)
0.1 2.2 GO:0008023 transcription elongation factor complex(GO:0008023)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 333 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.0 GO:0008201 heparin binding(GO:0008201)
0.1 12.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 8.4 GO:0017137 Rab GTPase binding(GO:0017137)
1.1 5.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 5.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 5.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.5 5.0 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 4.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 4.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
1.0 4.0 GO:0050436 microfibril binding(GO:0050436)
0.7 3.9 GO:0045545 syndecan binding(GO:0045545)
0.2 3.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.6 GO:0032452 histone demethylase activity(GO:0032452)
0.1 3.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.8 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 2.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.7 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.2 2.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)