Motif ID: Rora

Z-value: 0.461


Transcription factors associated with Rora:

Gene SymbolEntrez IDGene Name
Rora ENSMUSG00000032238.11 Rora

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Roramm10_v2_chr9_+_68653761_68653786-0.145.3e-01Click!


Activity profile for motif Rora.

activity profile for motif Rora


Sorted Z-values histogram for motif Rora

Sorted Z-values for motif Rora



Network of associatons between targets according to the STRING database.



First level regulatory network of Rora

PNG image of the network

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Top targets:


Showing 1 to 20 of 188 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_86191764 0.833 ENSMUST00000026036.4
Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr9_-_75597643 0.760 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr1_+_127204986 0.670 ENSMUST00000038361.4
Mgat5
mannoside acetylglucosaminyltransferase 5
chr17_-_17624458 0.654 ENSMUST00000041047.2
Lnpep
leucyl/cystinyl aminopeptidase
chr1_+_6734827 0.642 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr3_-_107517321 0.630 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr15_-_72546279 0.610 ENSMUST00000044624.6
Kcnk9
potassium channel, subfamily K, member 9
chr1_+_159737510 0.606 ENSMUST00000111669.3
Tnr
tenascin R
chr7_-_12422751 0.581 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr17_+_88626549 0.580 ENSMUST00000163588.1
ENSMUST00000064035.6
Ston1

stonin 1

chr12_+_33314277 0.573 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr16_+_11406618 0.552 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr2_-_5676046 0.529 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr2_-_130839683 0.527 ENSMUST00000119422.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr1_-_191907527 0.526 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr2_+_4300462 0.498 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr3_-_158562199 0.483 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr14_+_20929416 0.482 ENSMUST00000022369.7
Vcl
vinculin
chr6_+_29853746 0.429 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr5_+_19227046 0.428 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.2 0.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.2 0.6 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.6 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:2000809 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.4 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.3 GO:1901524 regulation of autophagosome maturation(GO:1901096) regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.3 GO:0043313 regulation of neutrophil degranulation(GO:0043313)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.6 GO:0072534 perineuronal net(GO:0072534)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224) cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 0.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)