Motif ID: Foxc1

Z-value: 0.822


Transcription factors associated with Foxc1:

Gene SymbolEntrez IDGene Name
Foxc1 ENSMUSG00000050295.2 Foxc1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxc1mm10_v2_chr13_+_31806627_31806650-0.125.9e-01Click!


Activity profile for motif Foxc1.

activity profile for motif Foxc1


Sorted Z-values histogram for motif Foxc1

Sorted Z-values for motif Foxc1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxc1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_+_1010543 4.282 ENSMUST00000091197.3
Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr15_-_66948419 3.398 ENSMUST00000167817.1
Ndrg1
N-myc downstream regulated gene 1
chr5_+_98854434 2.716 ENSMUST00000031278.4
Bmp3
bone morphogenetic protein 3
chr13_-_54766553 2.411 ENSMUST00000036825.7
Sncb
synuclein, beta
chr1_+_107511489 1.970 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr7_-_75308373 1.964 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr6_+_47244359 1.945 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr1_+_107511416 1.853 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_72824482 1.449 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr1_-_71653162 1.401 ENSMUST00000055226.6
Fn1
fibronectin 1
chr17_+_3397189 1.379 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr3_+_94377432 1.120 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr6_-_42324554 1.006 ENSMUST00000095974.3
Fam131b
family with sequence similarity 131, member B
chr3_+_94377505 0.963 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr2_+_4976113 0.936 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chrX_-_102252154 0.935 ENSMUST00000050551.3
Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr16_-_21947536 0.903 ENSMUST00000023562.7
Tmem41a
transmembrane protein 41a
chr6_-_42324640 0.870 ENSMUST00000031891.8
ENSMUST00000143278.1
Fam131b

family with sequence similarity 131, member B

chr2_-_172370506 0.866 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr8_-_13494479 0.831 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr8_+_106870827 0.800 ENSMUST00000176144.1
ENSMUST00000175987.1
Has3

hyaluronan synthase 3

chr5_+_8046077 0.798 ENSMUST00000088786.4
Sri
sorcin
chr12_+_44328882 0.784 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr3_+_124321031 0.764 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr17_+_80944611 0.764 ENSMUST00000025092.4
Tmem178
transmembrane protein 178
chr9_-_86880414 0.762 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
Snap91



synaptosomal-associated protein 91



chr17_-_36951338 0.750 ENSMUST00000173540.1
Ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr1_+_45311538 0.746 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr18_-_33463615 0.738 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr1_+_84839833 0.703 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr15_-_102667749 0.693 ENSMUST00000075630.3
Atp5g2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chrX_+_120290259 0.671 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
Pcdh11x


protocadherin 11 X-linked


chr3_-_141982224 0.657 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr10_+_77864623 0.646 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr17_-_70851710 0.632 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr13_+_53525703 0.619 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr9_-_106891401 0.609 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr11_-_45944910 0.589 ENSMUST00000129820.1
Lsm11
U7 snRNP-specific Sm-like protein LSM11
chr4_-_40948196 0.580 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chrX_-_102251852 0.577 ENSMUST00000101336.3
ENSMUST00000136277.1
Cited1

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

chr16_-_46155077 0.560 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr17_-_36951636 0.559 ENSMUST00000040402.7
ENSMUST00000174711.1
Ppp1r11

protein phosphatase 1, regulatory (inhibitor) subunit 11

chr13_-_8871751 0.557 ENSMUST00000175958.1
Wdr37
WD repeat domain 37
chr18_+_78349754 0.528 ENSMUST00000164064.1
Gm6133
predicted gene 6133
chr2_+_151542483 0.522 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr6_+_86371489 0.519 ENSMUST00000089558.5
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr13_-_49320219 0.513 ENSMUST00000110086.1
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr1_+_120602405 0.494 ENSMUST00000079721.7
En1
engrailed 1
chr7_-_89941084 0.474 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr2_-_126709567 0.472 ENSMUST00000099423.2
Gm10774
predicted pseudogene 10774
chr11_-_98625661 0.459 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr11_+_32300069 0.452 ENSMUST00000020535.1
Hbq1a
hemoglobin, theta 1A
chr15_+_6422240 0.438 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr5_-_97111565 0.437 ENSMUST00000112969.3
Paqr3
progestin and adipoQ receptor family member III
chr3_+_95124476 0.419 ENSMUST00000131597.1
ENSMUST00000005769.6
ENSMUST00000107227.1
Tmod4


