Motif ID: Hivep1

Z-value: 0.978


Transcription factors associated with Hivep1:

Gene SymbolEntrez IDGene Name
Hivep1 ENSMUSG00000021366.7 Hivep1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hivep1mm10_v2_chr13_+_42052015_420520720.193.8e-01Click!


Activity profile for motif Hivep1.

activity profile for motif Hivep1


Sorted Z-values histogram for motif Hivep1

Sorted Z-values for motif Hivep1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hivep1

PNG image of the network

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Top targets:


Showing 1 to 20 of 158 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_88000350 6.667 ENSMUST00000090971.5
Bcan
brevican
chr10_-_27616895 5.916 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr14_+_80000292 4.270 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr5_-_134747241 4.115 ENSMUST00000015138.9
Eln
elastin
chr3_-_107760221 4.026 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr2_-_113758638 3.738 ENSMUST00000099575.3
Grem1
gremlin 1
chr1_-_156204998 2.353 ENSMUST00000015628.3
Fam163a
family with sequence similarity 163, member A
chr3_-_53657339 2.309 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr11_-_100411874 2.277 ENSMUST00000141840.1
Leprel4
leprecan-like 4
chr17_-_34000257 2.138 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr4_-_40239779 1.977 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_97487801 1.864 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr4_-_82505749 1.824 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr7_-_101302020 1.811 ENSMUST00000122116.1
ENSMUST00000120267.1
Atg16l2

autophagy related 16-like 2 (S. cerevisiae)

chr2_-_104257400 1.606 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr18_+_37496997 1.594 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr2_+_130405256 1.564 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr6_+_55336424 1.519 ENSMUST00000004774.3
Aqp1
aquaporin 1
chr17_+_35439155 1.519 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr2_-_5063996 1.458 ENSMUST00000114996.1
Optn
optineurin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 7.8 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 6.7 GO:0021766 hippocampus development(GO:0021766)
1.2 5.9 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 4.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 4.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 3.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.8 3.1 GO:0009597 detection of virus(GO:0009597)
0.0 3.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.7 2.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.3 2.3 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 2.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.5 1.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.8 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 1.6 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 1.6 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 1.6 GO:0098792 xenophagy(GO:0098792)
0.8 1.5 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 1.4 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 1.4 GO:1901998 toxin transport(GO:1901998)
0.4 1.3 GO:0048352 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 4.3 GO:0042581 specific granule(GO:0042581)
1.4 4.1 GO:0071953 elastic fiber(GO:0071953)
0.2 4.1 GO:0005605 basal lamina(GO:0005605)
1.3 4.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 3.6 GO:0001726 ruffle(GO:0001726)
0.0 3.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.3 GO:0031143 pseudopodium(GO:0031143)
0.1 1.8 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.4 1.5 GO:0032127 dense core granule membrane(GO:0032127)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 1.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.4 GO:0034399 nuclear periphery(GO:0034399)
0.4 1.3 GO:0000802 transverse filament(GO:0000802)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.3 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 5.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 4.3 GO:0045296 cadherin binding(GO:0045296)
0.0 4.3 GO:0005125 cytokine activity(GO:0005125)
0.1 4.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 3.7 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 3.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 2.8 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.8 2.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 1.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 1.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.4 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.3 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.3 1.2 GO:0004096 catalase activity(GO:0004096)