Motif ID: Sin3a

Z-value: 1.137


Transcription factors associated with Sin3a:

Gene SymbolEntrez IDGene Name
Sin3a ENSMUSG00000042557.8 Sin3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sin3amm10_v2_chr9_+_57076395_570764110.593.3e-03Click!


Activity profile for motif Sin3a.

activity profile for motif Sin3a


Sorted Z-values histogram for motif Sin3a

Sorted Z-values for motif Sin3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Sin3a

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_64340225 4.269 ENSMUST00000175965.2
ENSMUST00000115145.3
 Onecut2

one cut domain, family member 2

chr6_-_39206782 2.510 ENSMUST00000002305.8
 Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr12_-_64965496 2.034 ENSMUST00000021331.7
 Klhl28
kelch-like 28
chr19_+_59458372 1.881 ENSMUST00000062216.3
 Emx2
empty spiracles homeobox 2
chr6_+_85587524 1.764 ENSMUST00000072018.5
 Alms1
Alstrom syndrome 1
chr5_+_88886809 1.697 ENSMUST00000148750.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chrX_+_58030999 1.673 ENSMUST00000088631.4
ENSMUST00000088629.3
 Zic3

zinc finger protein of the cerebellum 3

chr7_-_70360593 1.627 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chrX_-_147554050 1.605 ENSMUST00000112819.2
ENSMUST00000136789.1
 Lrch2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr6_-_38875923 1.590 ENSMUST00000162359.1
 Hipk2
homeodomain interacting protein kinase 2
chrX_+_103356464 1.583 ENSMUST00000116547.2
 Chic1
cysteine-rich hydrophobic domain 1
chrX_+_69360294 1.574 ENSMUST00000033532.6
 Aff2
AF4/FMR2 family, member 2
chr6_-_38875965 1.526 ENSMUST00000160360.1
 Hipk2
homeodomain interacting protein kinase 2
chr12_+_64965742 1.518 ENSMUST00000066296.7
 Fam179b
family with sequence similarity 179, member B
chr1_-_10232670 1.505 ENSMUST00000088615.4
ENSMUST00000131556.1
 Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

chr14_-_56811464 1.491 ENSMUST00000173954.1
 Zmym5
zinc finger, MYM-type 5
chr2_-_60963192 1.486 ENSMUST00000028347.6
 Rbms1
RNA binding motif, single stranded interacting protein 1
chr18_-_72351009 1.482 ENSMUST00000073379.5
 Dcc
deleted in colorectal carcinoma
chr14_-_98169542 1.441 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr6_+_34745952 1.420 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
 Cald1


caldesmon 1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 456 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.5 4.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 3.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.7 3.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.4 2.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 2.9 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442)
0.4 2.5 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.3 2.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 2.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.2 2.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 2.1 GO:0015701 bicarbonate transport(GO:0015701)
0.2 2.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 2.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 1.9 GO:0046548 retinal rod cell development(GO:0046548)
0.2 1.9 GO:0016322 neuron remodeling(GO:0016322)
0.4 1.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.3 1.7 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.3 1.7 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.4 1.6 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.3 1.6 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 157 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.3 GO:0005814 centriole(GO:0005814)
0.2 3.7 GO:0097470 ribbon synapse(GO:0097470)
0.0 3.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.5 GO:0016605 PML body(GO:0016605)
0.1 3.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 3.1 GO:0005844 polysome(GO:0005844)
0.0 3.1 GO:0000922 spindle pole(GO:0000922)
0.3 3.0 GO:0030478 actin cap(GO:0030478)
0.2 2.7 GO:0032584 growth cone membrane(GO:0032584)
0.0 2.5 GO:0005681 spliceosomal complex(GO:0005681)
0.1 2.1 GO:0010369 chromocenter(GO:0010369)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.3 1.9 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.9 GO:0016342 catenin complex(GO:0016342)
0.2 1.8 GO:0016589 NURF complex(GO:0016589)
0.1 1.8 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.8 GO:0090544 BAF-type complex(GO:0090544)
0.3 1.7 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.4 1.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 254 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 18.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 6.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 4.8 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.5 4.2 GO:0046790 virion binding(GO:0046790)
0.0 3.9 GO:0008017 microtubule binding(GO:0008017)
0.6 3.4 GO:0005042 netrin receptor activity(GO:0005042)
0.4 3.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 3.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.5 2.7 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.1 2.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 2.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 2.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.6 1.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 1.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.6 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)