Motif ID: Rfx2_Rfx7

Z-value: 1.268

Transcription factors associated with Rfx2_Rfx7:

Gene SymbolEntrez IDGene Name
Rfx2 ENSMUSG00000024206.8 Rfx2
Rfx7 ENSMUSG00000037674.9 Rfx7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx2mm10_v2_chr17_-_56830916_568310080.821.4e-06Click!
Rfx7mm10_v2_chr9_+_72532214_725322710.154.9e-01Click!


Activity profile for motif Rfx2_Rfx7.

activity profile for motif Rfx2_Rfx7


Sorted Z-values histogram for motif Rfx2_Rfx7

Sorted Z-values for motif Rfx2_Rfx7



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx2_Rfx7

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_52791179 5.307 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160
chr2_-_28466266 5.065 ENSMUST00000127683.1
ENSMUST00000086370.4
 1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr12_-_40038025 4.936 ENSMUST00000101472.3
 Arl4a
ADP-ribosylation factor-like 4A
chr13_+_112993868 4.407 ENSMUST00000092089.4
 Mcidas
multiciliate differentiation and DNA synthesis associated cell cycle protein
chr14_-_37098211 4.071 ENSMUST00000022337.9
 Cdhr1
cadherin-related family member 1
chr5_-_128953303 3.940 ENSMUST00000111346.1
 Rimbp2
RIMS binding protein 2
chr7_-_31051431 3.900 ENSMUST00000073892.4
 Fxyd7
FXYD domain-containing ion transport regulator 7
chr2_-_21205342 3.772 ENSMUST00000027992.2
 Enkur
enkurin, TRPC channel interacting protein
chr8_+_116504973 3.453 ENSMUST00000078170.5
 Dynlrb2
dynein light chain roadblock-type 2
chr18_+_75820174 3.374 ENSMUST00000058997.7
 Zbtb7c
zinc finger and BTB domain containing 7C
chr5_+_27261916 3.185 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr8_+_94772009 3.111 ENSMUST00000034230.5
 Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr11_+_100545607 3.066 ENSMUST00000092684.5
ENSMUST00000006976.7
 Ttc25

tetratricopeptide repeat domain 25

chr11_-_77725281 3.020 ENSMUST00000078623.4
 Cryba1
crystallin, beta A1
chr2_-_151980135 2.773 ENSMUST00000062047.5
 Fam110a
family with sequence similarity 110, member A
chr8_+_39005880 2.653 ENSMUST00000169034.1
 Tusc3
tumor suppressor candidate 3
chr5_+_30281377 2.601 ENSMUST00000101448.3
 Drc1
dynein regulatory complex subunit 1
chr11_-_97041395 2.539 ENSMUST00000021251.6
 Lrrc46
leucine rich repeat containing 46
chr13_-_3918157 2.529 ENSMUST00000091853.4
 Net1
neuroepithelial cell transforming gene 1
chr11_-_58801944 2.317 ENSMUST00000094156.4
ENSMUST00000060581.3
 Fam183b

family with sequence similarity 183, member B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.8 GO:0044458 motile cilium assembly(GO:0044458)
0.2 5.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.5 4.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 4.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.1 3.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.6 3.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 3.5 GO:0050890 cognition(GO:0050890)
0.4 3.4 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 3.2 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 3.2 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.8 3.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.4 3.1 GO:2000822 regulation of fear response(GO:1903365) regulation of behavioral fear response(GO:2000822)
0.0 2.7 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.2 2.5 GO:0051451 myoblast migration(GO:0051451)
0.5 2.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.5 1.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.9 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.8 GO:0042407 cristae formation(GO:0042407)
0.0 1.7 GO:0007605 sensory perception of sound(GO:0007605)
0.2 1.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 4.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 4.3 GO:0060170 ciliary membrane(GO:0060170)
0.3 4.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 3.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.9 GO:0031514 motile cilium(GO:0031514)
0.0 2.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 2.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.7 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 2.0 GO:0015030 Cajal body(GO:0015030)
0.2 1.8 GO:0061617 MICOS complex(GO:0061617)
0.1 1.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.5 GO:0000776 kinetochore(GO:0000776)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 1.3 GO:0001520 outer dense fiber(GO:0001520)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.2 GO:0003924 GTPase activity(GO:0003924)
0.5 5.8 GO:0031996 thioesterase binding(GO:0031996)
0.3 4.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 3.7 GO:0051117 ATPase binding(GO:0051117)
0.0 3.4 GO:0003774 motor activity(GO:0003774)
0.0 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 3.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.8 2.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 2.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.5 1.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.9 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.9 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.7 GO:0070064 proline-rich region binding(GO:0070064)
0.5 1.5 GO:0004335 galactokinase activity(GO:0004335)
0.2 1.5 GO:0051434 BH3 domain binding(GO:0051434)
0.5 1.4 GO:0001847 opsonin receptor activity(GO:0001847)