Motif ID: Hoxb5

Z-value: 0.675


Transcription factors associated with Hoxb5:

Gene SymbolEntrez IDGene Name
Hoxb5 ENSMUSG00000038700.3 Hoxb5



Activity profile for motif Hoxb5.

activity profile for motif Hoxb5


Sorted Z-values histogram for motif Hoxb5

Sorted Z-values for motif Hoxb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb5

PNG image of the network

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Top targets:


Showing 1 to 20 of 86 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_125532377 5.034 ENSMUST00000031446.6
 Tmem132b
transmembrane protein 132B
chr3_-_85722474 3.395 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr6_-_18514802 3.370 ENSMUST00000090601.5
 Cttnbp2
cortactin binding protein 2
chr17_+_35076902 2.987 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr1_-_56971762 2.924 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr17_+_35077080 2.839 ENSMUST00000172959.1
 Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr4_+_11704439 1.560 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr5_-_114273702 1.513 ENSMUST00000144050.1
ENSMUST00000044790.5
 Foxn4

forkhead box N4

chr6_+_141249161 1.437 ENSMUST00000043259.7
 Pde3a
phosphodiesterase 3A, cGMP inhibited
chrX_-_10117597 1.367 ENSMUST00000115543.2
ENSMUST00000044789.3
ENSMUST00000115544.2
 Srpx


sushi-repeat-containing protein


chr11_+_74619594 1.355 ENSMUST00000100866.2
 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr2_+_85136355 1.235 ENSMUST00000057019.7
 Aplnr
apelin receptor
chr2_+_116067933 1.148 ENSMUST00000156095.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr12_-_78983476 1.092 ENSMUST00000070174.7
 Tmem229b
transmembrane protein 229B
chr12_-_78980758 1.078 ENSMUST00000174072.1
 Tmem229b
transmembrane protein 229B
chr10_+_128909866 1.033 ENSMUST00000026407.7
 Cd63
CD63 antigen
chrX_+_7723278 1.031 ENSMUST00000144148.1
 Wdr45
WD repeat domain 45
chr3_-_103737995 0.929 ENSMUST00000029440.8
 Olfml3
olfactomedin-like 3
chr10_-_127211528 0.835 ENSMUST00000013970.7
 Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr7_+_45017953 0.819 ENSMUST00000044111.7
 Rras
Harvey rat sarcoma oncogene, subgroup R

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.2 2.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.6 GO:0051310 metaphase plate congression(GO:0051310)
0.2 1.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.5 1.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 1.4 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.4 1.3 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.1 1.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 1.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 1.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.3 0.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.8 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.6 GO:0006023 aminoglycan biosynthetic process(GO:0006023)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0040031 snRNA modification(GO:0040031)
0.1 0.4 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.2 GO:0005776 autophagosome(GO:0005776)
0.0 1.6 GO:0051233 spindle midzone(GO:0051233)
0.2 1.3 GO:0000322 storage vacuole(GO:0000322)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 1.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.6 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 5.8 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.4 3.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 2.4 GO:0019003 GDP binding(GO:0019003)
0.0 1.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.4 GO:0030552 cAMP binding(GO:0030552)
0.3 1.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 1.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 0.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 0.8 GO:0019966 C-X-C chemokine binding(GO:0019958) interleukin-1 binding(GO:0019966) tumor necrosis factor binding(GO:0043120)
0.0 0.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.2 GO:0030249 guanylate cyclase regulator activity(GO:0030249)