Motif ID: Tbx1_Eomes

Z-value: 1.070

Transcription factors associated with Tbx1_Eomes:

Gene SymbolEntrez IDGene Name
Eomes ENSMUSG00000032446.8 Eomes
Tbx1 ENSMUSG00000009097.9 Tbx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Eomesmm10_v2_chr9_+_118478851_118478866-0.106.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx1_Eomes

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 19.406 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr2_-_13011747 12.696 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr1_+_6730051 10.056 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr1_-_138847579 8.389 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr1_+_6730135 6.831 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr2_-_57114970 5.987 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr17_+_29093763 5.007 ENSMUST00000023829.6
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr4_-_35845204 4.956 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr7_-_28302238 4.929 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr6_+_15196949 4.847 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr1_+_132316112 4.524 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chr4_+_125490688 4.486 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr9_-_43239816 4.393 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr6_-_94700137 3.675 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr12_+_3891728 3.443 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr6_+_7555053 3.438 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr1_+_153665274 3.275 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr18_-_46212595 3.249 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr1_+_153665666 2.869 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr18_+_60963517 2.813 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chrX_+_142681398 2.765 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
Tmem164



transmembrane protein 164



chr2_+_164562579 2.655 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr7_-_141443989 2.569 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr1_+_153665587 2.462 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 2.377 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr4_-_134018829 2.340 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr19_+_20601958 2.249 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr13_-_43304153 1.872 ENSMUST00000055341.5
Gfod1
glucose-fructose oxidoreductase domain containing 1
chr17_+_48932368 1.620 ENSMUST00000046254.2
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chr10_-_120899067 1.617 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr10_-_92162753 1.442 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr5_-_24329556 1.425 ENSMUST00000115098.2
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_170214826 1.376 ENSMUST00000159201.1
ENSMUST00000055830.1
4930500M09Rik

RIKEN cDNA 4930500M09 gene

chr8_+_106870827 1.355 ENSMUST00000176144.1
ENSMUST00000175987.1
Has3

hyaluronan synthase 3

chr1_-_69108039 1.285 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr7_-_4546567 1.248 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr13_-_89742490 1.244 ENSMUST00000109546.2
Vcan
versican
chr17_-_70849644 1.233 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr9_-_69760924 1.203 ENSMUST00000071281.4
Foxb1
forkhead box B1
chr1_+_131970589 1.158 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr5_+_115908644 1.114 ENSMUST00000141101.1
Cit
citron
chr17_-_29237759 1.089 ENSMUST00000137727.1
ENSMUST00000024805.7
Cpne5

copine V

chr8_-_8639363 1.080 ENSMUST00000152698.1
Efnb2
ephrin B2
chr4_-_132510493 1.067 ENSMUST00000030724.8
Sesn2
sestrin 2
chr4_+_42950369 1.043 ENSMUST00000084662.5
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_+_96629919 0.944 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr1_-_174921813 0.926 ENSMUST00000055294.3
Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr11_+_98348404 0.921 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr9_+_15239045 0.921 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr4_-_49845549 0.890 ENSMUST00000093859.4
ENSMUST00000076674.3
Grin3a

glutamate receptor ionotropic, NMDA3A

chr2_+_54436317 0.841 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
Galnt13


UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13


chr3_+_55461758 0.839 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chrX_-_152016269 0.838 ENSMUST00000026288.4
Ribc1
RIB43A domain with coiled-coils 1
chrX_-_53269020 0.805 ENSMUST00000114838.1
Fam122b
family with sequence similarity 122, member B
chr9_-_95845215 0.771 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr2_+_27079371 0.753 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr10_-_85916902 0.753 ENSMUST00000037646.7
Prdm4
PR domain containing 4
chr10_+_56377300 0.749 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr16_-_9994921 0.738 ENSMUST00000115835.1
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr2_+_138278481 0.709 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chr6_+_50110837 0.662 ENSMUST00000167628.1
Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr4_-_123750236 0.659 ENSMUST00000102636.3
Akirin1
akirin 1
chr4_+_43641262 0.657 ENSMUST00000123351.1
ENSMUST00000128549.1
Npr2

natriuretic peptide receptor 2

chr1_+_164115264 0.649 ENSMUST00000162746.1
Selp
selectin, platelet
chr1_-_126830632 0.629 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr14_-_51988829 0.613 ENSMUST00000181008.1
Gm16617
predicted gene, 16617
chr6_-_24956106 0.563 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr7_+_127746775 0.556 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr3_+_75557530 0.553 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr10_+_80930071 0.541 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr3_+_102734496 0.533 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chr1_-_105356658 0.524 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152

