Motif ID: Hnf1b

Z-value: 0.474


Transcription factors associated with Hnf1b:

Gene SymbolEntrez IDGene Name
Hnf1b ENSMUSG00000020679.5 Hnf1b



Activity profile for motif Hnf1b.

activity profile for motif Hnf1b


Sorted Z-values histogram for motif Hnf1b

Sorted Z-values for motif Hnf1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 106 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_53286052 1.931 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr13_+_4191163 1.852 ENSMUST00000021634.2
 Akr1c13
aldo-keto reductase family 1, member C13
chr1_-_158814469 1.703 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr4_+_43957401 1.240 ENSMUST00000030202.7
 Glipr2
GLI pathogenesis-related 2
chr9_+_53771499 0.994 ENSMUST00000048670.8
 Slc35f2
solute carrier family 35, member F2
chr12_+_58211772 0.958 ENSMUST00000110671.2
ENSMUST00000044299.2
 Sstr1

somatostatin receptor 1

chr13_+_4233730 0.955 ENSMUST00000081326.6
 Akr1c19
aldo-keto reductase family 1, member C19
chr2_+_158768083 0.893 ENSMUST00000029183.2
 Fam83d
family with sequence similarity 83, member D
chr7_+_100537192 0.880 ENSMUST00000120454.1
 Coa4
cytochrome c oxidase assembly factor 4
chr1_+_133309778 0.800 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
 Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr19_+_23723279 0.705 ENSMUST00000067077.1
 Gm9938
predicted gene 9938
chr12_+_5411641 0.668 ENSMUST00000163627.1
 2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr12_+_108605757 0.631 ENSMUST00000109854.2
 Evl
Ena-vasodilator stimulated phosphoprotein
chr5_-_123666682 0.605 ENSMUST00000149410.1
 Clip1
CAP-GLY domain containing linker protein 1
chr15_-_103215285 0.559 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
 Cbx5


chromobox 5


chr7_+_141216626 0.514 ENSMUST00000141804.1
ENSMUST00000148975.1
 Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr6_-_102464667 0.478 ENSMUST00000032159.6
 Cntn3
contactin 3
chr7_+_24862193 0.474 ENSMUST00000052897.4
ENSMUST00000170837.2
 Gm9844
Gm9844
predicted pseudogene 9844
predicted pseudogene 9844
chr9_+_99629496 0.474 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr17_-_35132050 0.455 ENSMUST00000025249.6
 Apom
apolipoprotein M

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 1.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 1.7 GO:0060349 bone morphogenesis(GO:0060349)
0.0 1.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 1.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.9 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 0.8 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.2 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.1 0.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.4 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.4 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) motor learning(GO:0061743) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.9 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.1 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.3 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.3 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.3 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)