Motif ID: Ep300

Z-value: 0.620


Transcription factors associated with Ep300:

Gene SymbolEntrez IDGene Name
Ep300 ENSMUSG00000055024.6 Ep300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ep300mm10_v2_chr15_+_81586206_81586250-0.453.3e-02Click!


Activity profile for motif Ep300.

activity profile for motif Ep300


Sorted Z-values histogram for motif Ep300

Sorted Z-values for motif Ep300



Network of associatons between targets according to the STRING database.



First level regulatory network of Ep300

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_98348404 3.177 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_+_125490688 2.487 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr8_-_84800344 1.809 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr7_+_96522342 1.328 ENSMUST00000129737.1
 Tenm4
teneurin transmembrane protein 4
chr16_-_52452465 1.317 ENSMUST00000170035.1
ENSMUST00000164728.1
 Alcam

activated leukocyte cell adhesion molecule

chr10_+_58813359 1.211 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr6_+_99692679 1.197 ENSMUST00000101122.1
 Gpr27
G protein-coupled receptor 27
chr16_-_52452654 1.115 ENSMUST00000168071.1
 Alcam
activated leukocyte cell adhesion molecule
chr6_-_136173492 0.955 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr10_-_63244135 0.904 ENSMUST00000054837.3
 1700120B22Rik
RIKEN cDNA 1700120B22 gene
chr2_+_25054355 0.769 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
 Nsmf



NMDA receptor synaptonuclear signaling and neuronal migration factor



chr2_+_25054396 0.732 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
 Nsmf




NMDA receptor synaptonuclear signaling and neuronal migration factor




chr12_+_84009481 0.713 ENSMUST00000168120.1
 Acot1
acyl-CoA thioesterase 1
chr9_-_29411736 0.706 ENSMUST00000115236.1
 Ntm
neurotrimin
chr2_-_31845925 0.693 ENSMUST00000028188.7
 Fibcd1
fibrinogen C domain containing 1
chr18_+_51117754 0.679 ENSMUST00000116639.2
 Prr16
proline rich 16
chr1_-_87573825 0.673 ENSMUST00000068681.5
 Ngef
neuronal guanine nucleotide exchange factor
chr5_-_39644597 0.664 ENSMUST00000152057.1
 Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr3_-_88950401 0.656 ENSMUST00000090938.4
 Dap3
death associated protein 3
chr2_+_163602331 0.630 ENSMUST00000152135.1
 Ttpal
tocopherol (alpha) transfer protein-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 2.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 2.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 1.5 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.3 1.3 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 1.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.4 1.2 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 1.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.7 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 1.8 GO:0097440 apical dendrite(GO:0097440)
0.0 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 1.2 GO:0032127 dense core granule membrane(GO:0032127)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.4 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.2 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.5 2.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.2 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 0.7 GO:0008061 chitin binding(GO:0008061)
0.0 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 0.5 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)