ring finger protein 152

chr7_-_115824699 0.504 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr3_+_40950631 0.498 ENSMUST00000048490.6
Larp1b
La ribonucleoprotein domain family, member 1B
chr10_-_128211788 0.495 ENSMUST00000061995.8
Spryd4
SPRY domain containing 4
chr7_-_114117761 0.476 ENSMUST00000069449.5
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr19_+_4097392 0.471 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chr5_+_120513102 0.470 ENSMUST00000111889.1
Slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr1_+_74236479 0.465 ENSMUST00000113820.2
ENSMUST00000006467.7
ENSMUST00000113819.1
Arpc2


actin related protein 2/3 complex, subunit 2


chr11_-_22286795 0.455 ENSMUST00000109563.2
ENSMUST00000180360.1
Ehbp1

EH domain binding protein 1

chrX_+_153006461 0.448 ENSMUST00000095755.3
Usp51
ubiquitin specific protease 51
chr2_-_25272380 0.418 ENSMUST00000028342.6
Ssna1
Sjogren's syndrome nuclear autoantigen 1
chr10_+_4710119 0.417 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr11_-_69681903 0.396 ENSMUST00000066760.1
Senp3
SUMO/sentrin specific peptidase 3
chr16_-_56024628 0.390 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr14_+_31251454 0.378 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1
chr1_-_126830786 0.378 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr9_+_87015537 0.360 ENSMUST00000058846.4
Ripply2
ripply2 homolog (zebrafish)
chr8_-_4259257 0.356 ENSMUST00000053252.7
Ctxn1
cortexin 1
chr19_+_6057925 0.347 ENSMUST00000179142.1
Fau
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr13_+_93304066 0.345 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr4_+_148000722 0.338 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chr12_+_78861693 0.334 ENSMUST00000071230.7
Eif2s1
eukaryotic translation initiation factor 2, subunit 1 alpha
chrM_+_7759 0.330 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr11_+_121237216 0.327 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr6_+_61180313 0.321 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr17_+_35135695 0.320 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
Bag6


BCL2-associated athanogene 6


chr15_+_10952332 0.315 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr4_+_117849361 0.315 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr14_+_56887795 0.310 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr7_-_30563184 0.301 ENSMUST00000043898.6
Psenen
presenilin enhancer 2 homolog (C. elegans)
chr2_-_148046896 0.286 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr2_+_20519776 0.276 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chrM_+_9452 0.275 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr11_+_98741871 0.270 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr7_-_100658364 0.268 ENSMUST00000107043.1
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_+_130577334 0.265 ENSMUST00000059145.7
ENSMUST00000084513.4
Tacc2

transforming, acidic coiled-coil containing protein 2

chr19_+_6057888 0.264 ENSMUST00000043074.5
ENSMUST00000178310.1
Fau

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

chr17_+_47630690 0.258 ENSMUST00000024779.8
Usp49
ubiquitin specific peptidase 49
chr15_-_98831498 0.250 ENSMUST00000168846.1
Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr12_+_55598917 0.245 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chrM_+_8600 0.241 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr16_-_84835484 0.239 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr4_-_117156144 0.238 ENSMUST00000102696.4
Rps8
ribosomal protein S8
chr10_+_116177351 0.236 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr9_+_27299205 0.236 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chrX_+_100729917 0.236 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr6_-_127769427 0.212 ENSMUST00000032500.8
Prmt8
protein arginine N-methyltransferase 8
chr9_+_108296853 0.209 ENSMUST00000035230.5
Amt
aminomethyltransferase
chr19_+_21272276 0.201 ENSMUST00000025659.4
Zfand5
zinc finger, AN1-type domain 5
chr11_-_103101609 0.198 ENSMUST00000103077.1
Plcd3
phospholipase C, delta 3
chr3_-_154328634 0.197 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr7_+_46796088 0.193 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1

general transcription factor II H, polypeptide 1

chrX_+_7919816 0.187 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_-_69681822 0.184 ENSMUST00000005336.2
Senp3
SUMO/sentrin specific peptidase 3
chr8_+_113643206 0.180 ENSMUST00000034219.4
ENSMUST00000095173.1
Syce1l

synaptonemal complex central element protein 1 like

chr15_+_80623499 0.176 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr3_-_10208569 0.175 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr10_-_35711891 0.168 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr2_-_30178422 0.161 ENSMUST00000100220.4
ENSMUST00000179795.1
D2Wsu81e