tropomodulin 4


chr3_+_90079540 0.417 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
Tpm3


tropomyosin 3, gamma


chr12_+_105336922 0.417 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr6_-_29212240 0.414 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr17_+_46254017 0.400 ENSMUST00000095262.4
Lrrc73
leucine rich repeat containing 73
chr3_-_95282076 0.392 ENSMUST00000015855.7
Prune
prune homolog (Drosophila)
chr17_+_45686322 0.388 ENSMUST00000024734.7
Mrpl14
mitochondrial ribosomal protein L14
chr14_+_113314602 0.385 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr15_-_102257449 0.384 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr11_-_102296618 0.382 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr2_-_79908389 0.370 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr5_-_149636164 0.359 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr2_+_35622010 0.357 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr15_+_80255184 0.353 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr8_-_25840440 0.352 ENSMUST00000110609.1
Ash2l
ash2 (absent, small, or homeotic)-like (Drosophila)
chr3_-_89998656 0.351 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr15_+_80623499 0.350 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr14_-_31128924 0.348 ENSMUST00000064032.4
ENSMUST00000049732.5
ENSMUST00000090205.3
Smim4


small itegral membrane protein 4


chr11_+_70017085 0.348 ENSMUST00000108589.2
Dlg4
discs, large homolog 4 (Drosophila)
chr2_-_156839790 0.345 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr16_-_97170707 0.339 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr3_+_145987835 0.334 ENSMUST00000039517.6
Syde2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr4_-_59783800 0.333 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr6_-_88045190 0.333 ENSMUST00000113596.1
ENSMUST00000113600.3
Rab7

RAB7, member RAS oncogene family

chr2_-_12301914 0.333 ENSMUST00000028106.4
Itga8
integrin alpha 8
chr7_+_16309577 0.332 ENSMUST00000002152.6
Bbc3
BCL2 binding component 3
chr9_-_86880647 0.332 ENSMUST00000167014.1
Snap91
synaptosomal-associated protein 91
chr1_+_74284930 0.330 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr3_-_96197580 0.329 ENSMUST00000016087.3
Bola1
bolA-like 1 (E. coli)
chr13_-_34077992 0.322 ENSMUST00000056427.8
Tubb2a
tubulin, beta 2A class IIA
chr2_-_79908428 0.317 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr8_-_41417042 0.313 ENSMUST00000033999.6
Frg1
FSHD region gene 1
chr2_+_30807826 0.305 ENSMUST00000041830.3
ENSMUST00000152374.1
Ntmt1

N-terminal Xaa-Pro-Lys N-methyltransferase 1

chr9_+_72806874 0.302 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr11_-_78550777 0.297 ENSMUST00000103242.4
Tmem97
transmembrane protein 97
chr2_-_103485068 0.287 ENSMUST00000111168.3
Cat
catalase
chr13_+_46669517 0.286 ENSMUST00000099547.3
C78339
expressed sequence C78339
chr15_-_76656905 0.281 ENSMUST00000176274.1
Cyhr1
cysteine and histidine rich 1
chr12_-_73047179 0.258 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr7_+_44816088 0.258 ENSMUST00000057195.9
ENSMUST00000107891.1
Nup62

nucleoporin 62

chr13_+_42680565 0.255 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr9_-_71592265 0.249 ENSMUST00000169573.1
ENSMUST00000166843.1
ENSMUST00000163998.1
Myzap
Gcom1

myocardial zonula adherens protein
GRINL1A complex locus

chr19_-_53944621 0.239 ENSMUST00000135402.2
Bbip1
BBSome interacting protein 1
chr4_-_43030440 0.236 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr4_+_40948401 0.234 ENSMUST00000030128.5
Chmp5
charged multivesicular body protein 5
chr10_-_14705459 0.231 ENSMUST00000149485.1
ENSMUST00000154132.1
Vta1

