Motif ID: Gata3

Z-value: 1.405


Transcription factors associated with Gata3:

Gene SymbolEntrez IDGene Name
Gata3 ENSMUSG00000015619.10 Gata3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata3mm10_v2_chr2_-_9890026_9890035-0.521.2e-02Click!


Activity profile for motif Gata3.

activity profile for motif Gata3


Sorted Z-values histogram for motif Gata3

Sorted Z-values for motif Gata3



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 7.981 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_+_13751297 6.240 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_+_67234620 5.166 ENSMUST00000176029.1
Ebf2
early B cell factor 2
chr7_-_103853199 4.223 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr2_+_121289589 4.100 ENSMUST00000094639.3
Map1a
microtubule-associated protein 1 A
chr11_+_32276400 4.095 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr1_+_6730051 4.037 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr9_+_65265173 3.877 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chrX_+_143518671 3.856 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr2_-_172043466 3.768 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr1_+_6730135 3.329 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chrX_+_143518576 3.316 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_+_32276893 3.310 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr8_-_8639363 3.186 ENSMUST00000152698.1
Efnb2
ephrin B2
chr3_+_102010138 3.149 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr19_-_24861828 2.765 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr19_+_41482632 2.665 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr1_+_153665666 2.471 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr7_-_103843154 2.452 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr7_-_75308373 2.376 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 349 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 13.7 GO:0015671 oxygen transport(GO:0015671)
1.5 9.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 8.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
1.0 6.9 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.5 6.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 5.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 5.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.4 5.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.3 4.2 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.4 4.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.6 3.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 3.7 GO:0060013 righting reflex(GO:0060013)
0.9 3.6 GO:0060032 notochord regression(GO:0060032)
0.5 3.6 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.4 3.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.7 3.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 3.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 3.3 GO:0006334 nucleosome assembly(GO:0006334)
0.8 3.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.5 3.1 GO:0032796 uropod organization(GO:0032796)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 169 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 9.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 9.1 GO:0005875 microtubule associated complex(GO:0005875)
0.1 8.2 GO:0016363 nuclear matrix(GO:0016363)
0.2 6.5 GO:0035371 microtubule plus-end(GO:0035371)
0.2 6.3 GO:0043034 costamere(GO:0043034)
0.1 4.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 4.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 4.3 GO:0000792 heterochromatin(GO:0000792)
0.1 4.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 4.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 4.0 GO:0043195 terminal bouton(GO:0043195)
0.3 3.8 GO:0097542 ciliary tip(GO:0097542)
0.1 3.6 GO:0008180 COP9 signalosome(GO:0008180)
0.1 2.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.9 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 2.7 GO:0070545 PeBoW complex(GO:0070545)
0.2 2.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 2.2 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 244 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 15.1 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
2.7 13.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 7.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.4 6.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 6.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 4.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 3.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.1 3.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 3.6 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 3.5 GO:0019904 protein domain specific binding(GO:0019904)
0.1 3.4 GO:0005518 collagen binding(GO:0005518)
0.2 3.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.9 2.7 GO:0043532 angiostatin binding(GO:0043532)
0.5 2.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 2.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 2.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)