Motif ID: Mafa

Z-value: 0.536


Transcription factors associated with Mafa:

Gene SymbolEntrez IDGene Name
Mafa ENSMUSG00000047591.4 Mafa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafamm10_v2_chr15_-_75747922_757479220.378.1e-02Click!


Activity profile for motif Mafa.

activity profile for motif Mafa


Sorted Z-values histogram for motif Mafa

Sorted Z-values for motif Mafa



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafa

PNG image of the network

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Top targets:


Showing 1 to 20 of 73 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_102254739 1.507 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr11_-_66525964 1.349 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chr9_-_98032983 1.318 ENSMUST00000162295.1
Clstn2
calsyntenin 2
chr16_-_17576631 1.164 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4


solute carrier family 7 (cationic amino acid transporter, y+ system), member 4


chr10_-_84440591 0.967 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr1_-_136260873 0.876 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr12_-_75177325 0.814 ENSMUST00000042299.2
Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr4_+_102254993 0.813 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chrX_-_73869804 0.812 ENSMUST00000066576.5
ENSMUST00000114430.1
L1cam

L1 cell adhesion molecule

chr11_-_66525795 0.812 ENSMUST00000123454.1
Shisa6
shisa homolog 6 (Xenopus laevis)
chrX_+_104482774 0.795 ENSMUST00000087867.5
Uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr4_+_21931291 0.793 ENSMUST00000029908.7
Faxc
failed axon connections homolog (Drosophila)
chr1_-_169747634 0.750 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr14_+_119138415 0.671 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr9_-_98033181 0.665 ENSMUST00000035027.6
Clstn2
calsyntenin 2
chr10_+_58813359 0.661 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr8_-_70487314 0.652 ENSMUST00000045286.7
Tmem59l
transmembrane protein 59-like
chr19_+_27217011 0.598 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr5_+_111417263 0.591 ENSMUST00000094463.4
Mn1
meningioma 1
chr16_-_74411776 0.580 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 2.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.2 1.0 GO:0034436 glycoprotein transport(GO:0034436)
0.1 1.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.3 0.8 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 0.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.8 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.6 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.4 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.3 GO:0048133 NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0001527 microfibril(GO:0001527)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0030552 cAMP binding(GO:0030552)
0.0 1.2 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.3 1.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.2 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)