DNA segment, Chr 2, Wayne State University 81, expressed

chr11_-_94507337 0.150 ENSMUST00000040692.8
Mycbpap
MYCBP associated protein
chrX_+_20425688 0.146 ENSMUST00000115384.2
Phf16
PHD finger protein 16
chr18_-_36766198 0.143 ENSMUST00000061522.7
Dnd1
dead end homolog 1 (zebrafish)
chr6_-_21851914 0.141 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
Tspan12


tetraspanin 12


chr19_-_6057736 0.136 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr15_+_99670574 0.132 ENSMUST00000023758.7
Asic1
acid-sensing (proton-gated) ion channel 1
chr7_-_45830776 0.132 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr1_+_180726019 0.131 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr11_+_98741805 0.124 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr11_+_98753512 0.121 ENSMUST00000124072.1
Thra
thyroid hormone receptor alpha
chr3_+_51415986 0.112 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_+_95414078 0.111 ENSMUST00000107724.2
ENSMUST00000150884.1
ENSMUST00000107722.1
ENSMUST00000127713.1
Spop



speckle-type POZ protein



chr19_-_19001099 0.083 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr15_+_74516196 0.083 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr1_+_66468364 0.079 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr10_+_99263224 0.071 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr10_+_86705811 0.045 ENSMUST00000061458.7
ENSMUST00000075632.6
BC030307

cDNA sequence BC030307

chr9_-_21073494 0.042 ENSMUST00000010348.5
Fdx1l
ferredoxin 1-like
chr18_+_34840575 0.041 ENSMUST00000043484.7
Reep2
receptor accessory protein 2
chr16_-_16527364 0.036 ENSMUST00000069284.7
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr9_-_49798729 0.035 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chrX_+_42150672 0.031 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr9_+_35421541 0.028 ENSMUST00000119129.2
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr19_+_37436707 0.025 ENSMUST00000128184.1
Hhex
hematopoietically expressed homeobox
chr2_+_25272475 0.019 ENSMUST00000028341.4
Anapc2
anaphase promoting complex subunit 2
chr10_-_86705485 0.017 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr4_+_11191354 0.013 ENSMUST00000170901.1
Ccne2
cyclin E2
chr1_+_171329015 0.005 ENSMUST00000111300.1
Dedd
death effector domain-containing
chr2_+_68861433 0.001 ENSMUST00000028426.2
Cers6
ceramide synthase 6
chr7_+_111028951 0.001 ENSMUST00000005749.5
Ctr9
Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 3.4 GO:2000852 regulation of corticosterone secretion(GO:2000852)
1.7 8.4 GO:0035262 gonad morphogenesis(GO:0035262)
1.5 6.0 GO:0051866 general adaptation syndrome(GO:0051866)
1.2 3.7 GO:0032474 otolith morphogenesis(GO:0032474)
1.0 4.9 GO:0007386 compartment pattern specification(GO:0007386)
0.8 11.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.7 1.4 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.6 1.8 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.6 2.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 5.0 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.4 4.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.4 3.4 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.4 4.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 1.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 1.1 GO:0090526 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.6 GO:0030091 protein repair(GO:0030091)
0.3 0.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 1.2 GO:0007412 axon target recognition(GO:0007412)
0.3 2.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.3 0.8 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.3 1.3 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.2 0.7 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.2 4.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.2 0.5 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 4.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.9 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 3.2 GO:0007340 acrosome reaction(GO:0007340)
0.1 17.0 GO:0050807 regulation of synapse organization(GO:0050807)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.4 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 1.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.6 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.3 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 1.1 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.1 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.8 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.1 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.3 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.2 GO:0007128 meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.0 0.5 GO:0086036 mitochondrial calcium ion transport(GO:0006851) regulation of cardiac muscle cell membrane potential(GO:0086036)
0.0 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 3.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.0 GO:0008347 glial cell migration(GO:0008347)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.8 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.8 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.0 GO:0050913 sensory perception of bitter taste(GO:0050913)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 11.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 7.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 13.0 GO:0005581 collagen trimer(GO:0005581)
0.2 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 0.8 GO:1990357 terminal web(GO:1990357)
0.1 3.4 GO:0001741 XY body(GO:0001741)
0.1 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.1 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 1.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.2 GO:0070469 respiratory chain(GO:0070469)
0.1 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.9 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.1 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.3 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.5 1.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.5 1.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.4 3.4 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.4 1.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 2.2 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 4.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 0.9 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 1.3 GO:0038132 neuregulin binding(GO:0038132)
0.3 11.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 3.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.6 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.2 0.8 GO:0050436 microfibril binding(GO:0050436)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 0.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 4.9 GO:0005112 Notch binding(GO:0005112)
0.2 0.6 GO:0042806 fucose binding(GO:0042806)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 1.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.4 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.9 GO:0036122 BMP binding(GO:0036122)
0.1 2.3 GO:0035198 miRNA binding(GO:0035198)
0.1 0.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 2.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0070410 co-SMAD binding(GO:0070410)
0.1 5.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0019808 polyamine binding(GO:0019808)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0008748 N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 4.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.8 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)