Motif ID: Msx3

Z-value: 0.353


Transcription factors associated with Msx3:

Gene SymbolEntrez IDGene Name
Msx3 ENSMUSG00000025469.9 Msx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Msx3mm10_v2_chr7_-_140049140_1400491800.077.4e-01Click!


Activity profile for motif Msx3.

activity profile for motif Msx3


Sorted Z-values histogram for motif Msx3

Sorted Z-values for motif Msx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Msx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_44787746 0.577 ENSMUST00000181839.1
 2310069G16Rik
RIKEN cDNA 2310069G16 gene
chr4_+_102254739 0.406 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr3_-_116253467 0.397 ENSMUST00000090473.5
 Gpr88
G-protein coupled receptor 88
chr2_-_45117349 0.390 ENSMUST00000176438.2
 Zeb2
zinc finger E-box binding homeobox 2
chr4_-_14621805 0.382 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr2_+_125136692 0.344 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr2_-_160619971 0.281 ENSMUST00000109473.1
 Gm14221
predicted gene 14221
chr18_+_57468478 0.280 ENSMUST00000091892.2
 Ctxn3
cortexin 3
chr10_+_81257277 0.273 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
 Matk


megakaryocyte-associated tyrosine kinase


chr4_+_94739276 0.250 ENSMUST00000073939.6
ENSMUST00000102798.1
 Tek

endothelial-specific receptor tyrosine kinase

chr2_-_33086366 0.236 ENSMUST00000049618.2
 Garnl3
GTPase activating RANGAP domain-like 3
chr2_-_33087169 0.216 ENSMUST00000102810.3
 Garnl3
GTPase activating RANGAP domain-like 3
chr9_-_53975246 0.202 ENSMUST00000048409.7
 Elmod1
ELMO/CED-12 domain containing 1
chr7_-_127895578 0.155 ENSMUST00000033074.6
 Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr13_+_83732438 0.154 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chr12_+_102128718 0.153 ENSMUST00000159329.1
 Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_+_66985680 0.151 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1
chr1_+_104768510 0.149 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr4_-_14621494 0.139 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr11_+_53433299 0.138 ENSMUST00000018382.6
 Gdf9
growth differentiation factor 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.4 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.0 GO:0034457 Mpp10 complex(GO:0034457)

Gene overrepresentation in molecular_function category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.0 GO:0030519 snoRNP binding(GO:0030519)