Vps20-associated 1 homolog (S. cerevisiae)

chr7_-_44892358 0.230 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr17_-_83631892 0.221 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr15_-_82244716 0.220 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr12_-_69198419 0.219 ENSMUST00000021356.5
Dnaaf2
dynein, axonemal assembly factor 2
chr11_+_6415443 0.218 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr16_-_59632520 0.213 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr3_+_61364507 0.209 ENSMUST00000049064.2
Rap2b
RAP2B, member of RAS oncogene family
chr1_+_34439851 0.208 ENSMUST00000027303.7
Imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr4_+_117550326 0.186 ENSMUST00000037127.8
Eri3
exoribonuclease 3
chr9_+_110419750 0.182 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chr13_-_107414742 0.178 ENSMUST00000061241.6
Apoo-ps
apolipoprotein O, pseudogene
chr18_-_78123324 0.178 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr11_+_3202612 0.177 ENSMUST00000110049.1
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr13_+_23934434 0.176 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chrX_-_101222426 0.170 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr12_+_4234023 0.165 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr1_-_74284636 0.161 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr2_+_30237680 0.158 ENSMUST00000113654.1
ENSMUST00000095078.2
Lrrc8a

leucine rich repeat containing 8A

chr14_-_48662740 0.155 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr17_-_57011271 0.149 ENSMUST00000002733.6
Gtf2f1
general transcription factor IIF, polypeptide 1
chr9_-_67049143 0.146 ENSMUST00000113687.1
ENSMUST00000113693.1
ENSMUST00000113701.1
ENSMUST00000034928.5
ENSMUST00000113685.3
ENSMUST00000030185.4
ENSMUST00000050905.9
ENSMUST00000113705.1
ENSMUST00000113697.1
ENSMUST00000113707.2
Tpm1









tropomyosin 1, alpha









chr2_+_163994960 0.144 ENSMUST00000018470.3
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr13_-_54611332 0.142 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr1_-_131097535 0.140 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr6_+_68161415 0.139 ENSMUST00000168090.1
Igkv1-115
immunoglobulin kappa variable 1-115
chr17_+_16972910 0.139 ENSMUST00000071374.5
BC002059
cDNA sequence BC002059
chr11_-_4594750 0.136 ENSMUST00000109943.3
Mtmr3
myotubularin related protein 3
chr11_+_70017199 0.134 ENSMUST00000133140.1
Dlg4
discs, large homolog 4 (Drosophila)
chr16_+_35983424 0.133 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr8_+_69088646 0.129 ENSMUST00000006435.7
Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
chr11_-_96829959 0.128 ENSMUST00000081775.5
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr7_+_83584910 0.128 ENSMUST00000039317.7
ENSMUST00000164944.1
Tmc3

transmembrane channel-like gene family 3

chr5_+_134099704 0.118 ENSMUST00000016088.8
Gatsl2
GATS protein-like 2
chr7_-_127026479 0.117 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_-_94370450 0.112 ENSMUST00000138514.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_-_111082997 0.108 ENSMUST00000161051.1
ENSMUST00000160132.1
ENSMUST00000106666.3
ENSMUST00000162415.1
Eif4g2



