Motif ID: Ebf1

Z-value: 1.274


Transcription factors associated with Ebf1:

Gene SymbolEntrez IDGene Name
Ebf1 ENSMUSG00000078561.3 Ebf1
Ebf1 ENSMUSG00000057098.8 Ebf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf1mm10_v2_chr11_+_44617310_44617336-0.164.8e-01Click!


Activity profile for motif Ebf1.

activity profile for motif Ebf1


Sorted Z-values histogram for motif Ebf1

Sorted Z-values for motif Ebf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_98053415 4.688 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr9_-_58313189 3.579 ENSMUST00000061799.8
 Loxl1
lysyl oxidase-like 1
chr2_-_25469742 3.010 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr11_+_115154139 2.756 ENSMUST00000021076.5
 Rab37
RAB37, member of RAS oncogene family
chr12_+_112620030 2.664 ENSMUST00000180015.1
ENSMUST00000021726.6
 Adssl1

adenylosuccinate synthetase like 1

chr2_-_25470031 2.642 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr16_+_18776839 2.272 ENSMUST00000043577.1
 Cldn5
claudin 5
chr2_-_180225812 2.257 ENSMUST00000015791.5
 Lama5
laminin, alpha 5
chr17_-_34000257 2.098 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
 H2-K1




histocompatibility 2, K1, K region




chr16_+_92498122 2.047 ENSMUST00000023670.3
 Clic6
chloride intracellular channel 6
chr1_-_156204998 2.039 ENSMUST00000015628.3
 Fam163a
family with sequence similarity 163, member A
chr9_-_40455670 1.992 ENSMUST00000165104.1
ENSMUST00000045682.5
 Gramd1b

GRAM domain containing 1B

chr10_+_58813359 1.949 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr1_-_156674290 1.944 ENSMUST00000079625.4
 Tor3a
torsin family 3, member A
chr6_+_141524379 1.906 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chrX_+_73757069 1.903 ENSMUST00000002079.6
 Plxnb3
plexin B3
chr2_+_22622183 1.878 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr7_-_45870928 1.865 ENSMUST00000146672.1
 Grin2d
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
chr19_-_57008187 1.785 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
 Afap1l2



actin filament associated protein 1-like 2



chr7_-_45103747 1.778 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 615 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 6.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.4 3.9 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.4 3.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.6 2.9 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 2.9 GO:0033692 cellular polysaccharide biosynthetic process(GO:0033692)
0.9 2.8 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.3 2.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.9 2.7 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 2.6 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.4 2.5 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.4 2.5 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.6 2.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 2.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.5 2.1 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 2.1 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.1 2.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 2.1 GO:0098661 inorganic anion transmembrane transport(GO:0098661)
1.0 2.0 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.4 2.0 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 2.0 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 200 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.1 GO:0005604 basement membrane(GO:0005604)
0.3 5.5 GO:0005605 basal lamina(GO:0005605)
0.1 5.5 GO:0005581 collagen trimer(GO:0005581)
0.0 4.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 4.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 4.3 GO:0034707 chloride channel complex(GO:0034707)
0.3 4.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 3.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.5 2.5 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 2.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.6 2.3 GO:0043259 laminin-10 complex(GO:0043259)
0.2 2.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 2.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 1.9 GO:0044292 dendrite terminus(GO:0044292)
0.6 1.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.3 1.7 GO:0005861 troponin complex(GO:0005861)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 373 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 5.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 5.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.9 GO:0005178 integrin binding(GO:0005178)
0.3 4.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 4.0 GO:0003924 GTPase activity(GO:0003924)
1.2 3.6 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.2 3.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 3.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 3.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 3.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.8 GO:0045296 cadherin binding(GO:0045296)
0.2 2.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 2.6 GO:0008201 heparin binding(GO:0008201)
0.3 2.5 GO:0015168 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.1 2.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.5 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.2 2.4 GO:0015026 coreceptor activity(GO:0015026)
0.2 2.3 GO:0044548 S100 protein binding(GO:0044548)
0.6 2.2 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)