Motif ID: Etv1_Etv5_Gabpa

Z-value: 1.215

Transcription factors associated with Etv1_Etv5_Gabpa:

Gene SymbolEntrez IDGene Name
Etv1 ENSMUSG00000004151.10 Etv1
Etv5 ENSMUSG00000013089.9 Etv5
Gabpa ENSMUSG00000008976.10 Gabpa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv5mm10_v2_chr16_-_22439719_22439733-0.602.5e-03Click!
Gabpamm10_v2_chr16_+_84835070_84835124-0.415.3e-02Click!
Etv1mm10_v2_chr12_+_38781093_387811290.203.5e-01Click!


Activity profile for motif Etv1_Etv5_Gabpa.

activity profile for motif Etv1_Etv5_Gabpa


Sorted Z-values histogram for motif Etv1_Etv5_Gabpa

Sorted Z-values for motif Etv1_Etv5_Gabpa



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv1_Etv5_Gabpa

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22161450 5.939 ENSMUST00000115379.1
 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr14_-_31494992 3.161 ENSMUST00000055303.3
 Mettl6
methyltransferase like 6
chr18_+_62548911 3.060 ENSMUST00000055725.4
ENSMUST00000162365.1
 Spink10

serine peptidase inhibitor, Kazal type 10

chr11_-_94653964 2.923 ENSMUST00000039949.4
 Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr2_+_5845243 2.668 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr19_+_5366764 2.617 ENSMUST00000025759.7
 Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr2_+_74825802 2.414 ENSMUST00000028511.7
 Mtx2
metaxin 2
chr4_+_118409331 2.296 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr11_-_97041395 2.293 ENSMUST00000021251.6
 Lrrc46
leucine rich repeat containing 46
chr11_+_101316200 2.272 ENSMUST00000142640.1
ENSMUST00000019470.7
 Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr2_+_164805082 2.214 ENSMUST00000052107.4
 Zswim3
zinc finger SWIM-type containing 3
chr7_-_127042420 2.111 ENSMUST00000032915.6
 Kif22
kinesin family member 22
chr4_-_45320580 2.079 ENSMUST00000030003.3
 Exosc3
exosome component 3
chr9_-_96889381 2.073 ENSMUST00000112951.2
ENSMUST00000126411.1
ENSMUST00000078478.1
ENSMUST00000119141.1
ENSMUST00000120101.1
 Acpl2




acid phosphatase-like 2




chr6_+_34354119 2.048 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chr6_-_56704673 2.000 ENSMUST00000170382.2
 Lsm5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_118814237 1.969 ENSMUST00000028803.7
ENSMUST00000126045.1
 Knstrn

kinetochore-localized astrin/SPAG5 binding

chr10_-_18023229 1.965 ENSMUST00000020002.7
 Abracl
ABRA C-terminal like
chr9_-_105395237 1.964 ENSMUST00000140851.1
 Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr2_-_118256929 1.959 ENSMUST00000028820.6
ENSMUST00000028821.3
 Fsip1

fibrous sheath-interacting protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 596 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.4 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 10.0 GO:0051028 mRNA transport(GO:0051028)
0.1 8.8 GO:0006413 translational initiation(GO:0006413)
0.2 7.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.4 6.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 6.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.4 5.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.3 5.3 GO:0045116 protein neddylation(GO:0045116)
0.2 4.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 4.7 GO:0032543 mitochondrial translation(GO:0032543)
0.1 4.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.4 4.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 4.1 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.2 4.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 4.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 4.0 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.5 3.8 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 3.7 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.8 3.3 GO:0030576 Cajal body organization(GO:0030576)
0.5 3.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 271 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 14.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 9.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 9.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 6.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 6.4 GO:0035371 microtubule plus-end(GO:0035371)
0.6 6.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.5 5.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 5.0 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 5.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 4.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 4.2 GO:0005871 kinesin complex(GO:0005871)
0.5 4.0 GO:0005818 aster(GO:0005818)
0.1 4.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.5 3.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 3.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.7 3.7 GO:0005683 U7 snRNP(GO:0005683)
0.2 3.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 3.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 3.4 GO:0005839 proteasome core complex(GO:0005839)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 369 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 24.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 12.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 6.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 6.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.4 5.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 5.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.6 4.9 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.6 4.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 4.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5 4.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 4.3 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 4.2 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 4.2 GO:0005525 GTP binding(GO:0005525)
0.8 4.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 4.0 GO:0031491 nucleosome binding(GO:0031491)
0.4 3.9 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 3.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.3 3.8 GO:0031386 protein tag(GO:0031386)
0.0 3.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.5 3.5 GO:1990446 U1 snRNP binding(GO:1990446)