eukaryotic translation initiation factor 4, gamma 2



chr11_+_68968107 0.107 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr13_-_54611274 0.105 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr1_+_189728264 0.093 ENSMUST00000097442.2
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr9_-_21037775 0.085 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr19_+_7268296 0.080 ENSMUST00000066646.4
Rcor2
REST corepressor 2
chr15_+_88819584 0.071 ENSMUST00000024042.3
Creld2
cysteine-rich with EGF-like domains 2
chr7_+_119760918 0.067 ENSMUST00000106527.1
ENSMUST00000106528.1
ENSMUST00000063770.3
ENSMUST00000106529.1
Acsm3



acyl-CoA synthetase medium-chain family member 3



chr3_+_154597197 0.066 ENSMUST00000155385.1
ENSMUST00000029850.8
Cryz

crystallin, zeta

chr6_-_55175019 0.066 ENSMUST00000003569.5
Inmt
indolethylamine N-methyltransferase
chr7_-_44816586 0.058 ENSMUST00000047356.8
Atf5
activating transcription factor 5
chr11_+_69935796 0.058 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr6_-_99096196 0.056 ENSMUST00000175886.1
Foxp1
forkhead box P1
chr1_+_75236439 0.051 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr11_-_74724670 0.048 ENSMUST00000021091.8
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr2_+_73312601 0.044 ENSMUST00000090811.4
ENSMUST00000112050.1
Scrn3

secernin 3

chr18_+_33464163 0.041 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr3_+_95160449 0.038 ENSMUST00000090823.1
ENSMUST00000090821.3
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr11_+_101082565 0.032 ENSMUST00000001806.3
ENSMUST00000107308.3
Coasy

Coenzyme A synthase

chr15_+_10177623 0.028 ENSMUST00000124470.1
Prlr
prolactin receptor
chr6_+_55203381 0.021 ENSMUST00000053094.7
Fam188b
family with sequence similarity 188, member B
chr9_-_83146601 0.021 ENSMUST00000162246.2
ENSMUST00000161796.2
Hmgn3

high mobility group nucleosomal binding domain 3

chr16_+_58727910 0.014 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr13_-_18382041 0.013 ENSMUST00000139064.2
ENSMUST00000175703.2
Pou6f2

POU domain, class 6, transcription factor 2

chr8_-_105933832 0.011 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr5_-_97111589 0.007 ENSMUST00000069453.2
ENSMUST00000112968.1
Paqr3

progestin and adipoQ receptor family member III

chr5_-_100038869 0.003 ENSMUST00000153442.1
Hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161)
0.4 1.9 GO:0071205 clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205)
0.4 1.5 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.3 3.4 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.3 4.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 2.1 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.3 0.8 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) hematopoietic stem cell migration(GO:0035701) regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.3 0.8 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 0.9 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.2 0.6 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.2 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.5 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.2 0.5 GO:0061743 motor learning(GO:0061743)
0.2 0.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.8 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.3 GO:0061724 lipophagy(GO:0061724)
0.1 0.3 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.2 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.1 1.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 2.7 GO:0042417 dopamine metabolic process(GO:0042417)
0.1 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 2.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.2 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.0 0.8 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.7 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 0.5 GO:2000821 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.2 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.0 3.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.3 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 2.1 GO:0098792 xenophagy(GO:0098792)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.5 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.8 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 2.0 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.3 0.9 GO:0042585 germinal vesicle(GO:0042585)
0.3 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 2.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 3.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.5 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 3.4 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) alveolar lamellar body(GO:0097208)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613) Flemming body(GO:0090543)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0048188 MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 2.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0008142 oxysterol binding(GO:0008142)
0.3 2.7 GO:0070700 BMP receptor binding(GO:0070700)
0.3 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 1.4 GO:0045340 mercury ion binding(GO:0045340)
0.2 0.6 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 1.5 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.8 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.1 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 3.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.8 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.1 0.2 GO:0030519 snoRNP binding(GO:0030519)
0.1 2.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 4.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.5 GO:0048185 activin binding(GO:0048185)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.5 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 2.7 GO:0002020 protease binding(GO:0002020)
0.0 0.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0004140 dephospho-CoA kinase activity(GO:0004140)