Motif ID: Etv4

Z-value: 0.441


Transcription factors associated with Etv4:

Gene SymbolEntrez IDGene Name
Etv4 ENSMUSG00000017724.8 Etv4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv4mm10_v2_chr11_-_101785252_1017853710.213.4e-01Click!


Activity profile for motif Etv4.

activity profile for motif Etv4


Sorted Z-values histogram for motif Etv4

Sorted Z-values for motif Etv4



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66969616 0.928 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
 Ndrg1



N-myc downstream regulated gene 1



chr15_-_66812593 0.832 ENSMUST00000100572.3
 Sla
src-like adaptor
chr9_+_107935876 0.786 ENSMUST00000035700.8
 Camkv
CaM kinase-like vesicle-associated
chr6_+_5725639 0.717 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_115134899 0.708 ENSMUST00000009538.5
ENSMUST00000169345.1
 Syn2

synapsin II

chr7_-_27181149 0.678 ENSMUST00000071986.6
ENSMUST00000121848.1
 Mia

melanoma inhibitory activity

chr3_+_123267445 0.647 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr1_-_56969864 0.605 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr3_-_87768932 0.602 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
 Pear1




platelet endothelial aggregation receptor 1




chr9_-_40346290 0.591 ENSMUST00000121357.1
 Gramd1b
GRAM domain containing 1B
chr2_+_32646586 0.566 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr11_+_101245996 0.562 ENSMUST00000129680.1
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr6_+_125552948 0.560 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr2_-_92024502 0.508 ENSMUST00000028663.4
 Creb3l1
cAMP responsive element binding protein 3-like 1
chr11_-_59163281 0.504 ENSMUST00000069631.2
 Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr1_-_191318090 0.499 ENSMUST00000046770.9
 Nenf
neuron derived neurotrophic factor
chr17_+_3397189 0.499 ENSMUST00000072156.6
 Tiam2
T cell lymphoma invasion and metastasis 2
chr1_-_56969827 0.495 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr11_-_48816936 0.489 ENSMUST00000140800.1
 Trim41
tripartite motif-containing 41
chr4_-_118489755 0.487 ENSMUST00000184261.1
 Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 171 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.0 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.8 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.8 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 0.6 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.6 GO:0001893 maternal placenta development(GO:0001893)
0.1 0.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.5 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.5 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.4 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.4 GO:0048680 neuron remodeling(GO:0016322) positive regulation of axon regeneration(GO:0048680)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 70 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.4 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.3 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 106 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 1.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 1.0 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.7 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)