Motif ID: Meis1

Z-value: 0.641


Transcription factors associated with Meis1:

Gene SymbolEntrez IDGene Name
Meis1 ENSMUSG00000020160.12 Meis1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis1mm10_v2_chr11_-_19018956_190189730.908.0e-09Click!


Activity profile for motif Meis1.

activity profile for motif Meis1


Sorted Z-values histogram for motif Meis1

Sorted Z-values for motif Meis1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 7.376 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr9_+_87022014 2.474 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
 Cyb5r4


cytochrome b5 reductase 4


chr14_-_98169542 2.446 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr3_+_125404292 2.275 ENSMUST00000144344.1
 Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_109123104 2.250 ENSMUST00000029477.6
 Slc25a24
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chr14_-_47411666 2.208 ENSMUST00000111778.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr6_+_4747306 2.207 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
 Peg10


paternally expressed 10


chr11_+_44617310 2.184 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr1_-_138842429 2.045 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr11_-_64436653 2.024 ENSMUST00000177999.1
 F930015N05Rik
RIKEN cDNA F930015N05 gene
chr8_+_108714644 1.642 ENSMUST00000043896.8
 Zfhx3
zinc finger homeobox 3
chr3_+_134828993 1.449 ENSMUST00000029822.4
 Tacr3
tachykinin receptor 3
chrX_-_23365044 1.203 ENSMUST00000115313.1
 Klhl13
kelch-like 13
chr8_+_127064107 1.151 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
 Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr8_+_127064022 1.118 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
 Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr2_-_112480817 1.116 ENSMUST00000099589.2
 Chrm5
cholinergic receptor, muscarinic 5
chr9_-_100546053 1.094 ENSMUST00000116522.1
 Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr13_+_108316395 1.063 ENSMUST00000171178.1
 Depdc1b
DEP domain containing 1B
chr1_+_169969409 1.062 ENSMUST00000180638.1
 3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr7_+_90426312 1.044 ENSMUST00000061391.7
 Ccdc89
coiled-coil domain containing 89

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 94 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 7.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 2.5 GO:0046677 response to antibiotic(GO:0046677)
0.8 2.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 2.3 GO:0003383 apical constriction(GO:0003383)
0.4 2.2 GO:0015867 ATP transport(GO:0015867)
0.0 2.1 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.4 2.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.5 1.6 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.5 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.3 1.2 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 1.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.2 GO:0010950 positive regulation of endopeptidase activity(GO:0010950)
0.2 1.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 0.9 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.9 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 0.9 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.8 GO:0060065 uterus development(GO:0060065)
0.0 0.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.3 GO:0033269 internode region of axon(GO:0033269)
0.1 2.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.6 GO:0000792 heterochromatin(GO:0000792)
0.3 1.3 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.3 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.0 0.5 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.3 2.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.8 2.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 2.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.6 2.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.2 2.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 1.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.3 0.8 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)